101 items (Enhydra lutris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111138822	Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
	LOC111138823	Sodium/potassium-transporting ATPase subunit alpha. (1031 aa)
	LOC111139156	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1227 aa)
	LOC111139613	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
	LOC111139490	Sodium/potassium-transporting ATPase subunit alpha. (1014 aa)
	LOC111140904	Solute carrier family 12 member 2 isoform X1. (1204 aa)
	LOC111140403	Cationic trypsin-like; Belongs to the peptidase S1 family. (246 aa)
	LOC111140948	Secretin receptor; Belongs to the G-protein coupled receptor 2 family. (449 aa)
	LOC111141620	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
	LOC111141969	Ras-related protein Rap-1b. (184 aa)
	LOC111141312	Neuroendocrine secretory protein 55. (249 aa)
	LOC111140152	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (697 aa)
	LOC111140394	Cationic trypsin-like; Belongs to the peptidase S1 family. (241 aa)
	LOC111141614	LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (1019 aa)
	LOC111142811	Alpha-amylase. (529 aa)
	LOC111142249	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
	LOC111141432	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
	LOC111143264	Sodium/potassium-transporting ATPase subunit alpha. (1051 aa)
	LOC111143553	Calcium-activated chloride channel regulator 2. (943 aa)
	LOC111143716	Calcium-activated chloride channel regulator 1-like. (905 aa)
	LOC111144026	Transforming protein RhoA isoform X1. (193 aa)
	LOC111144096	Ras-related protein Rab-8A. (207 aa)
	LOC111142912	LOW QUALITY PROTEIN: calcium-activated chloride channel regulator 4-like. (1025 aa)
	LOC111144054	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
	LOC111144745	LOW QUALITY PROTEIN: ryanodine receptor 2. (5099 aa)
	LOC111143365	Calcium-activated chloride channel regulator 1. (911 aa)
	LOC111144973	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (626 aa)
	LOC111145145	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (469 aa)
	LOC111144685	Calcium-activated potassium channel subunit alpha-1 isoform X2. (1263 aa)
	LOC111145232	Group XIIB secretory phospholipase A2-like protein isoform X1. (195 aa)
	LOC111143648	Ras-related protein Rap-1A isoform X1. (184 aa)
	LOC111144005	Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa)
	LOC111145636	Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa)
	LOC111146638	Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
	LOC111146667	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
	LOC111144940	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (467 aa)
	LOC111144944	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (465 aa)
	LOC111145589	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (599 aa)
	LOC111148061	Short transient receptor potential channel 1 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
	LOC111147955	Carboxypeptidase B. (417 aa)
	LOC111148385	Ras-related protein Rab-11A-like isoform X1. (216 aa)
	LOC111148909	Anion exchange protein. (1081 aa)
	LOC111149117	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 isoform X1. (307 aa)
	LOC111147094	Carboxypeptidase B2. (423 aa)
	LOC111149296	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1. (305 aa)
	LOC111149602	Two pore calcium channel protein 2 isoform X1. (747 aa)
	LOC111150000	Secretin. (131 aa)
	LOC111150005	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1231 aa)
	LOC111149772	Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (667 aa)
	LOC111149244	Cholecystokinin receptor type A; Belongs to the G-protein coupled receptor 1 family. (428 aa)
	LOC111149487	Two pore calcium channel protein 2-like. (204 aa)
	LOC111150877	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
	LOC111151183	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1233 aa)
	LOC111151528	Mast cell carboxypeptidase A isoform X2. (417 aa)
	LOC111151955	Carboxypeptidase A2. (417 aa)
	LOC111151863	Carboxypeptidase A1. (419 aa)
	LOC111151952	Anionic trypsin; Belongs to the peptidase S1 family. (247 aa)
	LOC111152174	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
	LOC111152507	Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
	LOC111152797	Chymotrypsinogen 2 isoform X1; Belongs to the peptidase S1 family. (263 aa)
	LOC111152844	Chymotrypsin-like protease CTRL-1; Belongs to the peptidase S1 family. (264 aa)
	LOC111151957	Cationic trypsin isoform X1; Belongs to the peptidase S1 family. (246 aa)
	LOC111153498	Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
	LOC111154044	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
