STRINGSTRING
LOC111138952 LOC111138952 LOC111139191 LOC111139191 LOC111140276 LOC111140276 LOC111141423 LOC111141423 LOC111141099 LOC111141099 LOC111141617 LOC111141617 LOC111142363 LOC111142363 LOC111142438 LOC111142438 LOC111142881 LOC111142881 LOC111142990 LOC111142990 LOC111143174 LOC111143174 LOC111141582 LOC111141582 LOC111143244 LOC111143244 LOC111142759 LOC111142759 LOC111142126 LOC111142126 LOC111142395 LOC111142395 LOC111144797 LOC111144797 LOC111144860 LOC111144860 LOC111144102 LOC111144102 LOC111144921 LOC111144921 LOC111144397 LOC111144397 LOC111144592 LOC111144592 LOC111143876 LOC111143876 LOC111146039 LOC111146039 LOC111146053 LOC111146053 LOC111146071 LOC111146071 LOC111147275 LOC111147275 LOC111147365 LOC111147365 LOC111147686 LOC111147686 LOC111147500 LOC111147500 LOC111147725 LOC111147725 LOC111148007 LOC111148007 LOC111150492 LOC111150492 LOC111148518 LOC111148518 LOC111148602 LOC111148602 LOC111150748 LOC111150748 LOC111151093 LOC111151093 LOC111151020 LOC111151020 LOC111151320 LOC111151320 LOC111151211 LOC111151211 LOC111151253 LOC111151253 LOC111152169 LOC111152169 LOC111152191 LOC111152191 LOC111152151 LOC111152151 LOC111152183 LOC111152183 LOC111152200 LOC111152200 LOC111152259 LOC111152259 LOC111152168 LOC111152168 LOC111152267 LOC111152267 LOC111149956 LOC111149956 LOC111152383 LOC111152383 LOC111152476 LOC111152476 LOC111153179 LOC111153179 LOC111152158 LOC111152158 LOC111152175 LOC111152175 LOC111152178 LOC111152178 LOC111153611 LOC111153611 LOC111152451 LOC111152451 LOC111153517 LOC111153517 LOC111152499 LOC111152499 LOC111151241 LOC111151241 LOC111152752 LOC111152752 LOC111154016 LOC111154016 LOC111153842 LOC111153842 LOC111153962 LOC111153962 LOC111154209 LOC111154209 LOC111151590 LOC111151590 LOC111154144 LOC111154144 LOC111154566 LOC111154566 LOC111152195 LOC111152195 LOC111152356 LOC111152356 LOC111152358 LOC111152358 LOC111152452 LOC111152452 LOC111153823 LOC111153823 LOC111155682 LOC111155682 LOC111153212 LOC111153212 LOC111155922 LOC111155922 LOC111154869 LOC111154869 LOC111154883 LOC111154883 LOC111156757 LOC111156757 LOC111155817 LOC111155817 LOC111155931 LOC111155931 LOC111156948 LOC111156948 LOC111157589 LOC111157589 LOC111157625 LOC111157625 LOC111158621 LOC111158621 LOC111158999 LOC111158999 LOC111157559 LOC111157559 LOC111157628 LOC111157628 LOC111159932 LOC111159932 LOC111159821 LOC111159821 LOC111158456 LOC111158456 LOC111160115 LOC111160115 LOC111158640 LOC111158640 LOC111160242 LOC111160242 LOC111161594 LOC111161594 LOC111158618 LOC111158618 LOC111158897 LOC111158897 LOC111161964 LOC111161964 LOC111159390 LOC111159390 LOC111162219 LOC111162219 LOC111162191 LOC111162191 LOC111162236 LOC111162236 LOC111161420 LOC111161420 LOC111162412 LOC111162412 LOC111162173 LOC111162173 LOC111161041 LOC111161041 LOC111162402 LOC111162402
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111138952Interleukin-6 receptor subunit alpha isoform X4. (468 aa)
LOC111139191NF-kappa-B essential modulator. (412 aa)
LOC111140276NF-kappa-B inhibitor alpha isoform X1. (358 aa)
LOC1111414231-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
LOC111141099Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (132 aa)
LOC111141617Interferon regulatory factor 4-like. (382 aa)
LOC111142363Interleukin-22. (178 aa)
LOC111142438Mothers against decapentaplegic homolog. (552 aa)
LOC111142881Tyrosine-protein kinase. (1153 aa)
