STRINGSTRING
LOC111138943 LOC111138943 LOC111141620 LOC111141620 LOC111141312 LOC111141312 LOC111141614 LOC111141614 LOC111142750 LOC111142750 LOC111141432 LOC111141432 LOC111143738 LOC111143738 LOC111144498 LOC111144498 LOC111142901 LOC111142901 LOC111143399 LOC111143399 LOC111143436 LOC111143436 LOC111144005 LOC111144005 LOC111146280 LOC111146280 LOC111146667 LOC111146667 LOC111145221 LOC111145221 LOC111147321 LOC111147321 LOC111147575 LOC111147575 LOC111148266 LOC111148266 LOC111146254 LOC111146254 LOC111146729 LOC111146729 LOC111149950 LOC111149950 LOC111150005 LOC111150005 LOC111149992 LOC111149992 LOC111150569 LOC111150569 LOC111150407 LOC111150407 LOC111150823 LOC111150823 LOC111150851 LOC111150851 LOC111150050 LOC111150050 LOC111151184 LOC111151184 LOC111151973 LOC111151973 LOC111151233 LOC111151233 LOC111152239 LOC111152239 LOC111152366 LOC111152366 LOC111152507 LOC111152507 LOC111152625 LOC111152625 LOC111153362 LOC111153362 LOC111150995 LOC111150995 LOC111153498 LOC111153498 LOC111154044 LOC111154044 LOC111154200 LOC111154200 LOC111154189 LOC111154189 LOC111156133 LOC111156133 LOC111153427 LOC111153427 LOC111157525 LOC111157525 LOC111157326 LOC111157326 LOC111157825 LOC111157825 LOC111157882 LOC111157882 LOC111155044 LOC111155044 LOC111156453 LOC111156453 LOC111155664 LOC111155664 LOC111156013 LOC111156013 LOC111156379 LOC111156379 LOC111157856 LOC111157856 LOC111159674 LOC111159674 LOC111157054 LOC111157054 LOC111160516 LOC111160516 LOC111159979 LOC111159979 LOC111157635 LOC111157635 LOC111161857 LOC111161857 LOC111162516 LOC111162516 LOC111162438 LOC111162438 LOC111161856 LOC111161856 LOC111162403 LOC111162403 LOC111162302 LOC111162302
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111138943Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (384 aa)
LOC1111416201-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
LOC111141312Neuroendocrine secretory protein 55. (249 aa)
LOC111141614LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (1019 aa)
LOC111142750Adrenocorticotropic hormone receptor. (297 aa)
LOC1111414321-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC111143738Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
LOC111144498Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
LOC111142901Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
LOC111143399cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
LOC1111434363 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; Belongs to the 3-beta-HSD family. (373 aa)
LOC111144005Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa)
LOC111146280Cyclic AMP-responsive element-binding protein 3. (353 aa)
LOC111146667Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
LOC111145221Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family. (508 aa)
LOC111147321Cyclic AMP-responsive element-binding protein 5. (501 aa)
LOC111147575Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
LOC111148266Phosphodiesterase. (891 aa)
LOC111146254Steroidogenic factor 1. (461 aa)
LOC111146729Cytochrome P450 11B1, mitochondrial-like isoform X1; Belongs to the cytochrome P450 family. (503 aa)
LOC111149950Neutral cholesterol ester hydrolase 1. (408 aa)
LOC1111500051-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1231 aa)
LOC111149992Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (654 aa)
LOC111150569Nuclear receptor subfamily 0 group B member 1. (471 aa)
LOC111150407Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1984 aa)
LOC111150823Potassium channel subfamily K member 2 isoform X1; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (443 aa)
LOC111150851Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
LOC111150050Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
LOC111151184pre-B-cell leukemia transcription factor 1 isoform X1. (430 aa)
LOC111151973Cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1. (520 aa)
LOC111151233Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2369 aa)
LOC111152239Steroid 21-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (522 aa)
LOC111152366Cyclic AMP-dependent transcription factor ATF-6 beta isoform X1. (718 aa)
LOC111152507Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
LOC111152625Phosphodiesterase. (830 aa)
LOC111153362Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
LOC111150995Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
LOC111153498Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
LOC111154044Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
LOC111154200Potassium channel subfamily K member. (404 aa)
LOC111154189Pro-opiomelanocortin. (265 aa)
LOC111156133Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
LOC111153427Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1093 aa)
LOC111157525Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2187 aa)
LOC111157326Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
LOC111157825Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC111157882Nuclear receptor subfamily 4 group A member 1. (598 aa)
LOC111155044Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
LOC111156453Calcium release-activated calcium channel protein 1 isoform X1. (302 aa)
LOC111155664Melanocortin-2 receptor accessory protein. (138 aa)
LOC111156013Voltage-dependent T-type calcium channel subunit alpha-1H. (2342 aa)
LOC111156379Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (509 aa)
LOC111157856Transcription factor Sp1 isoform X1. (786 aa)
LOC111159674Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2191 aa)
LOC111157054Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1138 aa)
LOC111160516Angiotensinogen; Belongs to the serpin family. (477 aa)
LOC111159979Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
LOC111157635Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
LOC111161857Guanine nucleotide-binding protein subunit alpha-11. (353 aa)
LOC111162516cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC111162438Low-density lipoprotein receptor. (839 aa)
LOC111161856Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1. (481 aa)
LOC111162403Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1113 aa)
LOC1111623021-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1220 aa)
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
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