STRINGSTRING
LOC111143728 LOC111143728 LOC111162047 LOC111162047 LOC111162035 LOC111162035 LOC111161731 LOC111161731 LOC111160717 LOC111160717 LOC111160164 LOC111160164 LOC111161831 LOC111161831 LOC111161816 LOC111161816 LOC111158898 LOC111158898 LOC111161440 LOC111161440 LOC111160297 LOC111160297 LOC111159987 LOC111159987 LOC111161374 LOC111161374 LOC111161519 LOC111161519 LOC111158426 LOC111158426 LOC111160742 LOC111160742 LOC111159568 LOC111159568 LOC111160614 LOC111160614 LOC111160605 LOC111160605 LOC111157941 LOC111157941 LOC111157602 LOC111157602 LOC111157534 LOC111157534 LOC111159982 LOC111159982 LOC111159933 LOC111159933 LOC111158579 LOC111158579 LOC111160084 LOC111160084 LOC111158128 LOC111158128 LOC111158087 LOC111158087 LOC111159164 LOC111159164 LOC111157856 LOC111157856 LOC111156293 LOC111156293 LOC111158641 LOC111158641 LOC111158743 LOC111158743 LOC111155872 LOC111155872 LOC111155506 LOC111155506 LOC111158107 LOC111158107 LOC111158074 LOC111158074 LOC111157341 LOC111157341 LOC111157042 LOC111157042 LOC111156661 LOC111156661 LOC111156656 LOC111156656 LOC111156802 LOC111156802 LOC111156955 LOC111156955 LOC111153902 LOC111153902 LOC111154641 LOC111154641 LOC111156005 LOC111156005 LOC111153061 LOC111153061 LOC111152830 LOC111152830 LOC111152038 LOC111152038 LOC111152017 LOC111152017 LOC111153272 LOC111153272 LOC111151807 LOC111151807 LOC111154152 LOC111154152 LOC111152943 LOC111152943 LOC111152768 LOC111152768 LOC111151241 LOC111151241 LOC111153716 LOC111153716 LOC111153395 LOC111153395 LOC111151082 LOC111151082 LOC111152248 LOC111152248 LOC111152683 LOC111152683 LOC111152343 LOC111152343 LOC111152224 LOC111152224 LOC111152070 LOC111152070 LOC111151976 LOC111151976 LOC111151595 LOC111151595 LOC111151572 LOC111151572 LOC111149192 LOC111149192 LOC111151294 LOC111151294 LOC111151211 LOC111151211 LOC111151100 LOC111151100 LOC111149975 LOC111149975 LOC111150998 LOC111150998 LOC111150885 LOC111150885 LOC111148570 LOC111148570 LOC111150797 LOC111150797 LOC111150697 LOC111150697 LOC111150671 LOC111150671 LOC111148277 LOC111148277 LOC111148255 LOC111148255 LOC111149333 LOC111149333 LOC111148116 LOC111148116 LOC111148765 LOC111148765 LOC111149743 LOC111149743 LOC111147588 LOC111147588 LOC111149705 LOC111149705 LOC111149262 LOC111149262 LOC111149273 LOC111149273 LOC111149160 LOC111149160 LOC111146679 LOC111146679 LOC111147788 LOC111147788 LOC111148193 LOC111148193 LOC111147441 LOC111147441 LOC111147726 LOC111147726 LOC111145671 LOC111145671 LOC111147421 LOC111147421 LOC111145534 LOC111145534 LOC111147562 LOC111147562 LOC111146397 LOC111146397 LOC111146345 LOC111146345 LOC111145184 LOC111145184 LOC111146253 LOC111146253 LOC111146783 LOC111146783 LOC111144557 LOC111144557 LOC111144527 LOC111144527 LOC111146071 LOC111146071 LOC111145217 LOC111145217 LOC111145491 LOC111145491 LOC111144681 LOC111144681 LOC111145159 LOC111145159 LOC111144836 LOC111144836 LOC111145001 LOC111145001 LOC111144679 LOC111144679 LOC111144482 LOC111144482 LOC111144443 LOC111144443 LOC111144101 LOC111144101 LOC111143268 LOC111143268 LOC111143238 LOC111143238 LOC111143984 LOC111143984 LOC111143174 LOC111143174 LOC111142867 LOC111142867 LOC111141115 LOC111141115 LOC111141639 LOC111141639 LOC111141425 LOC111141425 LOC111141287 LOC111141287 LOC111141664 LOC111141664 LOC111138995 LOC111138995 LOC111140494 LOC111140494 LOC111140316 LOC111140316 LOC111139714 LOC111139714 LOC111139625 LOC111139625
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111143728Prokineticin-1. (105 aa)
LOC111162047Bone morphogenetic protein 4 isoform X1. (456 aa)
LOC111162035LOW QUALITY PROTEIN: extracellular matrix protein 1. (544 aa)
LOC111161731Myeloid-derived growth factor. (173 aa)
LOC111160717C5a anaphylatoxin chemotactic receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (349 aa)
LOC111160164arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X1. (1191 aa)
LOC111161831NAD-dependent protein deacetylase sirtuin-6 isoform X1. (359 aa)
