Your Input: | |
| | LOC111147879 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (487 aa) |
| | LOC111148340 | LOW QUALITY PROTEIN: SMC5-SMC6 complex localization factor protein 1. (1058 aa) |
| | LOC111147523 | Bcl-2-associated transcription factor 1 isoform X1. (921 aa) |
| | LOC111148986 | BRCA1-A complex subunit Abraxas 1. (409 aa) |
| | LOC111149436 | Histone-lysine N-methyltransferase KMT5B isoform X1. (885 aa) |
| | LOC111149673 | Cell cycle checkpoint control protein; Belongs to the rad9 family. (390 aa) |
| | LOC111149354 | Helicase POLQ-like isoform X2. (1058 aa) |
| | LOC111150644 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa) |
| | LOC111150788 | Ski-like protein. (684 aa) |
| | LOC111150713 | ATP-dependent RNA helicase A isoform X1. (1284 aa) |
| | LOC111151016 | Ubiquitin carboxyl-terminal hydrolase. (329 aa) |
| | LOC111151280 | Telomere-associated protein RIF1 isoform X1. (2478 aa) |
| | LOC111151497 | Hypermethylated in cancer 1 protein isoform X1. (732 aa) |
| | LOC111151608 | MBT domain-containing protein 1 isoform X1. (630 aa) |
| | LOC111149712 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) |
| | LOC111152447 | Oocyte-expressed protein homolog. (149 aa) |
| | LOC111150530 | wiskott-Aldrich syndrome protein. (501 aa) |
| | LOC111151942 | Inhibitor of growth protein. (418 aa) |
| | LOC111152980 | Protein spire homolog 2. (723 aa) |
| | LOC111153730 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3057 aa) |
| | LOC111154098 | Cell cycle and apoptosis regulator protein 2 isoform X1. (918 aa) |
| | LOC111154412 | PAX-interacting protein 1 isoform X1. (1160 aa) |
| | LOC111154272 | Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa) |
| | LOC111153711 | Nuclear factor related to kappa-B-binding protein isoform X1. (1311 aa) |
| | LOC111154697 | Mitotic spindle assembly checkpoint protein MAD2B. (211 aa) |
| | LOC111152471 | KHDC3-like protein. (287 aa) |
| | LOC111155054 | E3 ubiquitin-protein ligase DTX3L. (745 aa) |
| | LOC111155419 | Lymphokine-activated killer T-cell-originated protein kinase isoform X2. (323 aa) |
| | LOC111155373 | DNA repair-scaffolding protein isoform X1. (698 aa) |
| | LOC111155437 | Ubiquitin-conjugating enzyme E2 variant 2 isoform X1. (145 aa) |
| | LOC111155857 | Protein FAM178B. (553 aa) |
| | LOC111155027 | Poly [ADP-ribose] polymerase. (825 aa) |
| | LOC111156502 | B-cell CLL/lymphoma 7 protein family member A isoform X1. (231 aa) |
| | LOC111153902 | High mobility group protein B1. (215 aa) |
| | LOC111155445 | DNA-dependent protein kinase catalytic subunit isoform X1; Belongs to the PI3/PI4-kinase family. (4134 aa) |
| | LOC111156750 | Eukaryotic translation elongation factor 1 epsilon-1 isoform X1. (187 aa) |
| | LOC111156802 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa) |
| | LOC111157042 | Receptor protein-tyrosine kinase. (1154 aa) |
| | LOC111156946 | DNA excision repair protein ERCC-8 isoform X1. (400 aa) |
| | LOC111157180 | Fanconi anemia group B protein. (865 aa) |
| | LOC111157974 | Zinc finger protein 385A isoform X1. (386 aa) |
| | LOC111162339 | B-cell CLL/lymphoma 7 protein family member C isoform X1. (242 aa) |
| | LOC111161301 | Mortality factor 4-like protein 2. (288 aa) |
| | LOC111162000 | Vacuolar protein sorting-associated protein 72 homolog isoform X1. (374 aa) |
| | LOC111161542 | CCAAT/enhancer-binding protein gamma. (146 aa) |
| | LOC111162297 | Non-structural maintenance of chromosomes element 1 homolog isoform X1. (283 aa) |
| | LOC111162225 | RNA-binding protein FUS isoform X1. (517 aa) |
| | LOC111157850 | AT-rich interactive domain-containing protein 2. (1836 aa) |
| | LOC111142446 | DNA endonuclease RBBP8. (897 aa) |
| | LOC111142165 | Secretory phospholipase A2 receptor. (1463 aa) |
| | LOC111142431 | Structural maintenance of chromosomes flexible hinge domain-containing protein 1 isoform X1. (2002 aa) |
| | LOC111142469 | Protein spire homolog 1 isoform X1. (752 aa) |
| | LOC111141843 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | LOC111141115 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | LOC111143046 | DNA methyltransferase 1-associated protein 1. (468 aa) |
| | LOC111143064 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (572 aa) |
| | LOC111143430 | Chromatin modification-related protein MEAF6 isoform X1. (201 aa) |
| | LOC111143469 | Mitogen-activated protein kinase kinase kinase 20 isoform X1. (800 aa) |
| | LOC111143793 | Enhancer of polycomb homolog. (807 aa) |
| | LOC111143923 | Transmembrane protein 161A isoform X1. (480 aa) |
| | LOC111144236 | BRISC and BRCA1-A complex member 1. (336 aa) |
| | LOC111142835 | LOW QUALITY PROTEIN: protein FAM178B-like. (104 aa) |
| | LOC111144938 | Ankyrin repeat domain-containing protein 1. (382 aa) |
