STRINGSTRING
LOC111138822 LOC111138822 LOC111138823 LOC111138823 LOC111138909 LOC111138909 LOC111139156 LOC111139156 LOC111139613 LOC111139613 LOC111139490 LOC111139490 LOC111140840 LOC111140840 LOC111138943 LOC111138943 LOC111141620 LOC111141620 LOC111141312 LOC111141312 LOC111141614 LOC111141614 LOC111142750 LOC111142750 LOC111142249 LOC111142249 LOC111141432 LOC111141432 LOC111143264 LOC111143264 LOC111143738 LOC111143738 LOC111144498 LOC111144498 LOC111142901 LOC111142901 LOC111143877 LOC111143877 LOC111144054 LOC111144054 LOC111143399 LOC111143399 LOC111143436 LOC111143436 LOC111145635 LOC111145635 LOC111145432 LOC111145432 LOC111144005 LOC111144005 LOC111146280 LOC111146280 LOC111146667 LOC111146667 LOC111147321 LOC111147321 LOC111147575 LOC111147575 LOC111146845 LOC111146845 LOC111148494 LOC111148494 LOC111150005 LOC111150005 LOC111148267 LOC111148267 LOC111150407 LOC111150407 LOC111150851 LOC111150851 LOC111150877 LOC111150877 LOC111150050 LOC111150050 LOC111151183 LOC111151183 LOC111151973 LOC111151973 LOC111149706 LOC111149706 LOC111151233 LOC111151233 LOC111152239 LOC111152239 LOC111152174 LOC111152174 LOC111152366 LOC111152366 LOC111152507 LOC111152507 LOC111153362 LOC111153362 LOC111150995 LOC111150995 LOC111153498 LOC111153498 LOC111154044 LOC111154044 LOC111154200 LOC111154200 LOC111154189 LOC111154189 LOC111153268 LOC111153268 LOC111153485 LOC111153485 LOC111154752 LOC111154752 LOC111155859 LOC111155859 LOC111156133 LOC111156133 LOC111153427 LOC111153427 LOC111154855 LOC111154855 LOC111153936 LOC111153936 LOC111157525 LOC111157525 LOC111157326 LOC111157326 LOC111157825 LOC111157825 LOC111157882 LOC111157882 LOC111155044 LOC111155044 LOC111156453 LOC111156453 LOC111155531 LOC111155531 LOC111158360 LOC111158360 LOC111158606 LOC111158606 LOC111157285 LOC111157285 LOC111156013 LOC111156013 LOC111156379 LOC111156379 LOC111157964 LOC111157964 LOC111159674 LOC111159674 LOC111158087 LOC111158087 LOC111159411 LOC111159411 LOC111156985 LOC111156985 LOC111157054 LOC111157054 LOC111160516 LOC111160516 LOC111159979 LOC111159979 LOC111157635 LOC111157635 LOC111160605 LOC111160605 LOC111161212 LOC111161212 LOC111158594 LOC111158594 LOC111161440 LOC111161440 LOC111161857 LOC111161857 LOC111162368 LOC111162368 LOC111162516 LOC111162516 LOC111162438 LOC111162438 LOC111161610 LOC111161610 LOC111161856 LOC111161856 LOC111162403 LOC111162403 LOC111161566 LOC111161566 LOC111162208 LOC111162208 LOC111162302 LOC111162302
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111138822Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
LOC111138823Sodium/potassium-transporting ATPase subunit alpha. (1031 aa)
LOC111138909Guanylate cyclase. (1058 aa)
LOC111139156Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1227 aa)
LOC111139613Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
LOC111139490Sodium/potassium-transporting ATPase subunit alpha. (1014 aa)
LOC111140840Calcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (489 aa)
LOC111138943Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (384 aa)
LOC1111416201-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
LOC111141312Neuroendocrine secretory protein 55. (249 aa)
LOC111141614LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (1019 aa)
LOC111142750Adrenocorticotropic hormone receptor. (297 aa)
LOC111142249Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
LOC1111414321-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC111143264Sodium/potassium-transporting ATPase subunit alpha. (1051 aa)
LOC111143738Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
LOC111144498Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
LOC111142901Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
LOC111143877Calcium/calmodulin-dependent protein kinase type 1 isoform X2; Belongs to the protein kinase superfamily. (409 aa)
LOC111144054Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
LOC111143399cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
LOC1111434363 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; Belongs to the 3-beta-HSD family. (373 aa)
LOC111145635Sn1-specific diacylglycerol lipase beta. (671 aa)
LOC111145432Calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1. (577 aa)
LOC111144005Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa)
LOC111146280Cyclic AMP-responsive element-binding protein 3. (353 aa)
LOC111146667Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
LOC111147321Cyclic AMP-responsive element-binding protein 5. (501 aa)
LOC111147575Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
LOC111146845Potassium channel subfamily K member. (374 aa)