LOC111161816Leucine-rich alpha-2-glycoprotein. (384 aa)
LOC111158898Vascular endothelial growth factor receptor 3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
LOC111161440Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa)
LOC111160297Integrin alpha-4 isoform X1; Belongs to the integrin alpha chain family. (1033 aa)
LOC111159987alpha-N-acetylneuraminide alpha-2,8-sialyltransferase isoform X1; Belongs to the glycosyltransferase 29 family. (356 aa)
LOC111161374Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC111161519Serine protease hepsin; Belongs to the peptidase S1 family. (417 aa)
LOC111158426Metastasis-associated protein MTA3 isoform X1. (591 aa)
LOC111160742C5a anaphylatoxin chemotactic receptor 2. (337 aa)
LOC111159568Protein-glutamine gamma-glutamyltransferase K isoform X1. (844 aa)
LOC111160614ER membrane protein complex subunit 10 isoform X1. (262 aa)
LOC111160605Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
LOC111157941Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (632 aa)
LOC111157602Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
LOC111157534Platelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (243 aa)
LOC111159982Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
LOC111159933Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC111158579Pancreas/duodenum homeobox protein 1. (281 aa)
LOC111160084LOW QUALITY PROTEIN: X-box-binding protein 1. (392 aa)
LOC111158128Transcription factor SOX-9 isoform X1. (510 aa)
LOC111158087Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
LOC111159164WD repeat-containing protein 48 isoform X1. (677 aa)
LOC111157856Transcription factor Sp1 isoform X1. (786 aa)
LOC1111562933-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
LOC111158641Junctional protein associated with coronary artery disease. (1369 aa)
LOC111158743VIP peptides. (170 aa)
LOC111155872Phosducin-like protein 3. (240 aa)
LOC111155506Early growth response protein 3 isoform X1. (462 aa)
LOC111158107Integrin beta; Belongs to the integrin beta chain family. (784 aa)
LOC111158074LOW QUALITY PROTEIN: granulins. (621 aa)
LOC111157341Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1013 aa)
LOC111157042Receptor protein-tyrosine kinase. (1154 aa)
LOC111156661Bone morphogenetic protein 6. (509 aa)
LOC111156656Ras-responsive element-binding protein 1 isoform X1. (1768 aa)
LOC111156802Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
LOC111156955Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
LOC111153902High mobility group protein B1. (215 aa)
LOC111154641Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
LOC111156005Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (341 aa)
LOC111153061Cadherin-3; Cadherins are calcium-dependent cell adhesion proteins. (852 aa)
LOC111152830Heat shock factor protein 4 isoform X1. (492 aa)
LOC111152038Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
LOC111152017Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
LOC111153272Homeobox protein Nkx-2.6. (302 aa)
LOC111151807Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
LOC111154152Protein odd-skipped-related 1. (267 aa)
LOC111152943Epithelial splicing regulatory protein 2. (717 aa)
LOC111152768Cadherin-13. (713 aa)
LOC111151241Signal transducer and activator of transcription. (802 aa)
LOC111153716LOW QUALITY PROTEIN: transcriptional coactivator YAP1. (422 aa)
LOC111153395Programmed cell death protein 6 isoform X1. (189 aa)
LOC111151082H2.0-like homeobox protein. (483 aa)
LOC111152248Tumor necrosis factor isoform X1; Belongs to the tumor necrosis factor family. (234 aa)
LOC111152683Apelin receptor early endogenous ligand. (54 aa)
LOC111152343Bone morphogenetic protein 5 isoform X1. (454 aa)
LOC111152224Fibrocystin. (4075 aa)
LOC111152070Pleiotrophin. (168 aa)
LOC111151976Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
LOC111151595Neurofibromin isoform X1. (2841 aa)
LOC111151572Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
LOC111149192Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