| | LOC111144824 | MMS19 nucleotide excision repair protein homolog isoform X1. (1030 aa) |
| | LOC111144299 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa) |
| | LOC111144328 | Poly [ADP-ribose] polymerase. (531 aa) |
| | LOC111145159 | NAD-dependent protein deacetylase sirtuin-1 isoform X1. (751 aa) |
| | LOC111144441 | TELO2-interacting protein 2 isoform X1. (508 aa) |
| | LOC111145261 | Protein FAM35A isoform X1. (906 aa) |
| | LOC111145543 | Endonuclease. (301 aa) |
| | LOC111145575 | Zinc finger HIT domain-containing protein 1 isoform X1. (191 aa) |
| | LOC111145107 | SMC5-SMC6 complex localization factor protein 2 isoform X1. (1173 aa) |
| | LOC111145842 | Zinc finger CW-type PWWP domain protein 1. (450 aa) |
| | LOC111144122 | Ankyrin repeat and LEM domain-containing protein 1 isoform X1. (620 aa) |
| | LOC111145313 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (385 aa) |
| | LOC111146068 | Nucleus accumbens-associated protein 2. (586 aa) |
| | LOC111146783 | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | LOC111145130 | DNA excision repair protein ERCC-6. (1482 aa) |
| | LOC111147481 | Fragile X mental retardation syndrome-related protein 1 isoform X1. (650 aa) |
| | LOC111147364 | Serine/threonine-protein kinase ATR isoform X1; Belongs to the PI3/PI4-kinase family. (2644 aa) |
| | LOC111147636 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (610 aa) |
| | LOC111161175 | Fragile X mental retardation syndrome-related protein 2. (673 aa) |
| | LOC111162214 | LOW QUALITY PROTEIN: INO80 complex subunit E. (244 aa) |
| | LOC111159826 | Inhibitor of growth protein. (249 aa) |
| | LOC111162011 | Pogo transposable element with ZNF domain isoform X1. (1414 aa) |
| | LOC111161831 | NAD-dependent protein deacetylase sirtuin-6 isoform X1. (359 aa) |
| | LOC111159396 | Protein FAM168A isoform X1. (244 aa) |
| | LOC111159085 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | LOC111158924 | DNA helicase INO80 isoform X1. (1561 aa) |
| | LOC111161688 | E3 SUMO-protein ligase PIAS4. (512 aa) |
| | LOC111161213 | Telomerase Cajal body protein 1. (532 aa) |
| | LOC111161699 | Hepatoma-derived growth factor-related protein 2 isoform X1. (672 aa) |
| | LOC111159775 | RAD51-associated protein 1 isoform X2. (353 aa) |
| | LOC111160596 | Bifunctional polynucleotide phosphatase/kinase. (521 aa) |
| | LOC111160659 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | LOC111157572 | Histone deacetylase 10 isoform X1. (724 aa) |
| | LOC111160404 | UNC93-like protein MFSD11 isoform X1. (449 aa) |
| | LOC111160357 | Sprouty-related, EVH1 domain-containing protein 1 isoform X1. (456 aa) |
| | LOC111160224 | Protein timeless homolog isoform X1. (1209 aa) |
| | LOC111160087 | Coiled-coil domain-containing protein 117 isoform X1. (277 aa) |
| | LOC111156657 | Homeobox protein Nkx-3.1. (229 aa) |
| | LOC111159164 | WD repeat-containing protein 48 isoform X1. (677 aa) |
| | LOC111159814 | Forkhead box protein M1 isoform X3. (762 aa) |
| | LOC111159813 | Fructose-2,6-bisphosphatase TIGAR isoform X1. (270 aa) |
| | LOC111157944 | Microspherule protein 1 isoform X1. (475 aa) |
| | LOC111159428 | 40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | LOC111158949 | Synaptic functional regulator FMR1 isoform X1. (632 aa) |
| | LOC111158109 | Probable ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (614 aa) |
| | LOC111158854 | MRN complex-interacting protein isoform X1. (335 aa) |
| | LOC111158603 | F-box DNA helicase 1. (1045 aa) |
| | LOC111155572 | Enhancer of polycomb homolog. (842 aa) |
| | LOC111155172 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (572 aa) |
| | LOC111139192 | Lys-63-specific deubiquitinase BRCC36 isoform X1. (316 aa) |
| | LOC111139277 | BRISC and BRCA1-A complex member 2. (383 aa) |
| | LOC111139563 | TCF3 fusion partner. (253 aa) |
| | LOC111139613 | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | LOC111139579 | Histone-lysine N-methyltransferase KMT5C isoform X1. (459 aa) |
| | LOC111139850 | Transcription intermediary factor 1-beta isoform X2. (835 aa) |
| | LOC111140494 | High mobility group protein B1-like. (141 aa) |
| | LOC111140003 | E1A-binding protein p400. (3074 aa) |
| | LOC111140827 | Bromodomain-containing protein 8 isoform X1. (1277 aa) |
| | LOC111141593 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (538 aa) |
| | LOC111139524 | DNA repair protein XRCC1 isoform X1. (630 aa) |
| | LOC111141698 | Uncharacterized protein C20orf196 homolog. (206 aa) |
| | LOC111141599 | MRG/MORF4L-binding protein. (202 aa) |
| | LOC111141182 | BRCA1-A complex subunit RAP80. (721 aa) |
| | LOC111142083 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (369 aa) |
| | LOC111141980 | YEATS domain-containing protein 4 isoform X1. (227 aa) |
| | LOC111141970 | INO80 complex subunit D. (1029 aa) |
