STRINGSTRING
LOC111138817 LOC111138817 LOC111138866 LOC111138866 LOC111140316 LOC111140316 LOC111140276 LOC111140276 LOC111140421 LOC111140421 LOC111138943 LOC111138943 LOC111141288 LOC111141288 LOC111141620 LOC111141620 LOC111141312 LOC111141312 LOC111141396 LOC111141396 LOC111141563 LOC111141563 LOC111141614 LOC111141614 LOC111142967 LOC111142967 LOC111142895 LOC111142895 LOC111141432 LOC111141432 LOC111143000 LOC111143000 LOC111143174 LOC111143174 LOC111142759 LOC111142759 LOC111143470 LOC111143470 LOC111143783 LOC111143783 LOC111143029 LOC111143029 LOC111143790 LOC111143790 LOC111142203 LOC111142203 LOC111143238 LOC111143238 LOC111143343 LOC111143343 LOC111142395 LOC111142395 LOC111144322 LOC111144322 LOC111144339 LOC111144339 LOC111142901 LOC111142901 LOC111144860 LOC111144860 LOC111143399 LOC111143399 LOC111145586 LOC111145586 LOC111144833 LOC111144833 LOC111145828 LOC111145828 LOC111146071 LOC111146071 LOC111144527 LOC111144527 LOC111146280 LOC111146280 LOC111146667 LOC111146667 LOC111146901 LOC111146901 LOC111147281 LOC111147281 LOC111146994 LOC111146994 LOC111147321 LOC111147321 LOC111147037 LOC111147037 LOC111147545 LOC111147545 LOC111147575 LOC111147575 LOC111147726 LOC111147726 LOC111147195 LOC111147195 LOC111148079 LOC111148079 LOC111147333 LOC111147333 LOC111148588 LOC111148588 LOC111149705 LOC111149705 LOC111148765 LOC111148765 LOC111150005 LOC111150005 LOC111150885 LOC111150885 LOC111148602 LOC111148602 LOC111150050 LOC111150050 LOC111151317 LOC111151317 LOC111151537 LOC111151537 LOC111151973 LOC111151973 LOC111149566 LOC111149566 LOC111151818 LOC111151818 LOC111152183 LOC111152183 LOC111152267 LOC111152267 LOC111149956 LOC111149956 LOC111152366 LOC111152366 LOC111153611 LOC111153611 LOC111153766 LOC111153766 LOC111154016 LOC111154016 LOC111154044 LOC111154044 LOC111153158 LOC111153158 LOC111154402 LOC111154402 LOC111154565 LOC111154565 LOC111153623 LOC111153623 LOC111154601 LOC111154601 LOC111155003 LOC111155003 LOC111155312 LOC111155312 LOC111154641 LOC111154641 LOC111156133 LOC111156133 LOC111153427 LOC111153427 LOC111153761 LOC111153761 LOC111156411 LOC111156411 LOC111153845 LOC111153845 LOC111156207 LOC111156207 LOC111156738 LOC111156738 LOC111157042 LOC111157042 LOC111157184 LOC111157184 LOC111157326 LOC111157326 LOC111157825 LOC111157825 LOC111155044 LOC111155044 LOC111157625 LOC111157625 LOC111155224 LOC111155224 LOC111158354 LOC111158354 LOC111158557 LOC111158557 LOC111155743 LOC111155743 LOC111158999 LOC111158999 LOC111157628 LOC111157628 LOC111158087 LOC111158087 LOC111157054 LOC111157054 LOC111157340 LOC111157340 LOC111157367 LOC111157367 LOC111157635 LOC111157635 LOC111160889 LOC111160889 LOC111159618 LOC111159618 LOC111159773 LOC111159773 LOC111161165 LOC111161165 LOC111160835 LOC111160835 LOC111161271 LOC111161271 LOC111161374 LOC111161374 LOC111159984 LOC111159984 LOC111161718 LOC111161718 LOC111161815 LOC111161815 LOC111158897 LOC111158897 LOC111162137 LOC111162137 LOC111161723 LOC111161723 LOC111159444 LOC111159444 LOC111162401 LOC111162401 LOC111162516 LOC111162516 LOC111161210 LOC111161210 LOC111162236 LOC111162236 LOC111161277 LOC111161277 LOC111161420 LOC111161420 LOC111160411 LOC111160411 LOC111161743 LOC111161743 LOC111160502 LOC111160502 LOC111161856 LOC111161856 LOC111162403 LOC111162403 LOC111162432 LOC111162432 LOC111161808 LOC111161808 LOC111162302 LOC111162302
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111138817Collagen alpha-1(I) chain-like. (1136 aa)
LOC111138866SHC-transforming protein 1 isoform X1. (584 aa)
LOC111140316GTPase HRas isoform X1. (189 aa)
LOC111140276NF-kappa-B inhibitor alpha isoform X1. (358 aa)
LOC111140421Guanine nucleotide-binding protein subunit beta-5. (353 aa)
LOC111138943Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (384 aa)
LOC111141288Relaxin-3 receptor 1. (459 aa)
LOC1111416201-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
LOC111141312Neuroendocrine secretory protein 55. (249 aa)
LOC111141396Matrix metalloproteinase-9. (704 aa)
LOC111141563Tyrosine-protein kinase. (536 aa)
LOC111141614LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (1019 aa)
LOC111142967Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC111142895LOW QUALITY PROTEIN: insulin-like peptide INSL5. (140 aa)
LOC1111414321-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC111143000Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC111143174Transcription factor AP-1; Belongs to the bZIP family. (334 aa)
LOC111142759Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
LOC111143470Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa)
LOC111143783Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
LOC111143029Collagen alpha-4(IV) chain. (1688 aa)
LOC111143790Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa)
LOC111142203Collagen alpha-3(IV) chain. (1669 aa)
LOC111143238GTPase NRas. (189 aa)
LOC111143343Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
LOC111142395Mothers against decapentaplegic homolog. (467 aa)
LOC111144322RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
LOC111144339Insulin-like 3. (130 aa)
LOC111142901Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
LOC111144860Mitogen-activated protein kinase. (427 aa)
LOC111143399cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
LOC111145586Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X1. (340 aa)
LOC111144833Actin, aortic smooth muscle. (377 aa)
LOC111145828Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC111146071Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
LOC111144527Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (421 aa)
LOC111146280Cyclic AMP-responsive element-binding protein 3. (353 aa)
LOC111146667Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
LOC111146901Collagen alpha-1(IV) chain. (1679 aa)
