STRINGSTRING
LOC111145162 LOC111145162 LOC111162355 LOC111162355 LOC111162047 LOC111162047 LOC111161896 LOC111161896 LOC111160883 LOC111160883 LOC111160164 LOC111160164 LOC111161420 LOC111161420 LOC111159845 LOC111159845 LOC111162134 LOC111162134 LOC111159987 LOC111159987 LOC111158426 LOC111158426 LOC111160810 LOC111160810 LOC111161298 LOC111161298 LOC111158091 LOC111158091 LOC111160641 LOC111160641 LOC111159982 LOC111159982 LOC111159933 LOC111159933 LOC111158579 LOC111158579 LOC111160115 LOC111160115 LOC111157130 LOC111157130 LOC111157077 LOC111157077 LOC111160084 LOC111160084 LOC111159816 LOC111159816 LOC111158128 LOC111158128 LOC111156657 LOC111156657 LOC111159847 LOC111159847 LOC111157800 LOC111157800 LOC111156379 LOC111156379 LOC111158708 LOC111158708 LOC111157985 LOC111157985 LOC111155546 LOC111155546 LOC111156802 LOC111156802 LOC111156955 LOC111156955 LOC111156710 LOC111156710 LOC111155271 LOC111155271 LOC111153339 LOC111153339 LOC111156005 LOC111156005 LOC111155447 LOC111155447 LOC111155193 LOC111155193 LOC111152830 LOC111152830 LOC111155000 LOC111155000 LOC111152376 LOC111152376 LOC111155042 LOC111155042 LOC111153700 LOC111153700 LOC111153691 LOC111153691 LOC111154976 LOC111154976 LOC111154665 LOC111154665 LOC111152110 LOC111152110 LOC111152038 LOC111152038 LOC111154393 LOC111154393 LOC111152017 LOC111152017 LOC111153272 LOC111153272 LOC111151807 LOC111151807 LOC111154157 LOC111154157 LOC111152943 LOC111152943 LOC111152768 LOC111152768 LOC111153852 LOC111153852 LOC111153716 LOC111153716 LOC111151082 LOC111151082 LOC111152248 LOC111152248 LOC111151618 LOC111151618 LOC111150173 LOC111150173 LOC111150020 LOC111150020 LOC111152355 LOC111152355 LOC111152340 LOC111152340 LOC111151954 LOC111151954 LOC111152016 LOC111152016 LOC111151964 LOC111151964 LOC111152010 LOC111152010 LOC111151779 LOC111151779 LOC111151976 LOC111151976 LOC111149369 LOC111149369 LOC111151715 LOC111151715 LOC111151595 LOC111151595 LOC111151576 LOC111151576 LOC111151572 LOC111151572 LOC111149192 LOC111149192 LOC111149975 LOC111149975 LOC111150797 LOC111150797 LOC111150193 LOC111150193 LOC111148116 LOC111148116 LOC111150207 LOC111150207 LOC111147588 LOC111147588 LOC111147522 LOC111147522 LOC111147356 LOC111147356 LOC111149348 LOC111149348 LOC111148445 LOC111148445 LOC111149339 LOC111149339 LOC111149160 LOC111149160 LOC111148886 LOC111148886 LOC111148174 LOC111148174 LOC111148068 LOC111148068 LOC111147123 LOC111147123 LOC111145671 LOC111145671 LOC111147562 LOC111147562 LOC111147365 LOC111147365 LOC111146345 LOC111146345 LOC111145184 LOC111145184 LOC111146911 LOC111146911 LOC111146253 LOC111146253 LOC111147074 LOC111147074 LOC111146777 LOC111146777 LOC111146471 LOC111146471 LOC111146071 LOC111146071 LOC111144939 LOC111144939 LOC111144500 LOC111144500 LOC111145189 LOC111145189 LOC111144836 LOC111144836 LOC111145116 LOC111145116 LOC111144630 LOC111144630 LOC111143629 LOC111143629 LOC111144293 LOC111144293 LOC111143728 LOC111143728 LOC111143707 LOC111143707 LOC111142759 LOC111142759 LOC111141640 LOC111141640 LOC111142179 LOC111142179 LOC111142867 LOC111142867 LOC111141115 LOC111141115 LOC111141108 LOC111141108 LOC111142258 LOC111142258 LOC111141287 LOC111141287 LOC111142115 LOC111142115 LOC111141730 LOC111141730 LOC111141470 LOC111141470 LOC111141657 LOC111141657 LOC111140569 LOC111140569 LOC111140346 LOC111140346 LOC111138995 LOC111138995 LOC111140886 LOC111140886 LOC111140204 LOC111140204 LOC111138884 LOC111138884 LOC111139249 LOC111139249 LOC111139086 LOC111139086
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111145162F-box/WD repeat-containing protein 1A isoform X1. (605 aa)
LOC111162355Interferon regulatory factor 6. (462 aa)
LOC111162047Bone morphogenetic protein 4 isoform X1. (456 aa)
LOC111161896Serine/threonine-protein kinase STK11 isoform X1. (513 aa)
LOC111160883LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (387 aa)
LOC111160164arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X1. (1191 aa)
LOC111161420Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
LOC111159845Intraflagellar transport protein 74 homolog. (600 aa)
