node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC111139105 | LOC111143075 | A0A2Y9IE48 | A0A2Y9IY12 | Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Delta(24)-sterol reductase. | 0.425 |
LOC111139105 | LOC111154190 | A0A2Y9IE48 | A0A2Y9KCS3 | Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). | 0.958 |
LOC111141115 | LOC111148924 | A0A2Y9IT68 | A0A2Y9JLH6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | 0.868 |
LOC111141115 | LOC111156454 | A0A2Y9IT68 | A0A2Y9KGY6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.491 |
LOC111142538 | LOC111158708 | A0A2Y9IVX4 | A0A2Y9KSC8 | GREB1-like protein. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.475 |
LOC111143075 | LOC111139105 | A0A2Y9IY12 | A0A2Y9IE48 | Delta(24)-sterol reductase. | Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.425 |
LOC111147588 | LOC111149160 | A0A2Y9JNN5 | A0A2Y9JL49 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. | Tumor protein 63-like. | 0.900 |
LOC111148924 | LOC111141115 | A0A2Y9JLH6 | A0A2Y9IT68 | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.868 |
LOC111148924 | LOC111156454 | A0A2Y9JLH6 | A0A2Y9KGY6 | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.973 |
LOC111148924 | LOC111156661 | A0A2Y9JLH6 | A0A2Y9KJX6 | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | Bone morphogenetic protein 6. | 0.541 |
LOC111149160 | LOC111147588 | A0A2Y9JL49 | A0A2Y9JNN5 | Tumor protein 63-like. | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. | 0.900 |
LOC111151784 | LOC111158202 | A0A2Y9K867 | A0A2Y9KWZ8 | LIM/homeobox protein Lhx1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.607 |
LOC111152355 | LOC111154103 | A0A2Y9JZU0 | A0A2Y9K6B0 | Bcl-2 homologous antagonist/killer. | Protein GREB1 isoform X1. | 0.443 |
LOC111153296 | LOC111155368 | A0A2Y9KES6 | A0A2Y9KCK8 | Stimulated by retinoic acid gene 6 protein homolog isoform X2. | chromodomain-helicase-DNA-binding protein 7. | 0.562 |
LOC111154103 | LOC111152355 | A0A2Y9K6B0 | A0A2Y9JZU0 | Protein GREB1 isoform X1. | Bcl-2 homologous antagonist/killer. | 0.443 |
LOC111154103 | LOC111158708 | A0A2Y9K6B0 | A0A2Y9KSC8 | Protein GREB1 isoform X1. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.800 |
LOC111154190 | LOC111139105 | A0A2Y9KCS3 | A0A2Y9IE48 | 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). | Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.958 |
LOC111155368 | LOC111153296 | A0A2Y9KCK8 | A0A2Y9KES6 | chromodomain-helicase-DNA-binding protein 7. | Stimulated by retinoic acid gene 6 protein homolog isoform X2. | 0.562 |
LOC111156454 | LOC111141115 | A0A2Y9KGY6 | A0A2Y9IT68 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.491 |
LOC111156454 | LOC111148924 | A0A2Y9KGY6 | A0A2Y9JLH6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | 0.973 |