86 items (Enhydra lutris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111138822	Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
	LOC111138823	Sodium/potassium-transporting ATPase subunit alpha. (1031 aa)
	LOC111138935	Small conductance calcium-activated potassium channel protein 3 isoform X1. (724 aa)
	LOC111139613	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
	LOC111139490	Sodium/potassium-transporting ATPase subunit alpha. (1014 aa)
	LOC111139532	Intermediate conductance calcium-activated potassium channel protein 4. (526 aa)
	LOC111140972	Calcium-activated potassium channel subunit beta-1. (191 aa)
	LOC111140840	Calcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (489 aa)
	LOC111138943	Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (384 aa)
	LOC111141620	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
	LOC111141312	Neuroendocrine secretory protein 55. (249 aa)
	LOC111142114	Calcium-activated potassium channel subunit beta-4. (210 aa)
	LOC111142372	Pituitary adenylate cyclase-activating polypeptide. (176 aa)
	LOC111141614	LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (1019 aa)
	LOC111141432	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
	LOC111143264	Sodium/potassium-transporting ATPase subunit alpha. (1051 aa)
	LOC111143335	Solute carrier family 2, facilitated glucose transporter member 1 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (498 aa)
	LOC111143738	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
	LOC111143801	Ras-related protein Rab-3A. (220 aa)
	LOC111144202	LOW QUALITY PROTEIN: small conductance calcium-activated potassium channel protein 1. (548 aa)
	LOC111144610	Potassium channel subfamily U member 1. (1134 aa)
	LOC111142901	Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
	LOC111144139	Glucagon isoform X1. (180 aa)
	LOC111144745	LOW QUALITY PROTEIN: ryanodine receptor 2. (5099 aa)
	LOC111143399	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
	LOC111144973	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (626 aa)
	LOC111144685	Calcium-activated potassium channel subunit alpha-1 isoform X2. (1263 aa)
	LOC111145432	Calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1. (577 aa)
	LOC111145554	syntaxin-1A isoform X1; Belongs to the syntaxin family. (331 aa)
	LOC111146280	Cyclic AMP-responsive element-binding protein 3. (353 aa)
	LOC111146667	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
	LOC111146851	Regulating synaptic membrane exocytosis protein 2 isoform X1. (1766 aa)
	LOC111147321	Cyclic AMP-responsive element-binding protein 5. (501 aa)
	LOC111147553	Calcium-activated potassium channel subunit beta-3. (168 aa)
	LOC111147575	Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
	LOC111147323	Pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (497 aa)
	LOC111147798	Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
	LOC111150005	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1231 aa)
	LOC111149244	Cholecystokinin receptor type A; Belongs to the G-protein coupled receptor 1 family. (428 aa)
	LOC111150279	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (109 aa)
	LOC111150073	ATP-sensitive inward rectifier potassium channel 11. (390 aa)
	LOC111150407	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1984 aa)
	LOC111150877	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
	LOC111150050	Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
	LOC111150341	Solute carrier family 2, facilitated glucose transporter member 2 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
	LOC111151973	Cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1. (520 aa)
	LOC111149755	ATP-binding cassette sub-family C member 8 isoform X1. (1581 aa)
	LOC111152174	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
	LOC111152366	Cyclic AMP-dependent transcription factor ATF-6 beta isoform X1. (718 aa)
	LOC111152507	Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
	LOC111150995	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
	LOC111153498	Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
	LOC111151477	Gastric inhibitory polypeptide. (144 aa)
	LOC111154044	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
	LOC111153485	Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X3. (544 aa)
	LOC111152292	Calcium-activated potassium channel subunit beta-2. (235 aa)
	LOC111153819	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
	LOC111156133	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
	LOC111153427	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1093 aa)
	LOC111157201	Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family. (335 aa)
	LOC111157017	Phosphotransferase. (306 aa)
	LOC111157326	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
	LOC111157825	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
	LOC111155044	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
	LOC111155313	LOW QUALITY PROTEIN: protein piccolo. (5116 aa)
	LOC111158917	Rap guanine nucleotide exchange factor 4 isoform X1. (1011 aa)
	LOC111157285	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (366 aa)
	LOC111159120	Cholecystokinin. (115 aa)
	LOC111159674	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2191 aa)
	LOC111158087	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
	LOC111156985	Calcium/calmodulin-dependent protein kinase type II subunit beta. (543 aa)
	LOC111157022	Phosphotransferase. (465 aa)
	LOC111157054	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1138 aa)
	LOC111158579	Pancreas/duodenum homeobox protein 1. (281 aa)
	LOC111157635	Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
	LOC111161212	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
	LOC111158908	Small conductance calcium-activated potassium channel protein 2. (840 aa)
	LOC111161857	Guanine nucleotide-binding protein subunit alpha-11. (353 aa)
	LOC111162516	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
	LOC111161127	Vesicle-associated membrane protein 2. (116 aa)
	LOC111161614	Free fatty acid receptor 1. (299 aa)
	LOC111160558	Transient receptor potential cation channel subfamily M member 4 isoform X1. (1207 aa)
	LOC111161856	Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1. (481 aa)
	LOC111162403	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1113 aa)
	LOC111162208	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
	LOC111162302	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1220 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111138822	LOC111138823	A0A2Y9ICK9	A0A2Y9ICS7	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
LOC111138822	LOC111139490	A0A2Y9ICK9	A0A2Y9IGL5	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.900
LOC111138822	LOC111143264	A0A2Y9ICK9	A0A2Y9IVB9	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.900
LOC111138822	LOC111143399	A0A2Y9ICK9	A0A2Y9J431	Sodium/potassium-transporting ATPase subunit alpha.	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	0.909
LOC111138822	LOC111150877	A0A2Y9ICK9	A0A2Y9JTE2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.982
LOC111138822	LOC111152174	A0A2Y9ICK9	A0A2Y9JZE6	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.968
LOC111138822	LOC111153819	A0A2Y9ICK9	A0A2Y9KB13	Sodium/potassium-transporting ATPase subunit alpha.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.972
LOC111138822	LOC111157285	A0A2Y9ICK9	A0A2Y9KSQ4	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.963
LOC111138822	LOC111161212	A0A2Y9ICK9	A0A2Y9L2N2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.970
LOC111138822	LOC111162516	A0A2Y9ICK9	A0A2Y9L9E0	Sodium/potassium-transporting ATPase subunit alpha.	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.	0.909
LOC111138823	LOC111138822	A0A2Y9ICS7	A0A2Y9ICK9	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
LOC111138823	LOC111139490	A0A2Y9ICS7	A0A2Y9IGL5	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
LOC111138823	LOC111143264	A0A2Y9ICS7	A0A2Y9IVB9	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
LOC111138823	LOC111143399	A0A2Y9ICS7	A0A2Y9J431	Sodium/potassium-transporting ATPase subunit alpha.	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	0.909
LOC111138823	LOC111150877	A0A2Y9ICS7	A0A2Y9JTE2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.981
LOC111138823	LOC111152174	A0A2Y9ICS7	A0A2Y9JZE6	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.967
LOC111138823	LOC111153819	A0A2Y9ICS7	A0A2Y9KB13	Sodium/potassium-transporting ATPase subunit alpha.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.972
LOC111138823	LOC111157285	A0A2Y9ICS7	A0A2Y9KSQ4	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.963
LOC111138823	LOC111161212	A0A2Y9ICS7	A0A2Y9L2N2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.970
LOC111138823	LOC111162516	A0A2Y9ICS7	A0A2Y9L9E0	Sodium/potassium-transporting ATPase subunit alpha.	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.	0.909