(11 nodes) Regulation of amyloid precursor protein biosynthetic process network (Enhydra lutris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111144801	LOW QUALITY PROTEIN: integral membrane protein 2C. (267 aa)
	LOC111146913	Integral membrane protein 2B. (266 aa)
	LOC111146817	N-terminal EF-hand calcium-binding protein 1. (351 aa)
	LOC111151702	Protein AATF isoform X1. (565 aa)
	LOC111138884	Nicastrin isoform X1. (709 aa)
	LOC111150910	O-acyltransferase. (552 aa)
	LOC111142254	PRKC apoptosis WT1 regulator protein. (340 aa)
	LOC111155713	Beta-secretase 2 isoform X1; Belongs to the peptidase A1 family. (511 aa)
	LOC111161701	ATP-binding cassette sub-family A member 7 isoform X1. (2160 aa)
	LOC111160933	Integral membrane protein 2A isoform X1. (263 aa)
	LOC111141501	N-terminal EF-hand calcium-binding protein 3. (360 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111138884	LOC111155713	A0A2Y9IH76	A0A2Y9KD89	Nicastrin isoform X1.	Beta-secretase 2 isoform X1; Belongs to the peptidase A1 family.	0.498
LOC111141501	LOC111155713	A0A2Y9IR64	A0A2Y9KD89	N-terminal EF-hand calcium-binding protein 3.	Beta-secretase 2 isoform X1; Belongs to the peptidase A1 family.	0.474
LOC111146817	LOC111155713	A0A2Y9JCA9	A0A2Y9KD89	N-terminal EF-hand calcium-binding protein 1.	Beta-secretase 2 isoform X1; Belongs to the peptidase A1 family.	0.474
LOC111155713	LOC111138884	A0A2Y9KD89	A0A2Y9IH76	Beta-secretase 2 isoform X1; Belongs to the peptidase A1 family.	Nicastrin isoform X1.	0.498
LOC111155713	LOC111141501	A0A2Y9KD89	A0A2Y9IR64	Beta-secretase 2 isoform X1; Belongs to the peptidase A1 family.	N-terminal EF-hand calcium-binding protein 3.	0.474
LOC111155713	LOC111146817	A0A2Y9KD89	A0A2Y9JCA9	Beta-secretase 2 isoform X1; Belongs to the peptidase A1 family.	N-terminal EF-hand calcium-binding protein 1.	0.474