(6 nodes) Mammary gland formation network (Enhydra lutris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111157049	Transcriptional activator GLI3. (1585 aa)
	LOC111151576	T-box transcription factor TBX2. (713 aa)
	LOC111145254	Pro-neuregulin-3, membrane-bound isoform isoform X1. (722 aa)
	LOC111141115	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
	LOC111156410	T-box transcription factor TBX3 isoform X1. (744 aa)
	LOC111162047	Bone morphogenetic protein 4 isoform X1. (456 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111141115	LOC111162047	A0A2Y9IT68	A0A2Y9LJR5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4 isoform X1.	0.772
LOC111151576	LOC111157049	A0A2Y9JWF8	A0A2Y9KLI8	T-box transcription factor TBX2.	Transcriptional activator GLI3.	0.434
LOC111156410	LOC111162047	A0A2Y9KNT3	A0A2Y9LJR5	T-box transcription factor TBX3 isoform X1.	Bone morphogenetic protein 4 isoform X1.	0.464
LOC111157049	LOC111151576	A0A2Y9KLI8	A0A2Y9JWF8	Transcriptional activator GLI3.	T-box transcription factor TBX2.	0.434
LOC111162047	LOC111141115	A0A2Y9LJR5	A0A2Y9IT68	Bone morphogenetic protein 4 isoform X1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.772
LOC111162047	LOC111156410	A0A2Y9LJR5	A0A2Y9KNT3	Bone morphogenetic protein 4 isoform X1.	T-box transcription factor TBX3 isoform X1.	0.464