LOC111162134Glypican-3 isoform X1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
LOC111159987alpha-N-acetylneuraminide alpha-2,8-sialyltransferase isoform X1; Belongs to the glycosyltransferase 29 family. (356 aa)
LOC111158426Metastasis-associated protein MTA3 isoform X1. (591 aa)
LOC111160810Bcl-2-like protein 2. (193 aa)
LOC111161298Protein salvador homolog 1. (384 aa)
LOC111158091Serine/threonine-protein kinase/endoribonuclease IRE1. (975 aa)
LOC111160641Kallikrein-8-like; Belongs to the peptidase S1 family. (259 aa)
LOC111159982Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
LOC111159933Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC111158579Pancreas/duodenum homeobox protein 1. (281 aa)
LOC111160115Signal transducer and activator of transcription. (844 aa)
LOC111157130cAMP-dependent protein kinase catalytic subunit PRKX; Belongs to the protein kinase superfamily. (361 aa)
LOC111157077Insulin-like growth factor-binding protein 3 isoform X2. (299 aa)
LOC111160084LOW QUALITY PROTEIN: X-box-binding protein 1. (392 aa)
LOC111159816Prohibitin. (299 aa)
LOC111158128Transcription factor SOX-9 isoform X1. (510 aa)
LOC111156657Homeobox protein Nkx-3.1. (229 aa)
LOC111159847Angiopoietin-1 receptor. (1124 aa)
LOC111157800Keratin, type II cytoskeletal 2 epidermal; Belongs to the intermediate filament family. (659 aa)
LOC111156379Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (509 aa)
LOC111158708Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (599 aa)
LOC111157985Homeobox protein Nkx-2.8. (238 aa)
LOC111155546Zinc finger E-box-binding homeobox 1 isoform X1. (1125 aa)
LOC111156802Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
LOC111156955Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
LOC111156710Leukocyte elastase inhibitor; Belongs to the serpin family. (396 aa)
LOC111155271Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa)
LOC111153339LOW QUALITY PROTEIN: NADPH oxidase 5. (720 aa)
LOC111156005Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (341 aa)
LOC111155447Epidermal retinol dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa)
LOC111155193alpha-1,4-N-acetylglucosaminyltransferase isoform X1. (391 aa)
LOC111152830Heat shock factor protein 4 isoform X1. (492 aa)
LOC111155000ELL-associated factor 2. (264 aa)
LOC111152376Peroxisome proliferator-activated receptor delta. (441 aa)
LOC111155042Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (927 aa)
LOC111153700Apolipoprotein A-I isoform X1. (266 aa)
LOC111153691SID1 transmembrane family member 2 isoform X1. (853 aa)
LOC111154976Lysyl oxidase homolog 2 isoform X1. (779 aa)
LOC111154665LOW QUALITY PROTEIN: ephrin type-A receptor 2. (975 aa)
LOC111152110Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
LOC111152038Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
LOC111154393Disks large homolog 2 isoform X1. (919 aa)
LOC111152017Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
LOC111153272Homeobox protein Nkx-2.6. (302 aa)
LOC111151807Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
LOC111154157Integrin beta-1-binding protein 1. (199 aa)
LOC111152943Epithelial splicing regulatory protein 2. (717 aa)
LOC111152768Cadherin-13. (713 aa)
LOC111153852D(2) dopamine receptor isoform X2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
LOC111153716LOW QUALITY PROTEIN: transcriptional coactivator YAP1. (422 aa)
LOC111151082H2.0-like homeobox protein. (483 aa)
LOC111152248Tumor necrosis factor isoform X1; Belongs to the tumor necrosis factor family. (234 aa)
LOC111151618Insulin-like growth factor-binding protein 4. (258 aa)
LOC111150173Leucine-rich repeat-containing G-protein coupled receptor 4 isoform X2. (951 aa)
LOC111150020ETS homologous factor isoform X1. (300 aa)
LOC111152355Bcl-2 homologous antagonist/killer. (211 aa)
LOC111152340CD109 antigen. (1445 aa)
LOC111151954Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
LOC111152016Transcription intermediary factor 1-alpha isoform X1. (1050 aa)
LOC111151964Intraflagellar transport protein 57 homolog. (429 aa)
LOC111152010Resistin-like beta. (109 aa)
