STRINGSTRING
LOC111138909 LOC111138909 LOC111139288 LOC111139288 LOC111139613 LOC111139613 LOC111140038 LOC111140038 LOC111140597 LOC111140597 LOC111140343 LOC111140343 LOC111140972 LOC111140972 LOC111139050 LOC111139050 LOC111140157 LOC111140157 LOC111141074 LOC111141074 LOC111141363 LOC111141363 LOC111141132 LOC111141132 LOC111139483 LOC111139483 LOC111139489 LOC111139489 LOC111141765 LOC111141765 LOC111141709 LOC111141709 LOC111141773 LOC111141773 LOC111141620 LOC111141620 LOC111141992 LOC111141992 LOC111141312 LOC111141312 LOC111142114 LOC111142114 LOC111140619 LOC111140619 LOC111141614 LOC111141614 LOC111142435 LOC111142435 LOC111142795 LOC111142795 LOC111142559 LOC111142559 LOC111142984 LOC111142984 LOC111141432 LOC111141432 LOC111143116 LOC111143116 LOC111143122 LOC111143122 LOC111142759 LOC111142759 LOC111143589 LOC111143589 LOC111141916 LOC111141916 LOC111143738 LOC111143738 LOC111144045 LOC111144045 LOC111144026 LOC111144026 LOC111144322 LOC111144322 LOC111144610 LOC111144610 LOC111144767 LOC111144767 LOC111143399 LOC111143399 LOC111144685 LOC111144685 LOC111145213 LOC111145213 LOC111145232 LOC111145232 LOC111144833 LOC111144833 LOC111144005 LOC111144005 LOC111145687 LOC111145687 LOC111145718 LOC111145718 LOC111146098 LOC111146098 LOC111146108 LOC111146108 LOC111146667 LOC111146667 LOC111147095 LOC111147095 LOC111147553 LOC111147553 LOC111147986 LOC111147986 LOC111148494 LOC111148494 LOC111150005 LOC111150005 LOC111149842 LOC111149842 LOC111150407 LOC111150407 LOC111149674 LOC111149674 LOC111150851 LOC111150851 LOC111150582 LOC111150582 LOC111150782 LOC111150782 LOC111151934 LOC111151934 LOC111151941 LOC111151941 LOC111151011 LOC111151011 LOC111152507 LOC111152507 LOC111150962 LOC111150962 LOC111150995 LOC111150995 LOC111153498 LOC111153498 LOC111153821 LOC111153821 LOC111154115 LOC111154115 LOC111151406 LOC111151406 LOC111154044 LOC111154044 LOC111153158 LOC111153158 LOC111153268 LOC111153268 LOC111154752 LOC111154752 LOC111152292 LOC111152292 LOC111154927 LOC111154927 LOC111154981 LOC111154981 LOC111154090 LOC111154090 LOC111155859 LOC111155859 LOC111155838 LOC111155838 LOC111156133 LOC111156133 LOC111153427 LOC111153427 LOC111154855 LOC111154855 LOC111154930 LOC111154930 LOC111156318 LOC111156318 LOC111153798 LOC111153798 LOC111156412 LOC111156412 LOC111156738 LOC111156738 LOC111157051 LOC111157051 LOC111156746 LOC111156746 LOC111154579 LOC111154579 LOC111157401 LOC111157401 LOC111157482 LOC111157482 LOC111154809 LOC111154809 LOC111157326 LOC111157326 LOC111157825 LOC111157825 LOC111154917 LOC111154917 LOC111154931 LOC111154931 LOC111155044 LOC111155044 LOC111156372 LOC111156372 LOC111158131 LOC111158131 LOC111158606 LOC111158606 LOC111155989 LOC111155989 LOC111156262 LOC111156262 LOC111157586 LOC111157586 LOC111157595 LOC111157595 LOC111159807 LOC111159807 LOC111159674 LOC111159674 LOC111156670 LOC111156670 LOC111158087 LOC111158087 LOC111159460 LOC111159460 LOC111160096 LOC111160096 LOC111159481 LOC111159481 LOC111157054 LOC111157054 LOC111160214 LOC111160214 LOC111160516 LOC111160516 LOC111159979 LOC111159979 LOC111160733 LOC111160733 LOC111160648 LOC111160648 LOC111158594 LOC111158594 LOC111158618 LOC111158618 LOC111160069 LOC111160069 LOC111161815 LOC111161815 LOC111161570 LOC111161570 LOC111162039 LOC111162039 LOC111161857 LOC111161857 LOC111162516 LOC111162516 LOC111162236 LOC111162236 LOC111160213 LOC111160213 LOC111160468 LOC111160468 LOC111161080 LOC111161080 LOC111162403 LOC111162403 LOC111162208 LOC111162208 LOC111162302 LOC111162302
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111138909Guanylate cyclase. (1058 aa)
LOC111139288Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
LOC111139613Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
LOC111140038Protein phosphatase 1 regulatory subunit 12C. (689 aa)
LOC111140597Calcitonin receptor-stimulating peptide 1-like. (129 aa)
LOC111140343Calcitonin receptor-stimulating peptide 2-like. (127 aa)
LOC111140972Calcium-activated potassium channel subunit beta-1. (191 aa)
LOC111139050Rho guanine nucleotide exchange factor 11 isoform X1. (1592 aa)
LOC111140157Phospholipase A2. (835 aa)
