STRINGSTRING
LOC111138962 LOC111138962 LOC111139074 LOC111139074 LOC111139613 LOC111139613 LOC111140316 LOC111140316 LOC111141024 LOC111141024 LOC111141620 LOC111141620 LOC111142435 LOC111142435 LOC111141782 LOC111141782 LOC111141432 LOC111141432 LOC111142759 LOC111142759 LOC111143470 LOC111143470 LOC111138525 LOC111138525 LOC111143783 LOC111143783 LOC111143790 LOC111143790 LOC111143048 LOC111143048 LOC111143238 LOC111143238 LOC111143343 LOC111143343 LOC111144026 LOC111144026 LOC111144322 LOC111144322 LOC111144244 LOC111144244 LOC111144543 LOC111144543 LOC111144778 LOC111144778 LOC111144609 LOC111144609 LOC111144860 LOC111144860 LOC111144887 LOC111144887 LOC111143159 LOC111143159 LOC111145250 LOC111145250 LOC111145321 LOC111145321 LOC111145572 LOC111145572 LOC111146098 LOC111146098 LOC111146100 LOC111146100 LOC111145636 LOC111145636 LOC111145303 LOC111145303 LOC111147502 LOC111147502 LOC111145476 LOC111145476 LOC111147545 LOC111147545 LOC111147753 LOC111147753 LOC111148688 LOC111148688 LOC111148624 LOC111148624 LOC111148709 LOC111148709 LOC111149174 LOC111149174 LOC111148513 LOC111148513 LOC111148765 LOC111148765 LOC111149567 LOC111149567 LOC111148821 LOC111148821 LOC111149986 LOC111149986 LOC111150005 LOC111150005 LOC111150191 LOC111150191 LOC111150885 LOC111150885 LOC111150825 LOC111150825 LOC111151074 LOC111151074 LOC111150121 LOC111150121 LOC111149390 LOC111149390 LOC111152183 LOC111152183 LOC111152267 LOC111152267 LOC111149956 LOC111149956 LOC111152682 LOC111152682 LOC111150668 LOC111150668 LOC111152248 LOC111152248 LOC111153611 LOC111153611 LOC111153496 LOC111153496 LOC111153498 LOC111153498 LOC111154016 LOC111154016 LOC111153735 LOC111153735 LOC111152832 LOC111152832 LOC111154409 LOC111154409 LOC111153158 LOC111153158 LOC111154402 LOC111154402 LOC111154565 LOC111154565 LOC111155025 LOC111155025 LOC111155003 LOC111155003 LOC111154090 LOC111154090 LOC111155312 LOC111155312 LOC111155379 LOC111155379 LOC111155859 LOC111155859 LOC111154641 LOC111154641 LOC111156238 LOC111156238 LOC111153624 LOC111153624 LOC111154217 LOC111154217 LOC111157091 LOC111157091 LOC111154506 LOC111154506 LOC111156936 LOC111156936 LOC111157484 LOC111157484 LOC111157064 LOC111157064 LOC111158131 LOC111158131 LOC111157625 LOC111157625 LOC111155224 LOC111155224 LOC111157957 LOC111157957 LOC111156293 LOC111156293 LOC111157628 LOC111157628 LOC111156598 LOC111156598 LOC111159912 LOC111159912 LOC111158087 LOC111158087 LOC111159436 LOC111159436 LOC111160304 LOC111160304 LOC111159768 LOC111159768 LOC111160383 LOC111160383 LOC111160657 LOC111160657 LOC111160330 LOC111160330 LOC111160728 LOC111160728 LOC111158275 LOC111158275 LOC111158286 LOC111158286 LOC111161193 LOC111161193 LOC111161374 LOC111161374 LOC111159984 LOC111159984 LOC111161133 LOC111161133 LOC111161192 LOC111161192 LOC111161785 LOC111161785 LOC111161815 LOC111161815 LOC111158897 LOC111158897 LOC111161793 LOC111161793 LOC111162066 LOC111162066 LOC111161901 LOC111161901 LOC111159748 LOC111159748 LOC111162570 LOC111162570 LOC111162236 LOC111162236 LOC111160772 LOC111160772 LOC111162471 LOC111162471 LOC111162208 LOC111162208 LOC111162302 LOC111162302
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111138962High affinity immunoglobulin epsilon receptor subunit gamma. (86 aa)
LOC111139074LOW QUALITY PROTEIN: high affinity immunoglobulin epsilon receptor subunit alpha. (294 aa)
LOC111139613Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
LOC111140316GTPase HRas isoform X1. (189 aa)
LOC111141024Serine/threonine-protein phosphatase. (309 aa)
LOC1111416201-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
LOC111142435Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa)
LOC111141782Serine palmitoyltransferase 3. (552 aa)
LOC1111414321-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC111142759Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
LOC111143470Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa)
LOC111138525Sphingosine-1-phosphate phosphatase 2. (399 aa)
LOC111143783Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
LOC111143790Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa)
LOC111143048Sphingosine 1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
LOC111143238GTPase NRas. (189 aa)
LOC111143343Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
LOC111144026Transforming protein RhoA isoform X1. (193 aa)
LOC111144322RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
LOC111144244Ceramide synthase 1. (350 aa)
LOC111144543Serine/threonine-protein phosphatase. (309 aa)
LOC111144778Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (388 aa)
LOC111144609Acid ceramidase; Belongs to the acid ceramidase family. (395 aa)
LOC111144860Mitogen-activated protein kinase. (427 aa)
LOC111144887Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (453 aa)
LOC111143159Delta-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (370 aa)
LOC111145250Sphingosine-1-phosphate lyase 1. (568 aa)
LOC111145321Neutral ceramidase. (772 aa)
LOC111145572Ceramide synthase 6 isoform X2. (392 aa)
LOC111146098Guanine nucleotide-binding protein subunit alpha-12 isoform X1. (383 aa)
LOC111146100TNF receptor-associated factor 2 isoform X1. (723 aa)
LOC111145636Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa)
LOC111145303Phosphatidylcholine:ceramide cholinephosphotransferase 1. (409 aa)
LOC111147502Mitogen-activated protein kinase kinase kinase 5 isoform X1. (1364 aa)
LOC111145476TNF receptor-associated factor 2-like. (347 aa)
LOC111147545Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC111147753Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (676 aa)
