STRINGSTRING
LOC111138934 LOC111138934 LOC111139159 LOC111139159 LOC111138967 LOC111138967 LOC111139592 LOC111139592 LOC111139628 LOC111139628 LOC111140770 LOC111140770 LOC111139627 LOC111139627 LOC111141476 LOC111141476 LOC111141135 LOC111141135 LOC111141155 LOC111141155 LOC111140065 LOC111140065 LOC111141312 LOC111141312 LOC111142308 LOC111142308 LOC111142036 LOC111142036 LOC111141614 LOC111141614 LOC111142293 LOC111142293 LOC111142456 LOC111142456 LOC111143738 LOC111143738 LOC111143852 LOC111143852 LOC111144160 LOC111144160 LOC111143872 LOC111143872 LOC111144745 LOC111144745 LOC111144193 LOC111144193 LOC111143399 LOC111143399 LOC111145591 LOC111145591 LOC111143787 LOC111143787 LOC111145258 LOC111145258 LOC111144138 LOC111144138 LOC111144250 LOC111144250 LOC111146667 LOC111146667 LOC111147337 LOC111147337 LOC111147537 LOC111147537 LOC111145734 LOC111145734 LOC111147662 LOC111147662 LOC111148610 LOC111148610 LOC111149236 LOC111149236 LOC111148592 LOC111148592 LOC111149549 LOC111149549 LOC111150407 LOC111150407 LOC111151009 LOC111151009 LOC111151581 LOC111151581 LOC111151764 LOC111151764 LOC111153107 LOC111153107 LOC111153129 LOC111153129 LOC111150995 LOC111150995 LOC111152248 LOC111152248 LOC111151068 LOC111151068 LOC111153536 LOC111153536 LOC111154044 LOC111154044 LOC111151650 LOC111151650 LOC111151669 LOC111151669 LOC111155029 LOC111155029 LOC111155043 LOC111155043 LOC111155265 LOC111155265 LOC111155558 LOC111155558 LOC111155529 LOC111155529 LOC111156133 LOC111156133 LOC111153427 LOC111153427 LOC111156317 LOC111156317 LOC111155505 LOC111155505 LOC111157697 LOC111157697 LOC111157326 LOC111157326 LOC111157825 LOC111157825 LOC111157805 LOC111157805 LOC111156353 LOC111156353 LOC111155044 LOC111155044 LOC111157949 LOC111157949 LOC111158126 LOC111158126 LOC111158107 LOC111158107 LOC111157851 LOC111157851 LOC111158430 LOC111158430 LOC111158195 LOC111158195 LOC111158763 LOC111158763 LOC111159088 LOC111159088 LOC111159692 LOC111159692 LOC111159008 LOC111159008 LOC111159674 LOC111159674 LOC111157054 LOC111157054 LOC111158552 LOC111158552 LOC111160249 LOC111160249 LOC111160516 LOC111160516 LOC111158831 LOC111158831 LOC111160156 LOC111160156 LOC111158197 LOC111158197 LOC111160727 LOC111160727 LOC111158207 LOC111158207 LOC111160262 LOC111160262 LOC111160297 LOC111160297 LOC111162005 LOC111162005 LOC111162516 LOC111162516 LOC111159921 LOC111159921 LOC111161420 LOC111161420 LOC111162323 LOC111162323 LOC111162403 LOC111162403 LOC111162286 LOC111162286
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111138934Lamin isoform X1; Belongs to the intermediate filament family. (751 aa)
LOC111139159Emerin. (260 aa)
LOC111138967Tropomyosin alpha-3 chain isoform X3; Belongs to the tropomyosin family. (284 aa)
LOC111139592Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (457 aa)
LOC111139628Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (260 aa)
LOC111140770Integrin alpha-1; Belongs to the integrin alpha chain family. (1217 aa)
LOC111139627Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
LOC111141476Voltage-dependent L-type calcium channel subunit beta-4 isoform X1. (519 aa)
LOC111141135Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa)
LOC111141155Delta-sarcoglycan. (289 aa)
LOC111140065Troponin I, cardiac muscle isoform X1. (211 aa)
LOC111141312Neuroendocrine secretory protein 55. (249 aa)
LOC111142308Integrin beta; Belongs to the integrin beta chain family. (808 aa)
LOC111142036Insulin-like growth factor I isoform X1. (183 aa)
LOC111141614LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (1019 aa)
LOC111142293Insulin-like growth factor I. (207 aa)
LOC111142456Laminin subunit alpha-1. (3030 aa)
LOC111143738Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
LOC111143852Tropomyosin alpha-4 chain isoform X1; Belongs to the tropomyosin family. (284 aa)
LOC111144160Voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1. (1155 aa)
LOC111143872Troponin C, slow skeletal and cardiac muscles. (161 aa)
LOC111144745LOW QUALITY PROTEIN: ryanodine receptor 2. (5099 aa)
LOC111144193Integrin alpha-6 isoform X1; Belongs to the integrin alpha chain family. (1091 aa)
LOC111143399cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
LOC111145591Tropomyosin beta chain isoform X2; Belongs to the tropomyosin family. (284 aa)
LOC111143787Myosin light chain 3. (197 aa)
LOC111145258Beta-1 adrenergic receptor. (466 aa)
LOC111144138Voltage-dependent calcium channel subunit alpha-2/delta-3. (1091 aa)
LOC111144250Dystroglycan. (891 aa)
LOC111146667Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
LOC111147337Integrin beta; Belongs to the integrin beta chain family. (767 aa)
LOC111147537Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
