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| | EDM81893.1 | Adenylate or guanylate cyclase; COG0457 FOG: TPR repeat; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (601 aa) |
| | EDM76484.1 | Hypothetical protein; COG1611 Predicted Rossmann fold nucleotide-binding protein. (381 aa) |
| | EDM79330.1 | COG1611 Predicted Rossmann fold nucleotide-binding protein. (179 aa) |
| | EDM79393.1 | Hypothetical protein; COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family. (170 aa) |
| | EDM74009.1 | Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (653 aa) |
| | cysD | Sulfate adenylyltransferase, small subunit; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes. (301 aa) |
| | EDM78888.1 | Hypothetical protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. (106 aa) |
| | EDM79212.1 | Hypothetical protein; COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). (481 aa) |
| | cysC | Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. (192 aa) |
| | EDM79244.1 | Hypothetical protein; COG0563 Adenylate kinase and related kinases. (173 aa) |
| | EDM79259.1 | COG1816 Adenosine deaminase. (365 aa) |
| | EDM79260.1 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (479 aa) |
| | EDM79290.1 | COG0515 Serine/threonine protein kinase. (1315 aa) |
| | EDM76827.1 | COG1253 Hemolysins and related proteins containing CBS domains. (436 aa) |
| | EDM81736.1 | Hypothetical protein; COG1409 Predicted phosphohydrolases. (367 aa) |
| | EDM81749.1 | LysM domain protein; COG1652 Uncharacterized protein containing LysM domain. (471 aa) |
| | EDM81769.1 | COG0628 Predicted permease. (451 aa) |
| | EDM81797.1 | Putative ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (356 aa) |
| | EDM81798.1 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa) |
| | EDM81896.1 | CBS domain containing membrane protein; COG0517 FOG: CBS domain. (138 aa) |
| | EDM81905.1 | Thermonuclease family protein; COG1525 Micrococcal nuclease (thermonuclease) homologs. (168 aa) |
| | EDM81907.1 | Nuclease (SNase-like) protein; COG1525 Micrococcal nuclease (thermonuclease) homologs. (455 aa) |
| | EDM81952.1 | COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). (725 aa) |
| | EDM76047.1 | Hypothetical protein; COG4252 Predicted transmembrane sensor domain. (705 aa) |
| | EDM78946.1 | HIT-family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. (141 aa) |
| | EDM79001.1 | Hypothetical protein; COG0302 GTP cyclohydrolase I. (431 aa) |
| | EDM79010.1 | Hypothetical protein; COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases. (178 aa) |
| | EDM76362.1 | Carbohydrate kinase, PfkB family protein; COG0524 Sugar kinases, ribokinase family. (305 aa) |
| | EDM76296.1 | Metallophosphoesterase; COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases. (357 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (360 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (157 aa) |
| | EDM78250.1 | Hypothetical protein; COG0563 Adenylate kinase and related kinases. (186 aa) |
| | rph-2 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (248 aa) |
| | EDM74303.1 | Hypothetical protein; COG0127 Xanthosine triphosphate pyrophosphatase. (232 aa) |
| | tilS | Helix-turn-helix, Fis-type; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (362 aa) |
| | EDM77534.1 | Hypothetical protein; COG1413 FOG: HEAT repeat. (712 aa) |
| | nrdR | Hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes. (235 aa) |
| | EDM77385.1 | DNA-binding protein HU; COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family. (241 aa) |
| | purC-2 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. (323 aa) |
| | purF | Amidophosphoribosyl transferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (485 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (214 aa) |
| | EDM74085.1 | GTP pyrophosphokinase; COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases. (852 aa) |
| | EDM79054.1 | Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (94 aa) |
| | EDM79057.1 | Stationary-phase survival protein SurE; COG0496 Predicted acid phosphatase. (218 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (191 aa) |
| | EDM79075.1 | Putative cell division protein BolA; COG0271 Stress-induced morphogen (activity unknown); Belongs to the BolA/IbaG family. (106 aa) |
| | EDM79091.1 | Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (210 aa) |
| | EDM79101.1 | MazG family protein; COG1694 Predicted pyrophosphatase. (304 aa) |
| | purM | Putative phosphoribosylformylglycinamidine cyclo-ligase; COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. (357 aa) |
| | EDM79109.1 | COG0515 Serine/threonine protein kinase. (1324 aa) |
| | EDM80363.1 | Magnesium (Mg2+) transporter-like protein; Acts as a magnesium transporter. (451 aa) |
| | guaA | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. (520 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (493 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (202 aa) |
| | EDM78743.1 | Hypothetical protein; COG0628 Predicted permease. (482 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa) |
