Your Input: | |
| | amn | AMP nucleosidase Amn; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (487 aa) |
| | ade | Adenine deaminase Ade; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (600 aa) |
| | AEI92196.1 | Hypothetical protein; Probably molybdopterin binding. (241 aa) |
| | dapA | Dihydrodipicolinate synthase DapA; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa) |
| | hisD1 | Histidinol dehydrogenase HisD; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (437 aa) |
| | adk2 | Adenylate kinase Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (228 aa) |
| | cpx | Putative purine permease CPE0397. (472 aa) |
| | argE1 | Acetylornithine deacetylase ArgE. (382 aa) |
| | AEI92436.1 | Hypothetical protein. (88 aa) |
| | hisS | histidyl-tRNA synthetase HisS. (533 aa) |
| | hisZ | ATP phosphoribosyltransferase regulatory subunit HisZ. (360 aa) |
| | hisG | ATP-phosphoribosyltransferase HisG; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (230 aa) |
| | AEI92441.1 | Putative vitamin B12-dependent ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (834 aa) |
| | nadK | ATP-NAD kinase-like protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (253 aa) |
| | cdd | Cytidine deaminase Cdd; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (129 aa) |
| | deoA | Thymidine phosphorylase DeoA; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (436 aa) |
| | deoB | Phosphopentomutase DeoB; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (396 aa) |
| | upp | Uracil phosphoribosyltransferase Upp; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (210 aa) |
| | pyrD | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (350 aa) |
| | AEI92507.1 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. (518 aa) |
| | hisD2 | Histidinol dehydrogenase HisD; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (442 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (465 aa) |
| | cmk | Cytidylate kinase Cmk. (205 aa) |
| | trpF | N-(5'-phosphoribosyl)anthranilate isomerase TrpF; Belongs to the TrpF family. (222 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (410 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (263 aa) |
| | aatA | Aspartate aminotransferase aatA. (400 aa) |
| | hisD3 | Histidinol dehydrogenase HisD; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (435 aa) |
| | rbsK | Putative carbohydrate kinase, pfkB family; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (279 aa) |
| | rbsK-2 | Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (300 aa) |
| | AEI92832.1 | Putative chorismate-binding protein. (331 aa) |
| | pyrG | CTP synthase PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (547 aa) |
| | purA | Adenylosuccinate synthetase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (431 aa) |
| | rpiA | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (262 aa) |
| | purD | Phosphoribosylamine--glycine ligase PurD; Belongs to the GARS family. (421 aa) |
| | AEI93054.1 | Dihydroneopterin aldolase-like protein. (307 aa) |
| | folP | Dihydropteroate synthase (DHPS); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (304 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (386 aa) |
| | thrC | Threonine synthase ThrC. (460 aa) |
| | apt | Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (176 aa) |
| | lysC | Aspartokinase LysC; Belongs to the aspartokinase family. (412 aa) |
| | katG | Peroxidase/catalase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (726 aa) |
| | guaA | GMP synthase GuaA; Catalyzes the synthesis of GMP from XMP. (522 aa) |
| | hpt | Hypoxanthine phosphoribosyltransferase Hpt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (181 aa) |
| | AEI93777.1 | Putative competence-damaged protein; Belongs to the CinA family. (155 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (482 aa) |
| | aroQ | 3-dehydroquinate dehydratase AroQ; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (173 aa) |
| | gmk | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. (214 aa) |
| | AEI93912.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase. (456 aa) |
| | hisL | phosphoribosyl-AMP cyclohydrolase HisL; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (128 aa) |
| | purB | Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (434 aa) |
| | hom | Homoserine dehydrogenase Hom. (428 aa) |
| | AEI94070.1 | Putative phosphoribosyltransferase. (206 aa) |
| | AEI94077.1 | Putative cytosine deaminase. (150 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (222 aa) |
| | purS | Phosphoribosylformylglycinamidine (FGAM) synthase PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (76 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Belongs to the SAICAR synthetase family. (253 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (183 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase PurM. (348 aa) |
| | aroB | 3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (370 aa) |
| | aroK | Putative shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (197 aa) |
| | ndk | Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa) |
| | mazG | Protein MazG. (314 aa) |
| | rihA | Pyrimidine-specific ribonucleoside hydrolase RihA. (313 aa) |
| | dcd | Deoxyguanosinetriphosphate triphosphohydrolase-like protein Dcd. (358 aa) |
| | nrdJ | Vitamin B12-dependent ribonucleotide reductase NrdJ; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1214 aa) |
| | gpt | Xanthine phosphoribosyltransferase Gpt; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (176 aa) |
| | trpE | Anthranilate synthase component TrpE; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high conce [...] (503 aa) |
| | trpG | Anthranilate synthase component TrpG. (193 aa) |
| | trpD | Anthranilate phosphoribosyltransferase TrpD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (339 aa) |
| | trpC | Indole-3-glycerol phosphate synthase TrpC; Belongs to the TrpC family. (270 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase ArgC; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (342 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (719 aa) |
| | pyrC | Dihydroorotase PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (344 aa) |
| | pyrE | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (225 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (453 aa) |
| | AEI94433.1 | Putative colicin V production protein. (184 aa) |
| | purF | Amidophosphoribosyltransferase PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (498 aa) |
| | AEI94435.1 | Hypothetical protein. (138 aa) |
| | AEI94436.1 | Putative short chain dehydrogenase. (211 aa) |