LOC111151779Pigment epithelium-derived factor; Belongs to the serpin family. (231 aa)
LOC111151976Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
LOC111149369Proepiregulin. (110 aa)
LOC111151715Pigment epithelium-derived factor-like; Belongs to the serpin family. (417 aa)
LOC111151595Neurofibromin isoform X1. (2841 aa)
LOC111151576T-box transcription factor TBX2. (713 aa)
LOC111151572Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
LOC111149192Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
LOC111149975Bcl2-associated agonist of cell death. (168 aa)
LOC111150797Prospero homeobox protein 1 isoform X1. (738 aa)
LOC111150193Cyclin-dependent kinase inhibitor 1C. (263 aa)
LOC111148116Protransforming growth factor alpha. (159 aa)
LOC111150207Putative transcription factor Ovo-like 1. (267 aa)
LOC111147588Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
LOC111147522Bombesin receptor-activated protein C6orf89 homolog isoform X1. (355 aa)
LOC111147356BMP-binding endothelial regulator protein. (685 aa)
LOC111149348Amphiregulin. (283 aa)
LOC111148445Myocyte-specific enhancer factor 2C isoform X1. (483 aa)
LOC111149339Paired mesoderm homeobox protein 2B. (228 aa)
LOC111149160Tumor protein 63-like. (333 aa)
LOC111148886Collagen alpha-1(VIII) chain isoform X2. (755 aa)
LOC111148174Intraflagellar transport protein 80 homolog isoform X1. (777 aa)
LOC111148068Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (693 aa)
LOC111147123Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (320 aa)
LOC111145671Neurogenic locus notch homolog protein 1. (2562 aa)
LOC111147562Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (514 aa)
LOC111147365Interleukin-6 isoform X2. (212 aa)
LOC111146345Notch-regulated ankyrin repeat-containing protein. (114 aa)
LOC111145184Homeobox protein HMX2. (272 aa)
LOC111146911Retinoblastoma-associated protein. (938 aa)
LOC111146253Beta-1,4-galactosyltransferase 1. (400 aa)
LOC111147074Dachshund homolog 1. (704 aa)
LOC111146777Metastasis suppressor protein 1 isoform X1. (759 aa)
LOC111146471Serine/threonine-protein kinase 3 isoform X1. (491 aa)
LOC111146071Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
LOC111144939Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (406 aa)
LOC111144500THAP domain-containing protein 1 isoform X1. (213 aa)
LOC111145189V-set and transmembrane domain-containing protein 4. (319 aa)
LOC111144836Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
LOC111145116Proliferation marker protein Ki-67 isoform X1. (2394 aa)
LOC111144630Fibrinogen-like protein 1 isoform X1. (334 aa)
LOC111143629Collagen alpha-2(VIII) chain. (699 aa)
LOC111144293Prokineticin-2 isoform X1. (129 aa)
LOC111143728Prokineticin-1. (105 aa)
LOC111143707Methylosome protein 50 isoform X1. (342 aa)
LOC111142759Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
LOC111141640Intraflagellar transport protein 52 homolog. (446 aa)
LOC111142179Leucine-rich repeat-containing G-protein coupled receptor 5 isoform X1. (907 aa)
LOC111142867Neurogenic locus notch homolog protein 2. (2471 aa)
LOC111141115Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
LOC111141108Transcriptional activator protein Pur-alpha. (322 aa)
LOC111142258C-type lectin domain family 12 member B. (276 aa)
LOC111141287Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
LOC111142115Cyclin-dependent kinase inhibitor 1B. (198 aa)
LOC111141730Fermitin family homolog 1. (677 aa)
LOC111141470Serine/threonine-protein kinase 4. (487 aa)
LOC111141657CCAAT/enhancer-binding protein. (346 aa)
LOC111140569Prohibitin. (175 aa)
LOC111140346Keratinocyte differentiation factor 1. (397 aa)
LOC111138995Ras GTPase-activating-like protein IQGAP3. (1629 aa)
LOC111140886Follistatin isoform X1. (344 aa)
LOC11114020414-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
LOC111138884Nicastrin isoform X1. (709 aa)
LOC111139249Folliculin. (579 aa)
LOC111139086LOW QUALITY PROTEIN: protein patched homolog 1. (1451 aa)
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
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