LOC111142990Tyrosine-protein kinase. (509 aa)
LOC111143174Transcription factor AP-1; Belongs to the bZIP family. (334 aa)
LOC111141582LOW QUALITY PROTEIN: nuclear factor of activated T-cells, cytoplasmic 2. (912 aa)
LOC111143244Interleukin-23 receptor. (631 aa)
LOC111142759Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
LOC111142126Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
LOC111142395Mothers against decapentaplegic homolog. (467 aa)
LOC111144797Serine/threonine-protein phosphatase. (534 aa)
LOC111144860Mitogen-activated protein kinase. (427 aa)
LOC111144102Interleukin-12 receptor subunit beta-1 isoform X1. (751 aa)
LOC111144921Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
LOC111144397Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
LOC111144592Signal transducer and activator of transcription. (750 aa)
LOC111143876Tyrosine-protein kinase. (1107 aa)
LOC111146039Retinoic acid receptor RXR-alpha. (439 aa)
LOC111146053Calcineurin subunit B type 2. (170 aa)
LOC111146071Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
LOC111147275Aryl hydrocarbon receptor. (848 aa)
LOC111147365Interleukin-6 isoform X2. (212 aa)
LOC111147686Interferon gamma receptor 1. (474 aa)
LOC111147500Heat shock protein HSP 90-beta. (724 aa)
LOC111147725NF-kappa-B inhibitor epsilon. (362 aa)
LOC111148007Calcineurin subunit B type 1. (170 aa)
LOC111150492Forkhead box protein P3 isoform X1. (432 aa)
LOC111148518Heat shock protein HSP 90-alpha. (733 aa)
LOC111148602Proto-oncogene c-Fos. (380 aa)
LOC111150748T-cell surface glycoprotein CD3 zeta chain isoform X1. (185 aa)
LOC111151093Interleukin-1 receptor accessory protein isoform X1. (685 aa)
LOC111151020Retinoic acid receptor RXR-gamma isoform X1. (463 aa)
LOC111151320Retinoic acid receptor alpha isoform X1. (472 aa)
LOC111151211Signal transducer and activator of transcription. (794 aa)
LOC111151253Signal transducer and activator of transcription. (787 aa)
LOC111152169HLA class II histocompatibility antigen, DM alpha chain; Belongs to the MHC class II family. (261 aa)
LOC111152191HLA class II histocompatibility antigen, DO beta chain isoform X1. (296 aa)
LOC111152151SLA class II histocompatibility antigen, DQ haplotype C beta chain-like. (270 aa)
LOC111152183Mitogen-activated protein kinase. (360 aa)
LOC111152200HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (254 aa)
LOC111152259DLA class II histocompatibility antigen, DR-1 beta chain isoform X1. (291 aa)
LOC111152168HLA class II histocompatibility antigen, DM beta chain. (263 aa)
LOC111152267Mitogen-activated protein kinase. (366 aa)
LOC111149956Transcription factor p65. (542 aa)
LOC111152383HLA class II histocompatibility antigen, DO alpha chain; Belongs to the MHC class II family. (250 aa)
LOC111152476interleukin-17A. (153 aa)
LOC111153179Mothers against decapentaplegic homolog. (425 aa)
LOC111152158SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like isoform X1; Belongs to the MHC class II family. (294 aa)
LOC111152175SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like isoform X1; Belongs to the MHC class II family. (252 aa)
LOC111152178LOW QUALITY PROTEIN: DLA class II histocompatibility antigen, DR-1 beta chain-like. (271 aa)
LOC111153611Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa)
LOC111152451LOW QUALITY PROTEIN: RLA class II histocompatibility antigen, DP alpha-1 chain; Belongs to the MHC class II family. (265 aa)
