STRINGSTRING
LOC111139030 LOC111139030 LOC111139263 LOC111139263 LOC111139613 LOC111139613 LOC111140421 LOC111140421 LOC111140968 LOC111140968 LOC111140840 LOC111140840 LOC111141620 LOC111141620 LOC111141312 LOC111141312 LOC111142166 LOC111142166 LOC111142372 LOC111142372 LOC111141614 LOC111141614 LOC111142967 LOC111142967 LOC111141432 LOC111141432 LOC111143000 LOC111143000 LOC111143157 LOC111143157 LOC111142759 LOC111142759 LOC111143738 LOC111143738 LOC111143783 LOC111143783 LOC111143343 LOC111143343 LOC111144644 LOC111144644 LOC111144745 LOC111144745 LOC111143399 LOC111143399 LOC111145213 LOC111145213 LOC111145586 LOC111145586 LOC111145432 LOC111145432 LOC111144005 LOC111144005 LOC111145775 LOC111145775 LOC111145278 LOC111145278 LOC111145828 LOC111145828 LOC111145480 LOC111145480 LOC111146667 LOC111146667 LOC111147281 LOC111147281 LOC111147095 LOC111147095 LOC111147511 LOC111147511 LOC111147575 LOC111147575 LOC111147333 LOC111147333 LOC111148494 LOC111148494 LOC111148588 LOC111148588 LOC111149130 LOC111149130 LOC111147323 LOC111147323 LOC111150005 LOC111150005 LOC111148567 LOC111148567 LOC111148602 LOC111148602 LOC111151138 LOC111151138 LOC111149566 LOC111149566 LOC111151818 LOC111151818 LOC111151233 LOC111151233 LOC111152507 LOC111152507 LOC111150861 LOC111150861 LOC111153760 LOC111153760 LOC111153498 LOC111153498 LOC111153821 LOC111153821 LOC111154115 LOC111154115 LOC111154044 LOC111154044 LOC111153268 LOC111153268 LOC111153485 LOC111153485 LOC111154601 LOC111154601 LOC111154647 LOC111154647 LOC111155312 LOC111155312 LOC111154372 LOC111154372 LOC111155838 LOC111155838 LOC111156133 LOC111156133 LOC111153427 LOC111153427 LOC111154855 LOC111154855 LOC111153762 LOC111153762 LOC111156411 LOC111156411 LOC111156207 LOC111156207 LOC111153936 LOC111153936 LOC111155756 LOC111155756 LOC111157525 LOC111157525 LOC111157250 LOC111157250 LOC111157326 LOC111157326 LOC111157825 LOC111157825 LOC111155044 LOC111155044 LOC111158606 LOC111158606 LOC111156013 LOC111156013 LOC111156070 LOC111156070 LOC111159558 LOC111159558 LOC111159674 LOC111159674 LOC111158087 LOC111158087 LOC111156985 LOC111156985 LOC111157054 LOC111157054 LOC111157367 LOC111157367 LOC111161174 LOC111161174 LOC111159618 LOC111159618 LOC111159773 LOC111159773 LOC111160835 LOC111160835 LOC111158594 LOC111158594 LOC111161718 LOC111161718 LOC111160373 LOC111160373 LOC111160688 LOC111160688 LOC111162516 LOC111162516 LOC111162236 LOC111162236 LOC111161376 LOC111161376 LOC111160502 LOC111160502 LOC111162403 LOC111162403 LOC111162432 LOC111162432 LOC111162208 LOC111162208 LOC111162302 LOC111162302
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111139030G protein-activated inward rectifier potassium channel 3. (392 aa)
LOC111139263Dexamethasone-induced Ras-related protein 1. (279 aa)
LOC111139613Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
LOC111140421Guanine nucleotide-binding protein subunit beta-5. (353 aa)
LOC111140968Glutamate receptor 1 isoform X1. (906 aa)
LOC111140840Calcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (489 aa)
LOC1111416201-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
LOC111141312Neuroendocrine secretory protein 55. (249 aa)
LOC111142166Glutamate receptor ionotropic, NMDA 2B. (1484 aa)
LOC111142372Pituitary adenylate cyclase-activating polypeptide. (176 aa)
LOC111141614LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (1019 aa)
LOC111142967Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC1111414321-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC111143000Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC111143157G protein-activated inward rectifier potassium channel 1. (501 aa)
LOC111142759Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
LOC111143738Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
LOC111143783Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
LOC111143343Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
LOC111144644Melatonin receptor type 1A; Belongs to the G-protein coupled receptor 1 family. (364 aa)
LOC111144745LOW QUALITY PROTEIN: ryanodine receptor 2. (5099 aa)
LOC111143399cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
LOC111145213cGMP-dependent protein kinase. (686 aa)
LOC111145586Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X1. (340 aa)
LOC111145432Calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1. (577 aa)
LOC111144005Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa)
LOC111145775Glutamate receptor ionotropic, NMDA 1 isoform X1. (943 aa)
LOC111145278LOW QUALITY PROTEIN: period circadian protein homolog 2. (1270 aa)
LOC111145828Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC111145480Glutamate receptor ionotropic, NMDA 1-like. (491 aa)
