75 items (Enhydra lutris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111138822	Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
	LOC111138823	Sodium/potassium-transporting ATPase subunit alpha. (1031 aa)
	LOC111139613	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
	LOC111139490	Sodium/potassium-transporting ATPase subunit alpha. (1014 aa)
	LOC111140869	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (235 aa)
	LOC111138943	Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (384 aa)
	LOC111141620	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
	LOC111141989	Low-density lipoprotein receptor-related protein 2. (4705 aa)
	LOC111141312	Neuroendocrine secretory protein 55. (249 aa)
	LOC111142066	Endoplasmin isoform X1. (803 aa)
	LOC111141614	LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (1019 aa)
	LOC111143079	Transcription termination factor 2. (1156 aa)
	LOC111141432	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
	LOC111143264	Sodium/potassium-transporting ATPase subunit alpha. (1051 aa)
	LOC111143439	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (263 aa)
	LOC111143605	Thyrotropin subunit beta. (138 aa)
	LOC111144253	Sodium/iodide cotransporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (642 aa)
	LOC111142535	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (147 aa)
	LOC111142901	Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
	LOC111143399	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
	LOC111144593	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (519 aa)
	LOC111143890	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (203 aa)
	LOC111144005	Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa)
	LOC111146558	Thyroglobulin. (2763 aa)
	LOC111146280	Cyclic AMP-responsive element-binding protein 3. (353 aa)
	LOC111145745	Transcription termination factor 1 isoform X2. (766 aa)
	LOC111146667	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
	LOC111147321	Cyclic AMP-responsive element-binding protein 5. (501 aa)
	LOC111147575	Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
	LOC111146005	78 kDa glucose-regulated protein isoform X1; Belongs to the heat shock protein 70 family. (654 aa)
	LOC111148625	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
	LOC111148905	Serum albumin. (608 aa)
	LOC111150005	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1231 aa)
	LOC111150877	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
	LOC111150050	Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
	LOC111151973	Cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1. (520 aa)
	LOC111152174	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
	LOC111152366	Cyclic AMP-dependent transcription factor ATF-6 beta isoform X1. (718 aa)
	LOC111152507	Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
	LOC111153498	Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
	LOC111154044	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
	LOC111154148	Thyroid peroxidase. (1524 aa)
	LOC111154460	Protein disulfide-isomerase A4. (645 aa)
	LOC111153819	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
	LOC111155329	Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (780 aa)
	LOC111156133	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
	LOC111153427	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1093 aa)
	LOC111156930	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
	LOC111157326	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
	LOC111157825	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
	LOC111155044	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
	LOC111158122	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (190 aa)
	LOC111158799	Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
	LOC111157285	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (366 aa)
	LOC111158087	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
	LOC111157054	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1138 aa)
	LOC111158488	Paired box protein Pax-8 isoform X1. (499 aa)
	LOC111159979	Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
	LOC111158731	Iodotyrosine deiodinase 1 isoform X1. (289 aa)
	LOC111158868	Calnexin. (593 aa)
	LOC111157635	Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
	LOC111161087	Asialoglycoprotein receptor 2. (296 aa)
	LOC111161212	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
	LOC111159740	Dual oxidase 2. (1024 aa)
	LOC111161170	Asialoglycoprotein receptor 1. (284 aa)
	LOC111161306	Thyroxine-binding globulin isoform X1; Belongs to the serpin family. (422 aa)
	LOC111161962	Dual oxidase 1. (1551 aa)
	LOC111161977	Dual oxidase maturation factor 2. (320 aa)
	LOC111162516	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
	LOC111162615	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (218 aa)
	LOC111162616	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
	LOC111161856	Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1. (481 aa)
	LOC111162403	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1113 aa)
	LOC111162208	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
	LOC111162302	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1220 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111138822	LOC111138823	A0A2Y9ICK9	A0A2Y9ICS7	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
LOC111138822	LOC111139490	A0A2Y9ICK9	A0A2Y9IGL5	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.900
LOC111138822	LOC111143264	A0A2Y9ICK9	A0A2Y9IVB9	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.900
LOC111138822	LOC111143399	A0A2Y9ICK9	A0A2Y9J431	Sodium/potassium-transporting ATPase subunit alpha.	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	0.909
LOC111138822	LOC111150877	A0A2Y9ICK9	A0A2Y9JTE2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.982
LOC111138822	LOC111152174	A0A2Y9ICK9	A0A2Y9JZE6	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.968
LOC111138822	LOC111153819	A0A2Y9ICK9	A0A2Y9KB13	Sodium/potassium-transporting ATPase subunit alpha.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.972
LOC111138822	LOC111157285	A0A2Y9ICK9	A0A2Y9KSQ4	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.963
LOC111138822	LOC111161212	A0A2Y9ICK9	A0A2Y9L2N2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.970
LOC111138822	LOC111162516	A0A2Y9ICK9	A0A2Y9L9E0	Sodium/potassium-transporting ATPase subunit alpha.	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.	0.909
LOC111138823	LOC111138822	A0A2Y9ICS7	A0A2Y9ICK9	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
LOC111138823	LOC111139490	A0A2Y9ICS7	A0A2Y9IGL5	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
LOC111138823	LOC111143264	A0A2Y9ICS7	A0A2Y9IVB9	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
LOC111138823	LOC111143399	A0A2Y9ICS7	A0A2Y9J431	Sodium/potassium-transporting ATPase subunit alpha.	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	0.909
LOC111138823	LOC111150877	A0A2Y9ICS7	A0A2Y9JTE2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.981
LOC111138823	LOC111152174	A0A2Y9ICS7	A0A2Y9JZE6	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.967
LOC111138823	LOC111153819	A0A2Y9ICS7	A0A2Y9KB13	Sodium/potassium-transporting ATPase subunit alpha.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.972
LOC111138823	LOC111157285	A0A2Y9ICS7	A0A2Y9KSQ4	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.963
LOC111138823	LOC111161212	A0A2Y9ICS7	A0A2Y9L2N2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.970
LOC111138823	LOC111162516	A0A2Y9ICS7	A0A2Y9L9E0	Sodium/potassium-transporting ATPase subunit alpha.	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.	0.909