LOC111147281Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
LOC111146994Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (443 aa)
LOC111147321Cyclic AMP-responsive element-binding protein 5. (501 aa)
LOC111147037Collagen alpha-2(IV) chain. (1711 aa)
LOC111147545Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC111147575Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
LOC111147726Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (572 aa)
LOC111147195Collagen alpha-2(I) chain. (1367 aa)
LOC111148079Collagen alpha-1(III) chain. (1466 aa)
LOC111147333Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
LOC111148588Guanine nucleotide-binding protein subunit beta-4. (340 aa)
LOC111149705Vascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (207 aa)
LOC111148765Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC1111500051-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1231 aa)
LOC111150885Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC111148602Proto-oncogene c-Fos. (380 aa)
LOC111150050Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
LOC111151317Collagen alpha-1(I) chain isoform X1. (1460 aa)
LOC111151537Nitric oxide synthase; Produces nitric oxide (NO). (1157 aa)
LOC111151973Cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1. (520 aa)
LOC111149566Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC111151818Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
LOC111152183Mitogen-activated protein kinase. (360 aa)
LOC111152267Mitogen-activated protein kinase. (366 aa)
LOC111149956Transcription factor p65. (542 aa)
LOC111152366Cyclic AMP-dependent transcription factor ATF-6 beta isoform X1. (718 aa)
LOC111153611Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa)
LOC111153766Interstitial collagenase. (470 aa)
LOC111154016Mitogen-activated protein kinase. (464 aa)
LOC111154044Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
LOC111153158Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LOC111154402Nitric oxide synthase; Produces nitric oxide (NO). (1211 aa)
LOC111154565Protein kinase C zeta type isoform X1. (646 aa)
LOC111153623SHC-transforming protein 3. (587 aa)
LOC111154601Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
LOC111155003LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC111155312Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
LOC111154641Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
LOC111156133Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
LOC111153427Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1093 aa)
LOC111153761Collagenase 3. (474 aa)
LOC111156411Nitric oxide synthase; Produces nitric oxide (NO). (1433 aa)
LOC111153845Interstitial collagenase-like. (453 aa)
LOC111156207Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
LOC111156738Endothelin-1. (202 aa)
LOC111157042Receptor protein-tyrosine kinase. (1154 aa)
LOC111157184Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
LOC111157326Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
LOC111157825Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC111155044Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
LOC111157625Mitogen-activated protein kinase. (364 aa)
LOC111155224Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
LOC111158354Son of sevenless homolog 1 isoform X2. (1333 aa)
LOC111158557Relaxin receptor 2. (737 aa)
LOC111155743Relaxin receptor 1. (758 aa)
LOC111158999TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
LOC111157628Mitogen-activated protein kinase 12 isoform X1. (486 aa)
LOC111158087Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
LOC111157054Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1138 aa)
LOC11115734072 kDa type IV collagenase. (661 aa)
LOC111157367Guanine nucleotide-binding protein G(O) subunit alpha. (354 aa)
LOC111157635Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
LOC111160889Son of sevenless homolog 2 isoform X1. (1332 aa)
LOC111159618Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (96 aa)
LOC111159773Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
LOC111161165Beta-arrestin-2 isoform X1. (522 aa)
LOC111160835Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC111161271Collagen alpha-5(IV) chain. (1691 aa)
LOC111161374Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC111159984GTPase KRas isoform X1. (227 aa)
LOC111161718Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC111161815Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
LOC111158897Mitogen-activated protein kinase 9 isoform X1. (443 aa)
LOC111162137SHC-transforming protein 4. (623 aa)
LOC111161723Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
LOC111159444Beta-arrestin-1 isoform X1. (418 aa)
LOC111162401Relaxin-3. (140 aa)
LOC111162516cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC111161210Dual specificity mitogen-activated protein kinase kinase 4 isoform X2; Belongs to the protein kinase superfamily. (411 aa)
LOC111162236Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (372 aa)
LOC111161277Collagen alpha-6(IV) chain. (1721 aa)
LOC111161420Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
LOC111160411Growth factor receptor-bound protein 2. (217 aa)
LOC111161743Guanine nucleotide-binding protein subunit alpha-15. (374 aa)
LOC111160502Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC111161856Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1. (481 aa)
LOC111162403Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1113 aa)
LOC111162432Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC111161808SHC-transforming protein 2. (583 aa)
LOC1111623021-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1220 aa)
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
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