LOC111141074Calcitonin gene-related peptide type 1 receptor; Belongs to the G-protein coupled receptor 2 family. (462 aa)
LOC111141363Myosin regulatory light polypeptide 9 isoform X1. (172 aa)
LOC111141132alpha-1B adrenergic receptor. (518 aa)
LOC111139483Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa)
LOC111139489Rho guanine nucleotide exchange factor 1 isoform X1. (987 aa)
LOC111141765alpha-1D adrenergic receptor. (571 aa)
LOC111141709Myosin light chain kinase 2, skeletal/cardiac muscle. (592 aa)
LOC111141773Vasopressin-neurophysin 2-copeptin; Belongs to the vasopressin/oxytocin family. (166 aa)
LOC1111416201-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
LOC111141992Protein phosphatase 1 regulatory subunit. (1045 aa)
LOC111141312Neuroendocrine secretory protein 55. (249 aa)
LOC111142114Calcium-activated potassium channel subunit beta-4. (210 aa)
LOC111140619Phospholipase A2. (812 aa)
LOC111141614LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (1019 aa)
LOC111142435Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa)
LOC111142795LOW QUALITY PROTEIN: cytochrome P450 4A6-like; Belongs to the cytochrome P450 family. (471 aa)
LOC111142559Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
LOC111142984Cytochrome P450 4A11-like isoform X1; Belongs to the cytochrome P450 family. (510 aa)
LOC1111414321-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC111143116LOW QUALITY PROTEIN: cytochrome P450 4A6-like. (357 aa)
LOC111143122Cytochrome P450 4A11-like; Belongs to the cytochrome P450 family. (478 aa)
LOC111142759Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
LOC111143589Endothelin-2. (178 aa)
LOC111141916Endothelin-3. (196 aa)
LOC111143738Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
LOC111144045Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
LOC111144026Transforming protein RhoA isoform X1. (193 aa)
LOC111144322RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
LOC111144610Potassium channel subfamily U member 1. (1134 aa)
LOC111144767Serine/threonine-protein phosphatase. (316 aa)
LOC111143399cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
LOC111144685Calcium-activated potassium channel subunit alpha-1 isoform X2. (1263 aa)
LOC111145213cGMP-dependent protein kinase. (686 aa)
LOC111145232Group XIIB secretory phospholipase A2-like protein isoform X1. (195 aa)
LOC111144833Actin, aortic smooth muscle. (377 aa)
LOC111144005Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa)
LOC111145687Receptor activity-modifying protein 1. (126 aa)
LOC111145718C-type natriuretic peptide. (126 aa)
LOC111146098Guanine nucleotide-binding protein subunit alpha-12 isoform X1. (383 aa)
LOC111146108Guanylate cyclase. (1059 aa)
LOC111146667Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
LOC111147095LOW QUALITY PROTEIN: guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (707 aa)
LOC111147553Calcium-activated potassium channel subunit beta-3. (168 aa)
LOC111147986Actin, gamma-enteric smooth muscle. (376 aa)
LOC111148494Calmodulin-1 isoform X1; Belongs to the calmodulin family. (196 aa)
LOC1111500051-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1231 aa)
LOC111149842Calcitonin gene-related peptide 2 isoform X1. (130 aa)
LOC111150407Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1984 aa)
LOC111149674Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
LOC111150851Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
LOC111150582Serine/threonine-protein kinase A-Raf isoform X1. (628 aa)
LOC111150782Phospholipase A2. (749 aa)
LOC111151934Caldesmon. (743 aa)
LOC111151941Serine/threonine-protein kinase B-raf isoform X1. (817 aa)
LOC111151011Protein phosphatase 1 regulatory subunit. (1058 aa)
LOC111152507Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
LOC111150962Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (422 aa)
LOC111150995Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
LOC111153498Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
LOC111153821LOW QUALITY PROTEIN: guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (737 aa)
LOC111154115Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
