79 items (Enhydra lutris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111156450	Ubiquitin. (82 aa)
	LOC111157341	Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1013 aa)
	LOC111156390	Ubiquitin-conjugating enzyme E2 variant 1-like isoform X1. (148 aa)
	LOC111157625	Mitogen-activated protein kinase. (364 aa)
	LOC111157725	Cyclic AMP-dependent transcription factor ATF-7 isoform X1. (505 aa)
	LOC111155345	LOW QUALITY PROTEIN: coiled-coil domain-containing protein 71L. (237 aa)
	LOC111158801	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
	LOC111157964	Cyclic AMP-dependent transcription factor ATF-1 isoform X1. (329 aa)
	LOC111158041	Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (334 aa)
	LOC111159730	Interleukin-17 receptor A isoform X1. (863 aa)
	LOC111158117	Ubiquitin-conjugating enzyme E2 N-like. (132 aa)
	LOC111158168	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
	LOC111157505	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (504 aa)
	LOC111158720	Ribosomal protein S6 kinase. (733 aa)
	LOC111158897	Mitogen-activated protein kinase 9 isoform X1. (443 aa)
	LOC111161723	Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
	LOC111160740	Inactive serine/threonine-protein kinase VRK3. (455 aa)
	LOC111161210	Dual specificity mitogen-activated protein kinase kinase 4 isoform X2; Belongs to the protein kinase superfamily. (411 aa)
	LOC111162236	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (372 aa)
	LOC111160772	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1. (590 aa)
	LOC111144543	Serine/threonine-protein phosphatase. (309 aa)
	LOC111144273	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)
	LOC111144038	Interleukin-1 receptor-associated kinase-like 2 isoform X1. (618 aa)
	LOC111142235	Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	LOC111143740	Interleukin-17 receptor B isoform X2. (494 aa)
	LOC111143803	kxDL motif-containing protein 1 isoform X1. (184 aa)
	LOC111142759	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
	LOC111143469	Mitogen-activated protein kinase kinase kinase 20 isoform X1. (800 aa)
	LOC111143174	Transcription factor AP-1; Belongs to the bZIP family. (334 aa)
	LOC111142444	Serine/threonine-protein phosphatase 4 regulatory subunit 1 isoform X1. (949 aa)
	LOC111142278	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
	LOC111141428	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like. (893 aa)
	LOC111141412	Ubiquitin-conjugating enzyme E2 variant 1. (147 aa)
	LOC111141316	ubiquitin-60S ribosomal protein L40-like isoform X1. (126 aa)
	LOC111139294	Fos-related antigen 2 isoform X1. (325 aa)
	LOC111140588	Interleukin-25. (169 aa)
	LOC111141024	Serine/threonine-protein phosphatase. (309 aa)
	LOC111139240	Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
	LOC111139471	LOW QUALITY PROTEIN: polyubiquitin-B. (228 aa)
	LOC111139191	NF-kappa-B essential modulator. (412 aa)
	LOC111139244	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (812 aa)
	LOC111139109	Interleukin-1 receptor-associated kinase 1 isoform X3. (729 aa)
	LOC111148602	Proto-oncogene c-Fos. (380 aa)
	LOC111148567	Ribosomal protein S6 kinase. (798 aa)
	LOC111150586	ETS domain-containing protein Elk-1 isoform X1. (484 aa)
	LOC111150506	TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1. (715 aa)
	LOC111150451	Ribosomal protein S6 kinase. (740 aa)
	LOC111150027	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
	LOC111148948	TNFAIP3-interacting protein 2 isoform X1. (435 aa)
	LOC111148645	Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1. (873 aa)
	LOC111148109	ubiquitin-40S ribosomal protein S27a. (156 aa)
	LOC111148280	Ubiquitin-like isoform X1. (137 aa)
	LOC111151153	MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (403 aa)
	LOC111149561	Formin-binding protein 4 isoform X1. (1017 aa)
	LOC111152183	Mitogen-activated protein kinase. (360 aa)
	LOC111152476	interleukin-17A. (153 aa)
	LOC111152749	LOW QUALITY PROTEIN: interleukin-17C. (222 aa)
	LOC111152499	interleukin-17F. (158 aa)
	LOC111154016	Mitogen-activated protein kinase. (464 aa)
	LOC111153735	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2. (663 aa)
	LOC111155540	cAMP-responsive element modulator-like isoform X1. (149 aa)
	LOC111154240	lisH domain and HEAT repeat-containing protein KIAA1468 homolog isoform X3. (1222 aa)
	LOC111154593	Ribosomal protein S6 kinase. (744 aa)
