STRINGSTRING
LOC111139191 LOC111139191 LOC111139240 LOC111139240 LOC111139287 LOC111139287 LOC111140316 LOC111140316 LOC111140276 LOC111140276 LOC111140724 LOC111140724 LOC111141423 LOC111141423 LOC111142881 LOC111142881 LOC111143133 LOC111143133 LOC111141414 LOC111141414 LOC111142990 LOC111142990 LOC111143174 LOC111143174 LOC111141582 LOC111141582 LOC111142759 LOC111142759 LOC111143470 LOC111143470 LOC111143790 LOC111143790 LOC111142126 LOC111142126 LOC111143238 LOC111143238 LOC111144322 LOC111144322 LOC111144778 LOC111144778 LOC111144797 LOC111144797 LOC111144921 LOC111144921 LOC111144397 LOC111144397 LOC111144592 LOC111144592 LOC111143741 LOC111143741 LOC111144043 LOC111144043 LOC111146053 LOC111146053 LOC111147545 LOC111147545 LOC111147686 LOC111147686 LOC111146042 LOC111146042 LOC111148765 LOC111148765 LOC111149588 LOC111149588 LOC111147725 LOC111147725 LOC111148007 LOC111148007 LOC111150027 LOC111150027 LOC111150885 LOC111150885 LOC111148602 LOC111148602 LOC111148636 LOC111148636 LOC111150748 LOC111150748 LOC111152166 LOC111152166 LOC111152183 LOC111152183 LOC111152267 LOC111152267 LOC111149956 LOC111149956 LOC111150237 LOC111150237 LOC111151757 LOC111151757 LOC111150901 LOC111150901 LOC111153609 LOC111153609 LOC111153611 LOC111153611 LOC111153517 LOC111153517 LOC111151241 LOC111151241 LOC111152752 LOC111152752 LOC111153842 LOC111153842 LOC111153868 LOC111153868 LOC111153962 LOC111153962 LOC111154209 LOC111154209 LOC111153158 LOC111153158 LOC111154144 LOC111154144 LOC111154566 LOC111154566 LOC111153823 LOC111153823 LOC111154734 LOC111154734 LOC111155003 LOC111155003 LOC111155682 LOC111155682 LOC111154641 LOC111154641 LOC111155922 LOC111155922 LOC111154883 LOC111154883 LOC111156454 LOC111156454 LOC111157042 LOC111157042 LOC111154862 LOC111154862 LOC111158066 LOC111158066 LOC111157625 LOC111157625 LOC111155224 LOC111155224 LOC111158506 LOC111158506 LOC111159049 LOC111159049 LOC111157628 LOC111157628 LOC111156359 LOC111156359 LOC111158041 LOC111158041 LOC111159821 LOC111159821 LOC111157353 LOC111157353 LOC111161374 LOC111161374 LOC111159984 LOC111159984 LOC111161594 LOC111161594 LOC111158618 LOC111158618 LOC111161725 LOC111161725 LOC111161815 LOC111161815 LOC111158884 LOC111158884 LOC111159390 LOC111159390 LOC111162219 LOC111162219 LOC111159680 LOC111159680 LOC111162236 LOC111162236
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111139191NF-kappa-B essential modulator. (412 aa)
LOC111139240Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
LOC111139287Tyrosine-protein kinase receptor. (1627 aa)
LOC111140316GTPase HRas isoform X1. (189 aa)
LOC111140276NF-kappa-B inhibitor alpha isoform X1. (358 aa)
LOC111140724RAS guanyl-releasing protein 1 isoform X1. (797 aa)
LOC1111414231-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
LOC111142881Tyrosine-protein kinase. (1153 aa)
LOC111143133Programmed cell death protein 1. (288 aa)
LOC111141414Casein kinase II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (391 aa)
LOC111142990Tyrosine-protein kinase. (509 aa)
LOC111143174Transcription factor AP-1; Belongs to the bZIP family. (334 aa)
LOC111141582LOW QUALITY PROTEIN: nuclear factor of activated T-cells, cytoplasmic 2. (912 aa)
LOC111142759Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
LOC111143470Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa)
LOC111143790Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa)
LOC111142126Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
LOC111143238GTPase NRas. (189 aa)
LOC111144322RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
LOC111144778Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (388 aa)
LOC111144797Serine/threonine-protein phosphatase. (534 aa)
LOC111144921Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
LOC111144397Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
LOC111144592Signal transducer and activator of transcription. (750 aa)
LOC111143741Toll-like receptor 9 isoform X1. (1327 aa)
LOC111144043T-cell-specific surface glycoprotein CD28. (255 aa)
LOC111146053Calcineurin subunit B type 2. (170 aa)
LOC111147545Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC111147686Interferon gamma receptor 1. (474 aa)