LOC111151406Receptor activity-modifying protein 2 isoform X1. (193 aa)
LOC111154044Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
LOC111153158Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LOC111153268Calmodulin-like protein 4 isoform X1. (153 aa)
LOC111154752Natriuretic peptides A. (152 aa)
LOC111152292Calcium-activated potassium channel subunit beta-2. (235 aa)
LOC111154927Phospholipase A(2). (211 aa)
LOC111154981Myosin light chain kinase, smooth muscle isoform X1. (1974 aa)
LOC111154090Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1398 aa)
LOC111155859Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
LOC111155838Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
LOC111156133Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
LOC111153427Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1093 aa)
LOC111154855Calmodulin-like protein 6. (212 aa)
LOC111154930Phospholipase A(2). (170 aa)
LOC111156318Phospholipase A(2). (148 aa)
LOC111153798Rho guanine nucleotide exchange factor 12 isoform X1. (1524 aa)
LOC111156412alpha-1A adrenergic receptor. (466 aa)
LOC111156738Endothelin-1. (202 aa)
LOC111157051Receptor activity-modifying protein 3. (150 aa)
LOC111156746Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
LOC111154579Phospholipase A(2). (142 aa)
LOC111157401Myosin light chain kinase 3 isoform X1. (807 aa)
LOC11115748285/88 kDa calcium-independent phospholipase A2 isoform X1. (806 aa)
LOC111154809Phospholipase A(2). (137 aa)
LOC111157326Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
LOC111157825Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC111154917Phospholipase A(2). (145 aa)
LOC111154931Natriuretic peptides B. (129 aa)
LOC111155044Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
LOC111156372Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
LOC111158131Guanine nucleotide-binding protein subunit alpha-13 isoform X1. (377 aa)
LOC111158606Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
LOC111155989Myosin-11 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2001 aa)
LOC111156262Phospholipase A(2). (159 aa)
LOC111157586Myosin-9 isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)
LOC111157595Group XIIA secretory phospholipase A2. (190 aa)
LOC111159807Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
LOC111159674Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2191 aa)
LOC111156670Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (408 aa)
LOC111158087Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
LOC111159460ADM isoform X1. (188 aa)
LOC111160096Group 3 secretory phospholipase A2. (513 aa)
LOC111159481LOW QUALITY PROTEIN: protein MRVI1. (903 aa)
LOC111157054Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1138 aa)
LOC111160214Myosin light polypeptide 6 isoform X1. (160 aa)
LOC111160516Angiotensinogen; Belongs to the serpin family. (477 aa)
LOC111159979Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
LOC111160733Prostacyclin receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
LOC111160648Myosin-14 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2038 aa)
LOC111158594Calmodulin-like. (149 aa)
LOC111158618Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
LOC111160069Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
LOC111161815Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
LOC111161570Protein phosphatase 1 regulatory subunit 14A isoform X1. (147 aa)
LOC111162039Phospholipase A2. (840 aa)
LOC111161857Guanine nucleotide-binding protein subunit alpha-11. (353 aa)
LOC111162516cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC111162236Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (372 aa)
LOC111160213Myosin light chain 6B. (209 aa)
LOC111160468Phospholipase A2. (847 aa)
LOC111161080Myosin-10 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
LOC111162403Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1113 aa)
LOC111162208Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC1111623021-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1220 aa)
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
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