LOC111148688Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2. (323 aa)
LOC111148624Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (578 aa)
LOC111148709B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family. (392 aa)
LOC111149174Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
LOC111148513Serine palmitoyltransferase 2. (561 aa)
LOC111148765Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC111149567Cathepsin D; Belongs to the peptidase A1 family. (410 aa)
LOC111148821Kininogen-1 isoform X1. (661 aa)
LOC111149986Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
LOC1111500051-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1231 aa)
LOC111150191High affinity immunoglobulin epsilon receptor subunit beta. (243 aa)
LOC111150885Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC111150825Sphingolipid delta(4)-desaturase DES1 isoform X1. (323 aa)
LOC111151074Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
LOC111150121Phospholipase. (1074 aa)
LOC111149390High affinity immunoglobulin epsilon receptor subunit beta-like. (287 aa)
LOC111152183Mitogen-activated protein kinase. (360 aa)
LOC111152267Mitogen-activated protein kinase. (366 aa)
LOC111149956Transcription factor p65. (542 aa)
LOC111152682Ceramide synthase 3 isoform X1. (389 aa)
LOC111150668Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (487 aa)
LOC111152248Tumor necrosis factor isoform X1; Belongs to the tumor necrosis factor family. (234 aa)
LOC111153611Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa)
LOC111153496Serine palmitoyltransferase 1-like. (298 aa)
LOC111153498Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
LOC111154016Mitogen-activated protein kinase. (464 aa)
LOC111153735Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2. (663 aa)
LOC111152832Tumor necrosis factor receptor type 1-associated DEATH domain protein. (314 aa)
LOC111154409Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa)
LOC111153158Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LOC111154402Nitric oxide synthase; Produces nitric oxide (NO). (1211 aa)
LOC111154565Protein kinase C zeta type isoform X1. (646 aa)
LOC111155025Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1. (1148 aa)
LOC111155003LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC111154090Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1398 aa)
LOC111155312Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
LOC111155379Protein FAN isoform X1. (917 aa)
LOC111155859Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
LOC111154641Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
LOC111156238Multidrug resistance-associated protein 1. (1531 aa)
LOC111153624LOW QUALITY PROTEIN: sphingosine 1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (396 aa)
LOC111154217Apoptosis regulator Bcl-2. (234 aa)
LOC111157091Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta. (578 aa)
LOC111154506GRB2-associated-binding protein 2 isoform X1. (688 aa)
LOC111156936Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (550 aa)
LOC111157484Ras-related C3 botulinum toxin substrate 2. (192 aa)
LOC111157064Phosphatidylcholine:ceramide cholinephosphotransferase 2. (365 aa)
LOC111158131Guanine nucleotide-binding protein subunit alpha-13 isoform X1. (377 aa)
LOC111157625Mitogen-activated protein kinase. (364 aa)
LOC111155224Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
LOC111157957Ceramide synthase 5 isoform X1. (394 aa)
LOC1111562933-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
LOC111157628Mitogen-activated protein kinase 12 isoform X1. (486 aa)
LOC111156598Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
LOC111159912Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1. (453 aa)
LOC111158087Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
LOC111159436Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (625 aa)
LOC111160304Ras-related C3 botulinum toxin substrate 3 isoform X1. (219 aa)
LOC111159768BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (195 aa)
LOC111160383Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
LOC111160657Apoptosis regulator BAX isoform X1. (206 aa)
LOC111160330Sphingosine kinase 1 isoform X1. (486 aa)
LOC111160728Sphingosine kinase 2 isoform X1. (669 aa)
LOC111158275Tyrosine-protein kinase. (537 aa)
LOC111158286Sphingomyelin phosphodiesterase 2. (422 aa)
LOC111161193Phospholipase. (933 aa)
LOC111161374Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC111159984GTPase KRas isoform X1. (227 aa)
LOC111161133Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (379 aa)
LOC111161192Sphingosine-1-phosphate phosphatase 1 isoform X1. (445 aa)
LOC111161785Sphingosine 1-phosphate receptor 4; Belongs to the G-protein coupled receptor 1 family. (385 aa)
LOC111161815Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
LOC111158897Mitogen-activated protein kinase 9 isoform X1. (443 aa)
LOC111161793Ceramide synthase 4. (393 aa)
LOC111162066Ceramide synthase 2 isoform X1. (391 aa)
LOC111161901Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (263 aa)
LOC111159748Tumor necrosis factor receptor superfamily member 1A. (458 aa)
LOC111162570Sphingosine 1-phosphate receptor 5. (398 aa)
LOC111162236Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (372 aa)
LOC111160772Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1. (590 aa)
LOC111162471Sphingosine 1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (352 aa)
LOC111162208Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC1111623021-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1220 aa)
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
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