	LOC111149973	Ribosomal protein S6 kinase. (804 aa)
	LOC111147753	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (676 aa)
	LOC111147575	Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
	LOC111147521	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
	LOC111146577	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
	LOC111147440	Nucleotide-binding oligomerization domain-containing protein 1. (953 aa)
	LOC111147321	Cyclic AMP-responsive element-binding protein 5. (501 aa)
	LOC111146788	Mitogen-activated protein kinase. (559 aa)
	LOC111144154	MAP kinase-activated protein kinase 3 isoform X1; Belongs to the protein kinase superfamily. (384 aa)
	LOC111143994	Interleukin-17 receptor C. (713 aa)
	LOC111143805	ubiquitin-60S ribosomal protein L40 isoform X1. (156 aa)
	LOC111144860	Mitogen-activated protein kinase. (427 aa)
	LOC111143970	Interleukin-17 receptor E. (682 aa)
	LOC111144514	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
	LOC111142901	Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
	LOC111154816	ubiquitin-60S ribosomal protein L40-like. (98 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111139109	LOC111139191	A0A2Y9IF24	A0A2Y9IFI7	Interleukin-1 receptor-associated kinase 1 isoform X3.	NF-kappa-B essential modulator.	0.979
LOC111139109	LOC111139240	A0A2Y9IF24	A0A2Y9IFR2	Interleukin-1 receptor-associated kinase 1 isoform X3.	Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	0.488
LOC111139109	LOC111139471	A0A2Y9IF24	A0A2Y9IFL8	Interleukin-1 receptor-associated kinase 1 isoform X3.	LOW QUALITY PROTEIN: polyubiquitin-B.	0.560
LOC111139109	LOC111141024	A0A2Y9IF24	A0A2Y9IK68	Interleukin-1 receptor-associated kinase 1 isoform X3.	Serine/threonine-protein phosphatase.	0.932
LOC111139109	LOC111141412	A0A2Y9IF24	A0A2Y9IN71	Interleukin-1 receptor-associated kinase 1 isoform X3.	Ubiquitin-conjugating enzyme E2 variant 1.	0.432
LOC111139109	LOC111142235	A0A2Y9IF24	A0A2Y9IYI2	Interleukin-1 receptor-associated kinase 1 isoform X3.	Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.	0.587
LOC111139109	LOC111143469	A0A2Y9IF24	A0A2Y9IWE3	Interleukin-1 receptor-associated kinase 1 isoform X3.	Mitogen-activated protein kinase kinase kinase 20 isoform X1.	0.537
LOC111139109	LOC111144038	A0A2Y9IF24	A0A2Y9IZN3	Interleukin-1 receptor-associated kinase 1 isoform X3.	Interleukin-1 receptor-associated kinase-like 2 isoform X1.	0.986
LOC111139109	LOC111144543	A0A2Y9IF24	A0A2Y9J139	Interleukin-1 receptor-associated kinase 1 isoform X3.	Serine/threonine-protein phosphatase.	0.932
LOC111139109	LOC111146577	A0A2Y9IF24	A0A2Y9JDY7	Interleukin-1 receptor-associated kinase 1 isoform X3.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.546
LOC111139109	LOC111147440	A0A2Y9IF24	A0A2Y9JDS1	Interleukin-1 receptor-associated kinase 1 isoform X3.	Nucleotide-binding oligomerization domain-containing protein 1.	0.488
LOC111139109	LOC111147521	A0A2Y9IF24	A0A2Y9JE02	Interleukin-1 receptor-associated kinase 1 isoform X3.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2.	0.998
LOC111139109	LOC111148109	A0A2Y9IF24	A0A2Y9JKU0	Interleukin-1 receptor-associated kinase 1 isoform X3.	ubiquitin-40S ribosomal protein S27a.	0.507
LOC111139109	LOC111150027	A0A2Y9IF24	A0A2Y9JQV9	Interleukin-1 receptor-associated kinase 1 isoform X3.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.999
LOC111139109	LOC111150506	A0A2Y9IF24	A0A2Y9JRP9	Interleukin-1 receptor-associated kinase 1 isoform X3.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1.	0.979
LOC111139109	LOC111153735	A0A2Y9IF24	A0A2Y9K698	Interleukin-1 receptor-associated kinase 1 isoform X3.	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2.	0.918
LOC111139109	LOC111156390	A0A2Y9IF24	A0A2Y9KNN4	Interleukin-1 receptor-associated kinase 1 isoform X3.	Ubiquitin-conjugating enzyme E2 variant 1-like isoform X1.	0.432
LOC111139109	LOC111157341	A0A2Y9IF24	A0A2Y9KL71	Interleukin-1 receptor-associated kinase 1 isoform X3.	Nucleotide-binding oligomerization domain-containing protein 2 isoform X1.	0.621
LOC111139109	LOC111157505	A0A2Y9IF24	A0A2Y9KZR2	Interleukin-1 receptor-associated kinase 1 isoform X3.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1.	0.978
LOC111139109	LOC111158041	A0A2Y9IF24	A0A2Y9KW52	Interleukin-1 receptor-associated kinase 1 isoform X3.	Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily.	0.423