LOC111148494Calmodulin-1 isoform X1; Belongs to the calmodulin family. (196 aa)
LOC1111500051-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1231 aa)
LOC111148267Calcium/calmodulin-dependent protein kinase type IV; Belongs to the protein kinase superfamily. (470 aa)
LOC111150407Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1984 aa)
LOC111150851Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
LOC111150877Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
LOC111150050Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
LOC111151183Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1233 aa)
LOC111151973Cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1. (520 aa)
LOC111149706Sn1-specific diacylglycerol lipase alpha. (1042 aa)
LOC111151233Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2369 aa)
LOC111152239Steroid 21-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (522 aa)
LOC111152174Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
LOC111152366Cyclic AMP-dependent transcription factor ATF-6 beta isoform X1. (718 aa)
LOC111152507Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
LOC111153362Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
LOC111150995Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
LOC111153498Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
LOC111154044Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
LOC111154200Potassium channel subfamily K member. (404 aa)
LOC111154189Pro-opiomelanocortin. (265 aa)
LOC111153268Calmodulin-like protein 4 isoform X1. (153 aa)
LOC111153485Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X3. (544 aa)
LOC111154752Natriuretic peptides A. (152 aa)
LOC111155859Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
LOC111156133Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
LOC111153427Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1093 aa)
LOC111154855Calmodulin-like protein 6. (212 aa)
LOC111153936G protein-activated inward rectifier potassium channel 4. (429 aa)
LOC111157525Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2187 aa)
LOC111157326Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
LOC111157825Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC111157882Nuclear receptor subfamily 4 group A member 1. (598 aa)
LOC111155044Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
LOC111156453Calcium release-activated calcium channel protein 1 isoform X1. (302 aa)
LOC111155531Calcium/calmodulin-dependent protein kinase type 1D; Belongs to the protein kinase superfamily. (385 aa)
LOC111158360Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (890 aa)
LOC111158606Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
LOC111157285Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (366 aa)
LOC111156013Voltage-dependent T-type calcium channel subunit alpha-1H. (2342 aa)
LOC111156379Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (509 aa)
LOC111157964Cyclic AMP-dependent transcription factor ATF-1 isoform X1. (329 aa)
LOC111159674Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2191 aa)
LOC111158087Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
LOC111159411Phosphodiesterase. (941 aa)
LOC111156985Calcium/calmodulin-dependent protein kinase type II subunit beta. (543 aa)
LOC111157054Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1138 aa)
LOC111160516Angiotensinogen; Belongs to the serpin family. (477 aa)
LOC111159979Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
LOC111157635Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
LOC111160605Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
LOC111161212Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
LOC111158594Calmodulin-like. (149 aa)
LOC111161440Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa)
LOC111161857Guanine nucleotide-binding protein subunit alpha-11. (353 aa)
LOC111162368Calcium/calmodulin-dependent protein kinase type 1G; Belongs to the protein kinase superfamily. (476 aa)
LOC111162516cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC111162438Low-density lipoprotein receptor. (839 aa)
LOC111161610Nuclear receptor subfamily 4 group A member 2 isoform X1. (598 aa)
LOC111161856Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1. (481 aa)
LOC111162403Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1113 aa)
LOC111161566Hormone-sensitive lipase isoform X1. (1064 aa)
LOC111162208Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC1111623021-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1220 aa)
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
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