52 items (Enhydra lutris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111153936	G protein-activated inward rectifier potassium channel 4. (429 aa)
	LOC111162032	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
	LOC111161345	ATP-sensitive inward rectifier potassium channel 8. (424 aa)
	LOC111159786	Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (601 aa)
	LOC111161325	ATP-binding cassette sub-family C member 9 isoform X1. (1549 aa)
	LOC111161469	Sodium channel subunit beta-1 isoform X1. (218 aa)
	LOC111161331	Plakophilin-2. (868 aa)
	LOC111160952	Potassium voltage-gated channel subfamily E regulatory beta subunit 5. (137 aa)
	LOC111160808	relA-associated inhibitor. (829 aa)
	LOC111160434	Lysosomal alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family. (952 aa)
	LOC111158831	Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
	LOC111159579	Potassium voltage-gated channel subfamily E member 3. (99 aa)
	LOC111158151	Inward rectifier potassium channel 2. (427 aa)
	LOC111158041	Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (334 aa)
	LOC111159674	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2191 aa)
	LOC111159034	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
	LOC111158127	Myosin light chain 4. (191 aa)
	LOC111155505	Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (660 aa)
	LOC111156317	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform X1. (166 aa)
	LOC111153841	Sodium channel subunit beta-3. (215 aa)
	LOC111154883	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
	LOC111155823	Potassium voltage-gated channel subfamily E member 2. (123 aa)
	LOC111155807	Potassium voltage-gated channel subfamily E member 1. (130 aa)
	LOC111155265	Voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X2. (1110 aa)
	LOC111154435	Potassium voltage-gated channel subfamily H member 2 isoform X1. (1158 aa)
	LOC111153775	Sodium channel subunit beta-2. (215 aa)
	LOC111153772	Sodium channel subunit beta-4 isoform X1. (228 aa)
	LOC111151081	Troponin I, slow skeletal muscle. (187 aa)
	LOC111151698	Telethonin isoform X1. (177 aa)
	LOC111149479	Troponin I, fast skeletal muscle. (185 aa)
	LOC111149772	Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (667 aa)
	LOC111149705	Vascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (207 aa)
	LOC111149622	Cysteine and glycine-rich protein 3. (194 aa)
	LOC111149447	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
	LOC111146160	Myosin regulatory light chain 10. (167 aa)
	LOC111147545	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC111146078	Gelsolin isoform X1. (782 aa)
	LOC111143787	Myosin light chain 3. (197 aa)
	LOC111144745	LOW QUALITY PROTEIN: ryanodine receptor 2. (5099 aa)
	LOC111143126	Potassium voltage-gated channel subfamily E member 4. (221 aa)
	LOC111143872	Troponin C, slow skeletal and cardiac muscles. (161 aa)
	LOC111143738	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
	LOC111141224	Homeobox protein Nkx-2.5. (323 aa)
	LOC111140065	Troponin I, cardiac muscle isoform X1. (211 aa)
	LOC111141155	Delta-sarcoglycan. (289 aa)
	LOC111141636	Alpha-1-syntrophin. (505 aa)
	LOC111140523	Myosin-6-like. (248 aa)
	LOC111141065	Nuclear pore complex protein Nup155 isoform X1. (1391 aa)
	LOC111141014	Mothers against decapentaplegic homolog. (465 aa)
	LOC111140566	Myosin-7-like. (248 aa)
	LOC111139655	Myosin-6-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (783 aa)
	LOC111139240	Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111139240	LOC111158041	A0A2Y9IFR2	A0A2Y9KW52	Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily.	0.983
LOC111139655	LOC111140065	A0A2Y9IHE2	A0A2Y9IQ49	Myosin-6-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Troponin I, cardiac muscle isoform X1.	0.663
LOC111139655	LOC111140523	A0A2Y9IHE2	A0A2Y9IM86	Myosin-6-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin-6-like.	0.647
LOC111139655	LOC111140566	A0A2Y9IHE2	A0A2Y9IIP1	Myosin-6-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin-7-like.	0.646
LOC111139655	LOC111143787	A0A2Y9IHE2	A0A2Y9J635	Myosin-6-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin light chain 3.	0.808
LOC111139655	LOC111143872	A0A2Y9IHE2	A0A2Y9J1M9	Myosin-6-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Troponin C, slow skeletal and cardiac muscles.	0.443
LOC111139655	LOC111146160	A0A2Y9IHE2	A0A2Y9JHJ6	Myosin-6-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin regulatory light chain 10.	0.545
LOC111139655	LOC111149479	A0A2Y9IHE2	A0A2Y9JXG5	Myosin-6-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Troponin I, fast skeletal muscle.	0.623
LOC111139655	LOC111151081	A0A2Y9IHE2	A0A2Y9JYE3	Myosin-6-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Troponin I, slow skeletal muscle.	0.663
LOC111139655	LOC111151698	A0A2Y9IHE2	A0A2Y9JXI1	Myosin-6-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Telethonin isoform X1.	0.523
LOC111139655	LOC111156317	A0A2Y9IHE2	A0A2Y9KI51	Myosin-6-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform X1.	0.842
LOC111139655	LOC111158127	A0A2Y9IHE2	A0A2Y9KRD4	Myosin-6-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin light chain 4.	0.808
LOC111140065	LOC111139655	A0A2Y9IQ49	A0A2Y9IHE2	Troponin I, cardiac muscle isoform X1.	Myosin-6-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.663
LOC111140065	LOC111140523	A0A2Y9IQ49	A0A2Y9IM86	Troponin I, cardiac muscle isoform X1.	Myosin-6-like.	0.663
LOC111140065	LOC111140566	A0A2Y9IQ49	A0A2Y9IIP1	Troponin I, cardiac muscle isoform X1.	Myosin-7-like.	0.663
LOC111140065	LOC111141224	A0A2Y9IQ49	A0A2Y9ITU2	Troponin I, cardiac muscle isoform X1.	Homeobox protein Nkx-2.5.	0.481
LOC111140065	LOC111143787	A0A2Y9IQ49	A0A2Y9J635	Troponin I, cardiac muscle isoform X1.	Myosin light chain 3.	0.689
LOC111140065	LOC111143872	A0A2Y9IQ49	A0A2Y9J1M9	Troponin I, cardiac muscle isoform X1.	Troponin C, slow skeletal and cardiac muscles.	0.999
LOC111140065	LOC111144745	A0A2Y9IQ49	A0A2Y9J2Y3	Troponin I, cardiac muscle isoform X1.	LOW QUALITY PROTEIN: ryanodine receptor 2.	0.502
LOC111140065	LOC111146160	A0A2Y9IQ49	A0A2Y9JHJ6	Troponin I, cardiac muscle isoform X1.	Myosin regulatory light chain 10.	0.607