STRINGSTRING
LOC111156102 LOC111156102 LOC111139701 LOC111139701 LOC111139155 LOC111139155 LOC111144982 LOC111144982 LOC111145181 LOC111145181 LOC111148133 LOC111148133 LOC111148494 LOC111148494 LOC111148677 LOC111148677 LOC111149130 LOC111149130 LOC111148949 LOC111148949 LOC111148765 LOC111148765 LOC111153903 LOC111153903 LOC111154402 LOC111154402 LOC111156109 LOC111156109 LOC111156431 LOC111156431 LOC111157390 LOC111157390 LOC111158606 LOC111158606 LOC111158079 LOC111158079 LOC111158280 LOC111158280 LOC111158309 LOC111158309 LOC111161374 LOC111161374
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC1111561025-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (230 aa)
LOC111139701Decaprenyl-diphosphate synthase subunit 1 isoform X3; Belongs to the FPP/GGPP synthase family. (420 aa)
LOC111139155GTP cyclohydrolase 1 isoform X1. (249 aa)
LOC111144982Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
LOC111145181Inositol 1,4,5-trisphosphate receptor-interacting protein isoform X1. (601 aa)
LOC111148133Sepiapterin reductase. (267 aa)
LOC111148494Calmodulin-1 isoform X1; Belongs to the calmodulin family. (196 aa)
LOC111148677Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (469 aa)
LOC111149130cGMP-dependent protein kinase. (762 aa)
LOC1111489494-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (369 aa)
LOC111148765Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC1111539036-pyruvoyl tetrahydrobiopterin synthase. (147 aa)
LOC111154402Nitric oxide synthase; Produces nitric oxide (NO). (1211 aa)
LOC111156109Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2. (532 aa)
LOC1111564312-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (327 aa)
LOC111157390Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (322 aa)
LOC111158606Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
LOC111158079GTP cyclohydrolase 1 feedback regulatory protein. (84 aa)
LOC111158280Decaprenyl-diphosphate synthase subunit 2 isoform X1; Belongs to the FPP/GGPP synthase family. (400 aa)
LOC111158309Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (367 aa)
LOC111161374Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
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