37 items (Enhydra lutris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111140421	Guanine nucleotide-binding protein subunit beta-5. (353 aa)
	LOC111140965	Phosphodiesterase. (861 aa)
	LOC111142046	Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma. (83 aa)
	LOC111142101	Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. (478 aa)
	LOC111142058	Vezatin isoform X1. (794 aa)
	LOC111142883	S-arrestin isoform X1. (405 aa)
	LOC111144021	Guanine nucleotide-binding protein G(T) subunit alpha-1. (350 aa)
	LOC111144545	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha. (379 aa)
	LOC111144918	Phosphodiesterase. (845 aa)
	LOC111144037	Rhodopsin. (348 aa)
	LOC111147281	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	LOC111147473	Guanylyl cyclase-activating protein 2 isoform X1. (251 aa)
	LOC111147107	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (564 aa)
	LOC111148494	Calmodulin-1 isoform X1; Belongs to the calmodulin family. (196 aa)
	LOC111147844	Guanylyl cyclase-activating protein 1. (204 aa)
	LOC111146742	LOW QUALITY PROTEIN: cyclic nucleotide-gated cation channel beta-3. (806 aa)
	LOC111146915	Guanylyl cyclase-activating protein 3. (203 aa)
	LOC111149226	cGMP-gated cation channel alpha-1. (694 aa)
	LOC111149116	Serine/threonine-protein phosphatase with EF-hands. (737 aa)
	LOC111149075	Phosphodiesterase. (856 aa)
	LOC111150527	Serine/threonine-protein phosphatase with EF-hands. (661 aa)
	LOC111151154	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (553 aa)
	LOC111155544	Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (498 aa)
	LOC111155906	Calmodulin-lysine N-methyltransferase. (323 aa)
	LOC111157412	Cyclic nucleotide-gated cation channel beta-1. (1209 aa)
	LOC111158076	Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (496 aa)
	LOC111158098	Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. (437 aa)
	LOC111158606	Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
	LOC111157617	Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). (386 aa)
	LOC111159348	Guanylate cyclase. (1093 aa)
	LOC111158129	Protein Churchill isoform X1. (112 aa)
	LOC111160977	Guanylate cyclase. (1123 aa)
	LOC111158118	Regulator of G-protein signaling 9 isoform X1. (678 aa)
	LOC111160255	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma. (87 aa)
	LOC111161620	Regulator of G-protein signaling 9-binding protein. (237 aa)
	LOC111161107	Recoverin. (202 aa)
	LOC111161167	Guanylate cyclase. (1109 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111140421	LOC111144021	A0A2Y9IIA6	A0A2Y9IYX7	Guanine nucleotide-binding protein subunit beta-5.	Guanine nucleotide-binding protein G(T) subunit alpha-1.	0.755
LOC111140421	LOC111144037	A0A2Y9IIA6	A0A2Y9J7G3	Guanine nucleotide-binding protein subunit beta-5.	Rhodopsin.	0.776
LOC111140421	LOC111147107	A0A2Y9IIA6	A0A2Y9JGC3	Guanine nucleotide-binding protein subunit beta-5.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.532
LOC111140421	LOC111147281	A0A2Y9IIA6	A0A2Y9JD27	Guanine nucleotide-binding protein subunit beta-5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.756
LOC111140421	LOC111149075	A0A2Y9IIA6	A0A2Y9JQ56	Guanine nucleotide-binding protein subunit beta-5.	Phosphodiesterase.	0.484
LOC111140421	LOC111151154	A0A2Y9IIA6	A0A2Y9JYR6	Guanine nucleotide-binding protein subunit beta-5.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.533
LOC111140421	LOC111158118	A0A2Y9IIA6	A0A2Y9L2I1	Guanine nucleotide-binding protein subunit beta-5.	Regulator of G-protein signaling 9 isoform X1.	0.965
LOC111140421	LOC111160255	A0A2Y9IIA6	A0A2Y9L5M2	Guanine nucleotide-binding protein subunit beta-5.	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma.	0.490
LOC111140421	LOC111161620	A0A2Y9IIA6	A0A2Y9L6X7	Guanine nucleotide-binding protein subunit beta-5.	Regulator of G-protein signaling 9-binding protein.	0.959
LOC111140965	LOC111142046	A0A2Y9IJY1	A0A2Y9IQ83	Phosphodiesterase.	Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma.	0.686
LOC111140965	LOC111144021	A0A2Y9IJY1	A0A2Y9IYX7	Phosphodiesterase.	Guanine nucleotide-binding protein G(T) subunit alpha-1.	0.999
LOC111140965	LOC111144037	A0A2Y9IJY1	A0A2Y9J7G3	Phosphodiesterase.	Rhodopsin.	0.568
LOC111140965	LOC111146742	A0A2Y9IJY1	A0A2Y9JJW0	Phosphodiesterase.	LOW QUALITY PROTEIN: cyclic nucleotide-gated cation channel beta-3.	0.567
LOC111140965	LOC111147107	A0A2Y9IJY1	A0A2Y9JGC3	Phosphodiesterase.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.532
LOC111140965	LOC111147281	A0A2Y9IJY1	A0A2Y9JD27	Phosphodiesterase.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.953
LOC111140965	LOC111147473	A0A2Y9IJY1	A0A2Y9JF46	Phosphodiesterase.	Guanylyl cyclase-activating protein 2 isoform X1.	0.533
LOC111140965	LOC111149075	A0A2Y9IJY1	A0A2Y9JQ56	Phosphodiesterase.	Phosphodiesterase.	0.999
LOC111140965	LOC111149226	A0A2Y9IJY1	A0A2Y9JLR4	Phosphodiesterase.	cGMP-gated cation channel alpha-1.	0.572
LOC111140965	LOC111157412	A0A2Y9IJY1	A0A2Y9KLI0	Phosphodiesterase.	Cyclic nucleotide-gated cation channel beta-1.	0.660
LOC111140965	LOC111158118	A0A2Y9IJY1	A0A2Y9L2I1	Phosphodiesterase.	Regulator of G-protein signaling 9 isoform X1.	0.441