	LOC111152908	Chymotrypsinogen 2-like; Belongs to the peptidase S1 family. (150 aa)
	LOC111154322	Anion exchange protein. (1238 aa)
	LOC111153069	LOW QUALITY PROTEIN: chymotrypsinogen B-like; Belongs to the peptidase S1 family. (372 aa)
	LOC111154292	Ras-related protein Rab-27B. (225 aa)
	LOC111152043	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1484 aa)
	LOC111154927	Phospholipase A(2). (211 aa)
	LOC111153819	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
	LOC111154568	Chymotrypsin-like elastase family member 3B; Belongs to the peptidase S1 family. (280 aa)
	LOC111156133	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
	LOC111153427	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1093 aa)
	LOC111154930	Phospholipase A(2). (170 aa)
	LOC111156318	Phospholipase A(2). (148 aa)
	LOC111155325	Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (791 aa)
	LOC111154579	Phospholipase A(2). (142 aa)
	LOC111154809	Phospholipase A(2). (137 aa)
	LOC111157326	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
	LOC111157825	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
	LOC111154917	Phospholipase A(2). (145 aa)
	LOC111156353	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
	LOC111155044	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
	LOC111158763	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (942 aa)
	LOC111157285	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (366 aa)
	LOC111159120	Cholecystokinin. (115 aa)
	LOC111156262	Phospholipase A(2). (159 aa)
	LOC111157595	Group XIIA secretory phospholipase A2. (190 aa)
	LOC111159008	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1013 aa)
	LOC111158087	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
	LOC111160096	Group 3 secretory phospholipase A2. (513 aa)
	LOC111157054	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1138 aa)
	LOC111159979	Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
	LOC111161212	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
	LOC111159970	Ras-related protein Rab-11A isoform X1. (216 aa)
	LOC111162473	Ras-related protein Rab-3D. (219 aa)
	LOC111162403	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1113 aa)
	LOC111162208	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
	LOC111162286	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1008 aa)
	LOC111162302	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1220 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111138822	LOC111138823	A0A2Y9ICK9	A0A2Y9ICS7	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
LOC111138822	LOC111139490	A0A2Y9ICK9	A0A2Y9IGL5	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.900
LOC111138822	LOC111143264	A0A2Y9ICK9	A0A2Y9IVB9	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.900
LOC111138822	LOC111150877	A0A2Y9ICK9	A0A2Y9JTE2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.982
LOC111138822	LOC111152174	A0A2Y9ICK9	A0A2Y9JZE6	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.968
LOC111138822	LOC111153819	A0A2Y9ICK9	A0A2Y9KB13	Sodium/potassium-transporting ATPase subunit alpha.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.972
LOC111138822	LOC111157285	A0A2Y9ICK9	A0A2Y9KSQ4	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.963
LOC111138822	LOC111161212	A0A2Y9ICK9	A0A2Y9L2N2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.970
LOC111138823	LOC111138822	A0A2Y9ICS7	A0A2Y9ICK9	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
LOC111138823	LOC111139490	A0A2Y9ICS7	A0A2Y9IGL5	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
LOC111138823	LOC111143264	A0A2Y9ICS7	A0A2Y9IVB9	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
LOC111138823	LOC111150877	A0A2Y9ICS7	A0A2Y9JTE2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.981
LOC111138823	LOC111152174	A0A2Y9ICS7	A0A2Y9JZE6	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.967
LOC111138823	LOC111153819	A0A2Y9ICS7	A0A2Y9KB13	Sodium/potassium-transporting ATPase subunit alpha.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.972
LOC111138823	LOC111157285	A0A2Y9ICS7	A0A2Y9KSQ4	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.963
LOC111138823	LOC111161212	A0A2Y9ICS7	A0A2Y9L2N2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.970
LOC111139156	LOC111143264	A0A2Y9IEB1	A0A2Y9IVB9	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Sodium/potassium-transporting ATPase subunit alpha.	0.486
LOC111139156	LOC111150877	A0A2Y9IEB1	A0A2Y9JTE2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.439
LOC111139156	LOC111152174	A0A2Y9IEB1	A0A2Y9JZE6	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.492
LOC111139156	LOC111153819	A0A2Y9IEB1	A0A2Y9KB13	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.408