LOC111146042Toll-like receptor 4 isoform X1; Belongs to the Toll-like receptor family. (833 aa)
LOC111148765Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC111149588Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (491 aa)
LOC111147725NF-kappa-B inhibitor epsilon. (362 aa)
LOC111148007Calcineurin subunit B type 1. (170 aa)
LOC111150027TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
LOC111150885Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC111148602Proto-oncogene c-Fos. (380 aa)
LOC111148636Basic leucine zipper transcriptional factor ATF-like. (125 aa)
LOC111150748T-cell surface glycoprotein CD3 zeta chain isoform X1. (185 aa)
LOC111152166Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
LOC111152183Mitogen-activated protein kinase. (360 aa)
LOC111152267Mitogen-activated protein kinase. (366 aa)
LOC111149956Transcription factor p65. (542 aa)
LOC111150237Basic leucine zipper transcriptional factor ATF-like 2. (275 aa)
LOC111151757Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
LOC111150901Basic leucine zipper transcriptional factor ATF-like 3. (122 aa)
LOC111153609Programmed cell death 1 ligand 1. (303 aa)
LOC111153611Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa)
LOC111153517Tyrosine-protein kinase. (974 aa)
LOC111151241Signal transducer and activator of transcription. (802 aa)
LOC111152752Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1107 aa)
LOC111153842T-cell surface glycoprotein CD3 gamma chain. (180 aa)
LOC111153868Toll/interleukin-1 receptor domain-containing adapter protein. (227 aa)
LOC111153962T-cell surface glycoprotein CD3 epsilon chain isoform X1. (192 aa)
LOC111154209Nuclear factor of activated T-cells, cytoplasmic 1 isoform X1. (931 aa)
LOC111153158Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LOC111154144Serine/threonine-protein phosphatase. (534 aa)
LOC111154566Serine/threonine-protein phosphatase. (521 aa)
LOC111153823T-cell surface glycoprotein CD3 delta chain isoform X1. (169 aa)
LOC111154734Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa)
LOC111155003LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC111155682Interferon gamma receptor 2 isoform X2. (353 aa)
LOC111154641Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
LOC111155922Tyrosine-protein kinase. (616 aa)
LOC111154883Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
LOC111156454Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
LOC111157042Receptor protein-tyrosine kinase. (1154 aa)
LOC111154862LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 11-like. (711 aa)
LOC111158066Mitogen-activated protein kinase kinase kinase 3 isoform X1. (657 aa)
LOC111157625Mitogen-activated protein kinase. (364 aa)
LOC111155224Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
LOC111158506Echinoderm microtubule-associated protein-like 4 isoform X1. (992 aa)
LOC111159049Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
LOC111157628Mitogen-activated protein kinase 12 isoform X1. (486 aa)
LOC111156359Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
LOC111158041Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (334 aa)
LOC111159821T-cell surface glycoprotein CD4 isoform X1. (463 aa)
LOC111157353Casein kinase II subunit alpha' isoform X1; Belongs to the protein kinase superfamily. (350 aa)
LOC111161374Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC111159984GTPase KRas isoform X1. (227 aa)
LOC111161594NF-kappa-B inhibitor beta. (354 aa)
LOC111158618Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
LOC111161725TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (763 aa)
LOC111161815Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
LOC111158884TIR domain-containing adapter molecule 2. (243 aa)
LOC111159390Hypoxia-inducible factor 1-alpha isoform X1. (823 aa)
LOC111162219Linker for activation of T-cells family member 1 isoform X1. (260 aa)
LOC111159680Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
LOC111162236Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (372 aa)
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
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