LOC111146667Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
LOC111147281Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
LOC111147095LOW QUALITY PROTEIN: guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (707 aa)
LOC111147511Adenylate cyclase type 10-like isoform X1. (1595 aa)
LOC111147575Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
LOC111147333Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
LOC111148494Calmodulin-1 isoform X1; Belongs to the calmodulin family. (196 aa)
LOC111148588Guanine nucleotide-binding protein subunit beta-4. (340 aa)
LOC111149130cGMP-dependent protein kinase. (762 aa)
LOC111147323Pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (497 aa)
LOC1111500051-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1231 aa)
LOC111148567Ribosomal protein S6 kinase. (798 aa)
LOC111148602Proto-oncogene c-Fos. (380 aa)
LOC111151138Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform X1. (752 aa)
LOC111149566Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC111151818Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
LOC111151233Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2369 aa)
LOC111152507Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
LOC111150861Adenylate cyclase type 10. (1610 aa)
LOC111153760Glutamate receptor 4 isoform X1. (902 aa)
LOC111153498Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
LOC111153821LOW QUALITY PROTEIN: guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (737 aa)
LOC111154115Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
LOC111154044Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
LOC111153268Calmodulin-like protein 4 isoform X1. (153 aa)
LOC111153485Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X3. (544 aa)
LOC111154601Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
LOC111154647Period circadian protein homolog 3 isoform X1. (1139 aa)
LOC111155312Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
LOC111154372Melatonin receptor type 1B; Belongs to the G-protein coupled receptor 1 family. (411 aa)
LOC111155838Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
LOC111156133Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
LOC111153427Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1093 aa)
LOC111154855Calmodulin-like protein 6. (212 aa)
LOC111153762Glutamate receptor 2 isoform X1. (940 aa)
LOC111156411Nitric oxide synthase; Produces nitric oxide (NO). (1433 aa)
LOC111156207Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
LOC111153936G protein-activated inward rectifier potassium channel 4. (429 aa)
LOC111155756G protein-activated inward rectifier potassium channel 2. (423 aa)
LOC111157525Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2187 aa)
LOC111157250Glutamate receptor 3. (894 aa)
LOC111157326Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
LOC111157825Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC111155044Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
LOC111158606Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
LOC111156013Voltage-dependent T-type calcium channel subunit alpha-1H. (2342 aa)
LOC111156070Glutamate receptor ionotropic, NMDA 2A. (1464 aa)
LOC111159558Ryanodine receptor 3. (4849 aa)
LOC111159674Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2191 aa)
LOC111158087Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
LOC111156985Calcium/calmodulin-dependent protein kinase type II subunit beta. (543 aa)
LOC111157054Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1138 aa)
LOC111157367Guanine nucleotide-binding protein G(O) subunit alpha. (354 aa)
LOC111161174Period circadian protein homolog 1. (1287 aa)
LOC111159618Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (96 aa)
LOC111159773Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
LOC111160835Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC111158594Calmodulin-like. (149 aa)
LOC111161718Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC111160373Glutamate receptor ionotropic, NMDA 2C isoform X2. (1227 aa)
LOC111160688Glutamate receptor ionotropic, NMDA 2D. (1333 aa)
LOC111162516cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC111162236Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (372 aa)
LOC111161376LOW QUALITY PROTEIN: ryanodine receptor 1. (5028 aa)
LOC111160502Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC111162403Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1113 aa)
LOC111162432Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC111162208Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC1111623021-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1220 aa)
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
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