LOC111145734Actin, cytoplasmic 1. (375 aa)
LOC111147662Laminin subunit alpha-2. (3168 aa)
LOC111148610Sodium/calcium exchanger 3 isoform X4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
LOC111149236Beta-sarcoglycan. (319 aa)
LOC111148592Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
LOC111149549Myosin-binding protein C, cardiac-type. (1272 aa)
LOC111150407Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1984 aa)
LOC111151009Troponin T, cardiac muscle isoform X1. (307 aa)
LOC111151581Alpha-sarcoglycan. (390 aa)
LOC111151764Integrin alpha-3; Belongs to the integrin alpha chain family. (1051 aa)
LOC111153107Tropomyosin alpha-1 chain isoform X1; Belongs to the tropomyosin family. (316 aa)
LOC111153129Integrin alpha-11; Belongs to the integrin alpha chain family. (1230 aa)
LOC111150995Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
LOC111152248Tumor necrosis factor isoform X1; Belongs to the tumor necrosis factor family. (234 aa)
LOC111151068Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LOC111153536Desmin; Belongs to the intermediate filament family. (470 aa)
LOC111154044Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
LOC111151650Voltage-dependent L-type calcium channel subunit beta-1 isoform X1. (607 aa)
LOC111151669LOW QUALITY PROTEIN: titin. (32000 aa)
LOC111155029Integrin beta; Belongs to the integrin beta chain family. (800 aa)
LOC111155043Integrin alpha-V isoform X1; Belongs to the integrin alpha chain family. (1045 aa)
LOC111155265Voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X2. (1110 aa)
LOC111155558Integrin beta; Belongs to the integrin beta chain family. (801 aa)
LOC111155529Integrin alpha-8 isoform X1; Belongs to the integrin alpha chain family. (1062 aa)
LOC111156133Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
LOC111153427Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1093 aa)
LOC111156317Myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform X1. (166 aa)
LOC111155505Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (660 aa)
LOC111157697Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
LOC111157326Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
LOC111157825Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC111157805Voltage-dependent L-type calcium channel subunit beta-3 isoform X1. (484 aa)
LOC111156353Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
LOC111155044Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
LOC111157949Integrin alpha-5 isoform X1; Belongs to the integrin alpha chain family. (1055 aa)
LOC111158126Integrin alpha-IIb isoform X2; Belongs to the integrin alpha chain family. (1037 aa)
LOC111158107Integrin beta; Belongs to the integrin beta chain family. (784 aa)
LOC111157851Integrin beta; Belongs to the integrin beta chain family. (797 aa)
LOC111158430Sodium/calcium exchanger 1 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1004 aa)
LOC111158195Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
LOC111158763Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (942 aa)
LOC111159088Integrin alpha-9 isoform X1; Belongs to the integrin alpha chain family. (1034 aa)
LOC111159692Voltage-dependent calcium channel subunit alpha-2/delta-4. (1121 aa)
LOC111159008Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1013 aa)
LOC111159674Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2191 aa)
LOC111157054Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1138 aa)
LOC111158552Actin, alpha cardiac muscle 1 isoform X1. (377 aa)
LOC111160249Actin, cytoplasmic 2. (375 aa)
LOC111160516Angiotensinogen; Belongs to the serpin family. (477 aa)
LOC111158831Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
LOC111160156Integrin alpha-7 isoform X1; Belongs to the integrin alpha chain family. (1141 aa)
LOC111158197Voltage-dependent calcium channel gamma-5 subunit. (275 aa)
LOC111160727Sodium/calcium exchanger 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
LOC111158207Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
LOC111160262Integrin beta. (1825 aa)
LOC111160297Integrin alpha-4 isoform X1; Belongs to the integrin alpha chain family. (1033 aa)
LOC111162005Integrin alpha-10 isoform X1; Belongs to the integrin alpha chain family. (1165 aa)
LOC111162516cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC111159921Gamma-sarcoglycan isoform X1. (309 aa)
LOC111161420Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
LOC111162323Voltage-dependent calcium channel gamma-3 subunit. (315 aa)
LOC111162403Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1113 aa)
LOC111162286Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1008 aa)
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.