LOC111151294Syntaxin-binding protein 4 isoform X1. (557 aa)
LOC111151211Signal transducer and activator of transcription. (794 aa)
LOC111151100Interleukin-10. (178 aa)
LOC111149975Bcl2-associated agonist of cell death. (168 aa)
LOC111150998Lysine-specific demethylase 5B isoform X1. (1544 aa)
LOC111150885Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC111148570Placenta growth factor isoform X1; Belongs to the PDGF/VEGF growth factor family. (170 aa)
LOC111150797Prospero homeobox protein 1 isoform X1. (738 aa)
LOC111150697Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
LOC111150671Vasohibin-2 isoform X1. (470 aa)
LOC111148277LOW QUALITY PROTEIN: thrombospondin-4. (964 aa)
LOC111148255Angiogenic factor with G patch and FHA domains 1. (716 aa)
LOC111149333LOW QUALITY PROTEIN: odontogenic ameloblast-associated protein. (288 aa)
LOC111148116Protransforming growth factor alpha. (159 aa)
LOC111148765Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC111149743Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (383 aa)
LOC111147588Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
LOC111149705Vascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (207 aa)
LOC111149262Fibroblast growth factor-binding protein 1. (253 aa)
LOC111149273Epigen isoform X1. (153 aa)
LOC111149160Tumor protein 63-like. (333 aa)
LOC111146679Protein odd-skipped-related 2 isoform X1. (312 aa)
LOC111147788Tumor necrosis factor alpha-induced protein 3. (790 aa)
LOC111148193Reticulon. (1191 aa)
LOC111147441Homeobox protein DLX-5. (289 aa)
LOC111147726Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (572 aa)
LOC111145671Neurogenic locus notch homolog protein 1. (2562 aa)
LOC111147421Homeobox protein DLX-6. (288 aa)
LOC111145534C-C motif chemokine. (92 aa)
LOC111147562Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (514 aa)
LOC111146397Epidermal growth factor-like protein 7 isoform X1. (351 aa)
LOC111146345Notch-regulated ankyrin repeat-containing protein. (114 aa)
LOC111145184Homeobox protein HMX2. (272 aa)
LOC111146253Beta-1,4-galactosyltransferase 1. (400 aa)
LOC111146783Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
LOC111144557Zinc finger protein 703. (591 aa)
LOC111144527Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (421 aa)
LOC111146071Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
LOC111145217Transcription factor 7-like 2 isoform X1. (625 aa)
LOC111145491C-C motif chemokine 24. (323 aa)
LOC111144681Growth/differentiation factor 2. (429 aa)
LOC111145159NAD-dependent protein deacetylase sirtuin-1 isoform X1. (751 aa)
LOC111144836Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
LOC111145001Secretogranin-2. (618 aa)
LOC111144679Nodal homolog. (348 aa)
LOC111144482Secreted frizzled-related protein 1-like. (250 aa)
LOC111144443Secreted frizzled-related protein 1. (314 aa)
LOC111144101Hepatocyte growth factor-like protein; Belongs to the peptidase S1 family. Plasminogen subfamily. (711 aa)
LOC111143268Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (292 aa)
LOC111143238GTPase NRas. (189 aa)
LOC1111439845-hydroxytryptamine receptor 2B. (504 aa)
LOC111143174Transcription factor AP-1; Belongs to the bZIP family. (334 aa)
LOC111142867Neurogenic locus notch homolog protein 2. (2471 aa)
LOC111141115Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
LOC111141639LOW QUALITY PROTEIN: bone morphogenetic protein 2. (395 aa)
LOC111141425Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
LOC111141287Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
LOC111141664Serine/arginine-rich splicing factor 6 isoform X1. (344 aa)
LOC111138995Ras GTPase-activating-like protein IQGAP3. (1629 aa)
LOC111140494High mobility group protein B1-like. (141 aa)
LOC111140316GTPase HRas isoform X1. (189 aa)
LOC111139714Zinc finger protein 304. (654 aa)
LOC111139625Zinc finger protein 580. (172 aa)
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
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