LOC111153517Tyrosine-protein kinase. (974 aa)
LOC111152499interleukin-17F. (158 aa)
LOC111151241Signal transducer and activator of transcription. (802 aa)
LOC111152752Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1107 aa)
LOC111154016Mitogen-activated protein kinase. (464 aa)
LOC111153842T-cell surface glycoprotein CD3 gamma chain. (180 aa)
LOC111153962T-cell surface glycoprotein CD3 epsilon chain isoform X1. (192 aa)
LOC111154209Nuclear factor of activated T-cells, cytoplasmic 1 isoform X1. (931 aa)
LOC111151590T-box transcription factor TBX21. (535 aa)
LOC111154144Serine/threonine-protein phosphatase. (534 aa)
LOC111154566Serine/threonine-protein phosphatase. (521 aa)
LOC111152195Retinoic acid receptor RXR-beta isoform X1. (589 aa)
LOC111152356HLA class II histocompatibility antigen, DQ beta 1 chain isoform X1. (279 aa)
LOC111152358LOW QUALITY PROTEIN: HLA class II histocompatibility antigen, DR alpha chain-like; Belongs to the MHC class II family. (241 aa)
LOC111152452HLA class II histocompatibility antigen, DP beta 1 chain-like. (255 aa)
LOC111153823T-cell surface glycoprotein CD3 delta chain isoform X1. (169 aa)
LOC111155682Interferon gamma receptor 2 isoform X2. (353 aa)
LOC111153212Nuclear receptor ROR-alpha isoform X1. (523 aa)
LOC111155922Tyrosine-protein kinase. (616 aa)
LOC111154869Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
LOC111154883Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
LOC111156757Interferon regulatory factor 4 isoform X1. (451 aa)
LOC111155817Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
LOC111155931Interleukin-1 receptor type 1. (573 aa)
LOC111156948Interleukin-6 receptor subunit beta. (918 aa)
LOC111157589Interleukin; Belongs to the IL-15/IL-21 family. (153 aa)
LOC111157625Mitogen-activated protein kinase. (364 aa)
LOC111158621Interleukin-2 receptor subunit alpha isoform X1. (275 aa)
LOC111158999TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
LOC111157559Interleukin-2 receptor subunit beta isoform X1. (560 aa)
LOC111157628Mitogen-activated protein kinase 12 isoform X1. (486 aa)
LOC111159932interleukin-17D. (202 aa)
LOC111159821T-cell surface glycoprotein CD4 isoform X1. (463 aa)
LOC111158456Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (270 aa)
LOC111160115Signal transducer and activator of transcription. (844 aa)
LOC111158640Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
LOC111160242Interleukin-23 subunit alpha. (193 aa)
LOC111161594NF-kappa-B inhibitor beta. (354 aa)
LOC111158618Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
LOC111158897Mitogen-activated protein kinase 9 isoform X1. (443 aa)
LOC111161964Nuclear receptor ROR-gamma. (518 aa)
LOC111159390Hypoxia-inducible factor 1-alpha isoform X1. (823 aa)
LOC111162219Linker for activation of T-cells family member 1 isoform X1. (260 aa)
LOC111162191Interleukin-4 receptor subunit alpha isoform X1. (806 aa)
LOC111162236Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (372 aa)
LOC111161420Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
LOC111162412Interleukin-27 receptor subunit alpha. (749 aa)
LOC111162173Interleukin-21 receptor isoform X1. (545 aa)
LOC111161041Cytokine receptor common subunit gamma. (374 aa)
LOC111162402Tyrosine-protein kinase. (1198 aa)
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
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