(15 nodes) Metanephric epithelium development network (Enhydra lutris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111158488	Paired box protein Pax-8 isoform X1. (499 aa)
	LOC111158202	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
	LOC111158128	Transcription factor SOX-9 isoform X1. (510 aa)
	LOC111156195	Polycystin-2. (970 aa)
	LOC111156258	Polycystin-1 isoform X3. (4310 aa)
	LOC111156095	Transcription factor SOX-8. (462 aa)
	LOC111155108	Transcription factor HES-1. (281 aa)
	LOC111154575	Transcription factor HES-5. (167 aa)
	LOC111154152	Protein odd-skipped-related 1. (267 aa)
	LOC111150919	Podocin isoform X1. (378 aa)
	LOC111150173	Leucine-rich repeat-containing G-protein coupled receptor 4 isoform X2. (951 aa)
	LOC111149985	Wilms tumor protein isoform X1. (302 aa)
	LOC111147371	Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
	LOC111146691	Calbindin. (261 aa)
	LOC111144053	Laminin subunit beta-2 isoform X1. (1801 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111146691	LOC111158128	A0A2Y9JJR7	A0A2Y9KWM5	Calbindin.	Transcription factor SOX-9 isoform X1.	0.457
LOC111147371	LOC111150919	A0A2Y9JMK7	A0A2Y9K3Q0	Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Podocin isoform X1.	0.428
LOC111149985	LOC111150919	A0A2Y9JQQ2	A0A2Y9K3Q0	Wilms tumor protein isoform X1.	Podocin isoform X1.	0.937
LOC111149985	LOC111156095	A0A2Y9JQQ2	A0A2Y9KM00	Wilms tumor protein isoform X1.	Transcription factor SOX-8.	0.434
LOC111149985	LOC111158128	A0A2Y9JQQ2	A0A2Y9KWM5	Wilms tumor protein isoform X1.	Transcription factor SOX-9 isoform X1.	0.701
LOC111149985	LOC111158202	A0A2Y9JQQ2	A0A2Y9KWZ8	Wilms tumor protein isoform X1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.509
LOC111149985	LOC111158488	A0A2Y9JQQ2	A0A2Y9KY46	Wilms tumor protein isoform X1.	Paired box protein Pax-8 isoform X1.	0.513
LOC111150919	LOC111147371	A0A2Y9K3Q0	A0A2Y9JMK7	Podocin isoform X1.	Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.428
LOC111150919	LOC111149985	A0A2Y9K3Q0	A0A2Y9JQQ2	Podocin isoform X1.	Wilms tumor protein isoform X1.	0.937
LOC111150919	LOC111158488	A0A2Y9K3Q0	A0A2Y9KY46	Podocin isoform X1.	Paired box protein Pax-8 isoform X1.	0.511
LOC111154575	LOC111155108	A0A2Y9K887	A0A2Y9KHC7	Transcription factor HES-5.	Transcription factor HES-1.	0.909
LOC111155108	LOC111154575	A0A2Y9KHC7	A0A2Y9K887	Transcription factor HES-1.	Transcription factor HES-5.	0.909
LOC111156095	LOC111149985	A0A2Y9KM00	A0A2Y9JQQ2	Transcription factor SOX-8.	Wilms tumor protein isoform X1.	0.434
LOC111156195	LOC111156258	A0A2Y9KTZ2	A0A2Y9KN08	Polycystin-2.	Polycystin-1 isoform X3.	0.997
LOC111156258	LOC111156195	A0A2Y9KN08	A0A2Y9KTZ2	Polycystin-1 isoform X3.	Polycystin-2.	0.997
LOC111158128	LOC111146691	A0A2Y9KWM5	A0A2Y9JJR7	Transcription factor SOX-9 isoform X1.	Calbindin.	0.457
LOC111158128	LOC111149985	A0A2Y9KWM5	A0A2Y9JQQ2	Transcription factor SOX-9 isoform X1.	Wilms tumor protein isoform X1.	0.701
LOC111158202	LOC111149985	A0A2Y9KWZ8	A0A2Y9JQQ2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Wilms tumor protein isoform X1.	0.509
LOC111158202	LOC111158488	A0A2Y9KWZ8	A0A2Y9KY46	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Paired box protein Pax-8 isoform X1.	0.603
LOC111158488	LOC111149985	A0A2Y9KY46	A0A2Y9JQQ2	Paired box protein Pax-8 isoform X1.	Wilms tumor protein isoform X1.	0.513