| | surE1 | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (261 aa) |
| | pcm | protein-L-isoaspartate O-methyltransferase Pcm; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. (217 aa) |
| | AEI94439.1 | Putative peptidoglycan-binding peptidase. (402 aa) |
| | argE2 | Putative acetylornithine deacetylase ArgE. (387 aa) |
| | pntB | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (498 aa) |
| | pntA | NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. (524 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase HisB. (195 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (212 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase HisA. (239 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (253 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphatase HisE. (105 aa) |
| | cpdA-3 | Calcineurin-like phosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (263 aa) |
| | tmk | Thymidylate kinase Tmk; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (212 aa) |
| | carB | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1119 aa) |
| | tdk | Thymidine kinase Tdk. (193 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (162 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (355 aa) |
| | ribF | Riboflavin biosynthesis protein RibF; Includes riboflavin kinase and FMN adenylyltransferase; Belongs to the ribF family. (310 aa) |
| | AEI94688.1 | Hypothetical protein UPF0260; Belongs to the UPF0260 family. (156 aa) |
| | prs | Ribose-phosphate pyrophosphokinase Prs; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (339 aa) |
| | tyrC | Protein TyrC; Includes arogenate dehydrogenase and prephenate dehydrogenase. (306 aa) |
| | hisC | Histidinol-phosphate aminotransferase HisC; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (361 aa) |
| | pyrB | Aspartate carbamoyltransferase PyrB; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (314 aa) |
| | AEI94748.1 | pyrC': dihydroorotase-like protein. (426 aa) |
| | AEI94765.1 | Putative D-amino acid dehydrogenase, small subunit. (406 aa) |
| | hpd | 4-hydroxyphenylpyruvate dioxygenase Hpd. (364 aa) |
| | AEI94867.1 | Acetyltransferase-like protein. (160 aa) |
| | nusB | N utilization substance protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (160 aa) |
| | ribH1 | 6,7-dimethyl-8-ribityllumazine synthase RibH; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (183 aa) |
| | ribB | Riboflavin biosynthesis protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (374 aa) |
| | ribE | Riboflavin synthase alpha chain. (197 aa) |
| | ribD | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (366 aa) |
| | nrdR | Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (155 aa) |
| | AEI94877.1 | Hypothetical protein UPF0047. (139 aa) |
| | AEI94879.1 | Transcriptional activator HlyU. (94 aa) |
| | AEI94880.1 | Hypothetical protein. (194 aa) |
| | AEI94883.1 | Hypothetical protein. (100 aa) |
| | AEI94922.1 | Hypothetical protein DUF1992. (109 aa) |
| | AEI94924.1 | Putative histidinol-phosphate aminotransferase. (367 aa) |
| | npdA | NAD-dependent deacetylase NpdA; Belongs to the sirtuin family. Class III subfamily. (230 aa) |
| | argF | Ornithine carbamoyltransferase ArgF; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (308 aa) |
| | argD | Class III pyridoxal phosphate dependent aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (391 aa) |
| | deoD | Purine nucleoside phosphorylase deoD-type. (234 aa) |
| | lysA | Diaminopimelate decarboxylase LysA; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa) |
| | argH | Argininosuccinate lyase ArgH. (466 aa) |
| | phnN-2 | Putative thymidine phosphorylase; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (677 aa) |
| | nadC | Nicotinate-nucleotide pyrophosphorylase (carboxylating) NadC; Belongs to the NadC/ModD family. (278 aa) |
| | surE2 | Putative 5'-nucleotidase SurE. (248 aa) |
| | argB | Acetylglutamate kinase ArgB; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (287 aa) |
| | adk1 | Adenylate kinase Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (215 aa) |
| | AEI95369.1 | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. (202 aa) |
| | AEI95412.1 | Putative chorismate mutase type II. (98 aa) |
| | AEI95430.1 | Cytosine deaminase-like protein. (405 aa) |
| | AEI95461.1 | Putative prephenate dehydratase. (285 aa) |
| | AEI95463.1 | NUDIX hydrolase; Belongs to the Nudix hydrolase family. (322 aa) |
| | AEI95464.1 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Belongs to the 5'-nucleotidase family. (598 aa) |
| | nadD | Putative nicotinate (nicotinamide) nucleotide andenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (199 aa) |
| | nadE | Glutamine-dependent NAD(+) synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (552 aa) |
| | pncB | Nicotinate phosphoribosyltransferase PncB; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (430 aa) |
| | pncA | Pyrazinamidase/nicotinamidase PncA. (202 aa) |
| | AEI95626.1 | Rhodanese-like sulfurtransferase; Belongs to the UPF0176 family. (296 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase PyrF. (243 aa) |
| | deoC | Deoxyribose-phosphate aldolase DeoC; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (334 aa) |
| | purH | Bifunctional purine biosynthesis protein PurH; Includes phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase. (528 aa) |
| | dapB | Dihydrodipicolinate reductase DapB; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (272 aa) |
| | AEI95826.1 | Aminotransferase. (393 aa) |
| | ribA | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (362 aa) |
| | dapF | Diaminopimelate epimerase DapF; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (310 aa) |
| | ribH2 | 6,7-dimethyl-8-ribityllumazine synthase RibH; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (148 aa) |
| | aroC | Chorismate synthase AroC; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (366 aa) |
| | aroE | Shikimate 5-dehydrogenase AroE; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (277 aa) |
| | rbsK-3 | pfkB family carbohydrate kinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (290 aa) |
| | argG | Argininosuccinate synthase ArgG; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (406 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (408 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (340 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase DapE; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (381 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase DapD; Belongs to the transferase hexapeptide repeat family. (275 aa) |
