79 items (Enhydra lutris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111138822	Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
	LOC111138823	Sodium/potassium-transporting ATPase subunit alpha. (1031 aa)
	LOC111139156	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1227 aa)
	LOC111139318	Lysozyme-like protein 1; Belongs to the glycosyl hydrolase 22 family. (148 aa)
	LOC111139613	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
	LOC111139490	Sodium/potassium-transporting ATPase subunit alpha. (1014 aa)
	LOC111139532	Intermediate conductance calcium-activated potassium channel protein 4. (526 aa)
	LOC111140904	Solute carrier family 12 member 2 isoform X1. (1204 aa)
	LOC111141132	alpha-1B adrenergic receptor. (518 aa)
	LOC111141546	cystatin-C; Belongs to the cystatin family. (145 aa)
	LOC111141765	alpha-1D adrenergic receptor. (571 aa)
	LOC111140999	Beta-2 adrenergic receptor. (418 aa)
	LOC111141620	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
	LOC111141312	Neuroendocrine secretory protein 55. (249 aa)
	LOC111140152	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (697 aa)
	LOC111141614	LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (1019 aa)
	LOC111142811	Alpha-amylase. (529 aa)
	LOC111142249	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
	LOC111141432	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
	LOC111143264	Sodium/potassium-transporting ATPase subunit alpha. (1051 aa)
	LOC111141981	Lysozyme; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Belongs to the glycosyl hydrolase 22 family. (148 aa)
	LOC111144584	LOW QUALITY PROTEIN: beta-3 adrenergic receptor-like. (602 aa)
	LOC111144054	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
	LOC111144247	Cathelicidin antimicrobial peptide. (168 aa)
	LOC111145151	CUB and zona pellucida-like domain-containing protein 1. (608 aa)
	LOC111143399	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
	LOC111144973	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (626 aa)
	LOC111145040	LOW QUALITY PROTEIN: deleted in malignant brain tumors 1 protein. (2780 aa)
	LOC111144685	Calcium-activated potassium channel subunit alpha-1 isoform X2. (1263 aa)
	LOC111145213	cGMP-dependent protein kinase. (686 aa)
	LOC111144005	Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa)
	LOC111145258	Beta-1 adrenergic receptor. (466 aa)
	LOC111146667	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
	LOC111147095	LOW QUALITY PROTEIN: guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (707 aa)
	LOC111148494	Calmodulin-1 isoform X1; Belongs to the calmodulin family. (196 aa)
	LOC111149117	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 isoform X1. (307 aa)
	LOC111149130	cGMP-dependent protein kinase. (762 aa)
	LOC111149296	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1. (305 aa)
	LOC111149474	LOW QUALITY PROTEIN: mucin-5B. (4174 aa)
	LOC111149370	Mucin-7. (255 aa)
	LOC111150005	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1231 aa)
	LOC111150877	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
	LOC111151183	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1233 aa)
	LOC111151504	Lactoperoxidase isoform X1. (712 aa)
	LOC111152044	Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (724 aa)
	LOC111152174	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
	LOC111152507	Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
	LOC111153498	Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
	LOC111153821	LOW QUALITY PROTEIN: guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (737 aa)
	LOC111154115	Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
	LOC111154044	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
	LOC111154322	Anion exchange protein. (1238 aa)
	LOC111153268	Calmodulin-like protein 4 isoform X1. (153 aa)
	LOC111153819	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
	LOC111155838	Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
	LOC111156133	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
	LOC111153427	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1093 aa)
	LOC111154855	Calmodulin-like protein 6. (212 aa)
	LOC111156411	Nitric oxide synthase; Produces nitric oxide (NO). (1433 aa)
	LOC111156412	alpha-1A adrenergic receptor. (466 aa)
	LOC111157326	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
	LOC111157825	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
	LOC111155044	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
	LOC111157901	Aquaporin-5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
	LOC111158606	Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
	LOC111157285	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (366 aa)
	LOC111159558	Ryanodine receptor 3. (4849 aa)
	LOC111158087	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
	LOC111157054	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1138 aa)
	LOC111159979	Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
	LOC111157867	Lysozyme C, milk isozyme; Belongs to the glycosyl hydrolase 22 family. (148 aa)
	LOC111161212	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
	LOC111158594	Calmodulin-like. (149 aa)
	LOC111162516	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
	LOC111161127	Vesicle-associated membrane protein 2. (116 aa)
	LOC111162403	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1113 aa)
	LOC111162529	Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (508 aa)
	LOC111162208	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
	LOC111162302	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1220 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111138822	LOC111138823	A0A2Y9ICK9	A0A2Y9ICS7	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
LOC111138822	LOC111139490	A0A2Y9ICK9	A0A2Y9IGL5	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.900
LOC111138822	LOC111143264	A0A2Y9ICK9	A0A2Y9IVB9	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.900
LOC111138822	LOC111143399	A0A2Y9ICK9	A0A2Y9J431	Sodium/potassium-transporting ATPase subunit alpha.	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	0.909
LOC111138822	LOC111145213	A0A2Y9ICK9	A0A2Y9J542	Sodium/potassium-transporting ATPase subunit alpha.	cGMP-dependent protein kinase.	0.908
LOC111138822	LOC111149130	A0A2Y9ICK9	A0A2Y9JLE0	Sodium/potassium-transporting ATPase subunit alpha.	cGMP-dependent protein kinase.	0.903
LOC111138822	LOC111150877	A0A2Y9ICK9	A0A2Y9JTE2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.982
LOC111138822	LOC111152174	A0A2Y9ICK9	A0A2Y9JZE6	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.968
LOC111138822	LOC111153819	A0A2Y9ICK9	A0A2Y9KB13	Sodium/potassium-transporting ATPase subunit alpha.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.972
LOC111138822	LOC111157285	A0A2Y9ICK9	A0A2Y9KSQ4	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.963
LOC111138822	LOC111161212	A0A2Y9ICK9	A0A2Y9L2N2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.970
LOC111138822	LOC111162516	A0A2Y9ICK9	A0A2Y9L9E0	Sodium/potassium-transporting ATPase subunit alpha.	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.	0.909
LOC111138823	LOC111138822	A0A2Y9ICS7	A0A2Y9ICK9	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
LOC111138823	LOC111139490	A0A2Y9ICS7	A0A2Y9IGL5	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
LOC111138823	LOC111143264	A0A2Y9ICS7	A0A2Y9IVB9	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
LOC111138823	LOC111143399	A0A2Y9ICS7	A0A2Y9J431	Sodium/potassium-transporting ATPase subunit alpha.	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	0.909
LOC111138823	LOC111145213	A0A2Y9ICS7	A0A2Y9J542	Sodium/potassium-transporting ATPase subunit alpha.	cGMP-dependent protein kinase.	0.908
LOC111138823	LOC111149130	A0A2Y9ICS7	A0A2Y9JLE0	Sodium/potassium-transporting ATPase subunit alpha.	cGMP-dependent protein kinase.	0.903
LOC111138823	LOC111150877	A0A2Y9ICS7	A0A2Y9JTE2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.981
LOC111138823	LOC111152174	A0A2Y9ICS7	A0A2Y9JZE6	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.967