(10 nodes) Alpha crystallin/Hsp20 domain network (Enhydra lutris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111151714	Heat shock protein beta-9; Belongs to the small heat shock protein (HSP20) family. (162 aa)
	LOC111145764	Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (207 aa)
	LOC111155751	Alpha-crystallin A chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (173 aa)
	LOC111141128	Heat shock protein beta-3; Belongs to the small heat shock protein (HSP20) family. (150 aa)
	LOC111161508	Heat shock protein beta-6; Belongs to the small heat shock protein (HSP20) family. (163 aa)
	LOC111156505	Heat shock protein beta-8; Belongs to the small heat shock protein (HSP20) family. (196 aa)
	LOC111154776	Heat shock protein beta-7 isoform X2; Belongs to the small heat shock protein (HSP20) family. (178 aa)
	LOC111153702	Alpha-crystallin B chain isoform X1; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
	LOC111153701	Heat shock protein beta-2; Belongs to the small heat shock protein (HSP20) family. (182 aa)
	LOC111146615	Outer dense fiber protein 1. (246 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111141128	LOC111151714	A0A2Y9IKI6	A0A2Y9K1H9	Heat shock protein beta-3; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-9; Belongs to the small heat shock protein (HSP20) family.	0.728
LOC111141128	LOC111153701	A0A2Y9IKI6	A0A2Y9K628	Heat shock protein beta-3; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-2; Belongs to the small heat shock protein (HSP20) family.	0.868
LOC111141128	LOC111154776	A0A2Y9IKI6	A0A2Y9KFX5	Heat shock protein beta-3; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-7 isoform X2; Belongs to the small heat shock protein (HSP20) family.	0.740
LOC111141128	LOC111156505	A0A2Y9IKI6	A0A2Y9KH52	Heat shock protein beta-3; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-8; Belongs to the small heat shock protein (HSP20) family.	0.508
LOC111145764	LOC111153702	A0A2Y9JAE6	A0A2Y9KAE5	Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family.	Alpha-crystallin B chain isoform X1; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.	0.734
LOC111145764	LOC111156505	A0A2Y9JAE6	A0A2Y9KH52	Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-8; Belongs to the small heat shock protein (HSP20) family.	0.559
LOC111145764	LOC111161508	A0A2Y9JAE6	A0A2Y9LGZ9	Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-6; Belongs to the small heat shock protein (HSP20) family.	0.412
LOC111151714	LOC111141128	A0A2Y9K1H9	A0A2Y9IKI6	Heat shock protein beta-9; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-3; Belongs to the small heat shock protein (HSP20) family.	0.728
LOC111151714	LOC111153701	A0A2Y9K1H9	A0A2Y9K628	Heat shock protein beta-9; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-2; Belongs to the small heat shock protein (HSP20) family.	0.608
LOC111151714	LOC111154776	A0A2Y9K1H9	A0A2Y9KFX5	Heat shock protein beta-9; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-7 isoform X2; Belongs to the small heat shock protein (HSP20) family.	0.604
LOC111151714	LOC111155751	A0A2Y9K1H9	A0A2Y9KEB2	Heat shock protein beta-9; Belongs to the small heat shock protein (HSP20) family.	Alpha-crystallin A chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.	0.426
LOC111151714	LOC111156505	A0A2Y9K1H9	A0A2Y9KH52	Heat shock protein beta-9; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-8; Belongs to the small heat shock protein (HSP20) family.	0.511
LOC111151714	LOC111161508	A0A2Y9K1H9	A0A2Y9LGZ9	Heat shock protein beta-9; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-6; Belongs to the small heat shock protein (HSP20) family.	0.515
LOC111153701	LOC111141128	A0A2Y9K628	A0A2Y9IKI6	Heat shock protein beta-2; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-3; Belongs to the small heat shock protein (HSP20) family.	0.868
LOC111153701	LOC111151714	A0A2Y9K628	A0A2Y9K1H9	Heat shock protein beta-2; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-9; Belongs to the small heat shock protein (HSP20) family.	0.608
LOC111153701	LOC111153702	A0A2Y9K628	A0A2Y9KAE5	Heat shock protein beta-2; Belongs to the small heat shock protein (HSP20) family.	Alpha-crystallin B chain isoform X1; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.	0.677
LOC111153701	LOC111154776	A0A2Y9K628	A0A2Y9KFX5	Heat shock protein beta-2; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-7 isoform X2; Belongs to the small heat shock protein (HSP20) family.	0.545
LOC111153701	LOC111156505	A0A2Y9K628	A0A2Y9KH52	Heat shock protein beta-2; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-8; Belongs to the small heat shock protein (HSP20) family.	0.447
LOC111153702	LOC111145764	A0A2Y9KAE5	A0A2Y9JAE6	Alpha-crystallin B chain isoform X1; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.	Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family.	0.734
LOC111153702	LOC111153701	A0A2Y9KAE5	A0A2Y9K628	Alpha-crystallin B chain isoform X1; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.	Heat shock protein beta-2; Belongs to the small heat shock protein (HSP20) family.	0.677