(21 nodes) Aspartic peptidase domain superfamily network (Enhydra lutris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111162260	LOW QUALITY PROTEIN: uncharacterized protein LOC111162260. (1716 aa)
	LOC111143434	Chymosin-like; Belongs to the peptidase A1 family. (381 aa)
	LOC111147939	Retroviral-like aspartic protease 1. (259 aa)
	LOC111148751	Retrotransposon-like protein 1. (1329 aa)
	LOC111147308	LOW QUALITY PROTEIN: retrotransposon-derived protein PEG10. (794 aa)
	LOC111147505	Gastricsin; Belongs to the peptidase A1 family. (389 aa)
	LOC111149567	Cathepsin D; Belongs to the peptidase A1 family. (410 aa)
	LOC111150016	Pepsin A; Belongs to the peptidase A1 family. (386 aa)
	LOC111151146	Renin; Belongs to the peptidase A1 family. (404 aa)
	LOC111151129	Cathepsin E; Belongs to the peptidase A1 family. (397 aa)
	LOC111150162	Pepsin F-like; Belongs to the peptidase A1 family. (388 aa)
	LOC111153782	Protein DDI1 homolog 1. (400 aa)
	LOC111154635	Regulatory solute carrier protein family 1 member 1 isoform X1. (1018 aa)
	LOC111153672	Beta-secretase 1 isoform X1; Belongs to the peptidase A1 family. (501 aa)
	LOC111155523	LOW QUALITY PROTEIN: uncharacterized protein LOC111155523. (1576 aa)
	LOC111155713	Beta-secretase 2 isoform X1; Belongs to the peptidase A1 family. (511 aa)
	LOC111159526	Nuclear receptor-interacting protein 3. (240 aa)
	LOC111159749	Nuclear receptor-interacting protein 2. (253 aa)
	LOC111160829	napsin-A; Belongs to the peptidase A1 family. (424 aa)
	LOC111142948	LOW QUALITY PROTEIN: pepsin B-like; Belongs to the peptidase A1 family. (390 aa)
	LOC111142951	Pepsin B-like; Belongs to the peptidase A1 family. (390 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111150016	LOC111150162	A0A2Y9JPL9	A0A2Y9K0J2	Pepsin A; Belongs to the peptidase A1 family.	Pepsin F-like; Belongs to the peptidase A1 family.	0.902
LOC111150162	LOC111150016	A0A2Y9K0J2	A0A2Y9JPL9	Pepsin F-like; Belongs to the peptidase A1 family.	Pepsin A; Belongs to the peptidase A1 family.	0.902
LOC111153672	LOC111155713	A0A2Y9KAB3	A0A2Y9KD89	Beta-secretase 1 isoform X1; Belongs to the peptidase A1 family.	Beta-secretase 2 isoform X1; Belongs to the peptidase A1 family.	0.901
LOC111153782	LOC111159526	A0A2Y9K551	A0A2Y9KUQ9	Protein DDI1 homolog 1.	Nuclear receptor-interacting protein 3.	0.435
LOC111155713	LOC111153672	A0A2Y9KD89	A0A2Y9KAB3	Beta-secretase 2 isoform X1; Belongs to the peptidase A1 family.	Beta-secretase 1 isoform X1; Belongs to the peptidase A1 family.	0.901
LOC111159526	LOC111153782	A0A2Y9KUQ9	A0A2Y9K551	Nuclear receptor-interacting protein 3.	Protein DDI1 homolog 1.	0.435