| | EDM73801.1 | COG2343 Uncharacterized protein conserved in bacteria. (186 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (427 aa) |
| | purD | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. (423 aa) |
| | purH | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). (543 aa) |
| | EDM80802.1 | Metallophosphoesterase; COG1409 Predicted phosphohydrolases. (292 aa) |
| | EDM77663.1 | Protein kinase; COG0515 Serine/threonine protein kinase. (1147 aa) |
| | EDM74819.1 | Putative dehydrogenase; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. (920 aa) |
| | EDM74820.1 | Putative aldehyde or xanthine dehydrogenase, molybdopterin binding subunit protein; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs. (355 aa) |
| | EDM75445.1 | Hypothetical protein; COG1413 FOG: HEAT repeat. (318 aa) |
| | EDM78541.1 | Hypothetical protein; COG0617 tRNA nucleotidyltransferase/poly(A) polymerase. (443 aa) |
| | EDM78542.1 | Hypothetical protein. (213 aa) |
| | EDM74753.1 | COG0515 Serine/threonine protein kinase. (802 aa) |
| | EDM74760.1 | COG0549 Carbamate kinase; Belongs to the carbamate kinase family. (319 aa) |
| | EDM75671.1 | Adenylate cyclase; COG0840 Methyl-accepting chemotaxis protein. (587 aa) |
| | EDM79657.1 | COG2351 Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (117 aa) |
| | EDM79690.1 | COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain. (303 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (1010 aa) |
| | EDM75769.1 | COG0515 Serine/threonine protein kinase. (1318 aa) |
| | EDM74057.1 | Hypothetical protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. (173 aa) |
| | EDM75252.1 | Hypothetical protein; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. (178 aa) |
| | EDM75253.1 | Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding protein; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. (816 aa) |
| | EDM75254.1 | Molybdopterin dehydrogenase, FAD-binding protein; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs. (338 aa) |
| | EDM76329.1 | Putative serine/threonine-protein kinase; COG0515 Serine/threonine protein kinase. (1238 aa) |
| | EDM76771.1 | Phage tail assembly-like protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. (207 aa) |
| | EDM75960.1 | COG0402 Cytosine deaminase and related metal-dependent hydrolases. (407 aa) |
| | EDM80078.1 | Hypothetical protein. (395 aa) |
| | EDM74923.1 | COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (207 aa) |
| | EDM79532.1 | Hypothetical protein. (333 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (285 aa) |
| | EDM79948.1 | COG2086 Electron transfer flavoprotein, beta subunit. (269 aa) |
| | EDM79971.1 | COG0515 Serine/threonine protein kinase. (606 aa) |
| | EDM76544.1 | COG2343 Uncharacterized protein conserved in bacteria. (93 aa) |
| | EDM78033.1 | Probable acid sphingomyelinase-like phosphodiesterase transmembrane protein. (546 aa) |
| | ttcA | ATPase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (310 aa) |
| | EDM78039.1 | COG4339 Uncharacterized protein conserved in bacteria. (212 aa) |
| | EDM78040.1 | Hypothetical protein; COG1957 Inosine-uridine nucleoside N-ribohydrolase. (286 aa) |
| | EDM78049.1 | Hypothetical protein; COG4639 Predicted kinase. (140 aa) |
| | EDM78052.1 | Putative oxidoreductase; COG2072 Predicted flavoprotein involved in K+ transport. (467 aa) |
| | EDM78053.1 | COG0044 Dihydroorotase and related cyclic amidohydrolases. (438 aa) |
| | alc | COG4266 Allantoicase; Belongs to the allantoicase family. (338 aa) |
| | EDM78055.1 | COG3195 Uncharacterized protein conserved in bacteria. (174 aa) |
| | EDM78056.1 | COG2351 Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (114 aa) |
| | EDM75908.1 | Anti-sigma-factor antagonist (STAS) domain protein; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (328 aa) |
| | EDM80956.1 | COG1652 Uncharacterized protein containing LysM domain. (259 aa) |
| | EDM81058.1 | Putative amino transferase; COG0518 GMP synthase - Glutamine amidotransferase domain. (245 aa) |
| | EDM75219.1 | COG0005 Purine nucleoside phosphorylase. (278 aa) |
| | EDM75227.1 | Phosphatase, Ppx/GppA family protein; COG0248 Exopolyphosphatase. (297 aa) |
| | ttcA-2 | PP-loop; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (287 aa) |
| | EDM79169.1 | Hypothetical protein; COG2102 Predicted ATPases of PP-loop superfamily. (215 aa) |
| | adk-2 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (176 aa) |
| | EDM74586.1 | Putative transcriptional regulator, XRE family protein; COG0517 FOG: CBS domain. (137 aa) |
| | EDM75581.1 | COG0726 Predicted xylanase/chitin deacetylase. (292 aa) |
| | EDM78612.1 | NUDIX hydrolase family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (216 aa) |
| | EDM81209.1 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (195 aa) |
| | EDM75132.1 | Bis(5'-nucleosyl)-tetraphosphatase; COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases. (245 aa) |
| | EDM74838.1 | Hypothetical protein; COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases. (258 aa) |
| | EDM75489.1 | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (741 aa) |
| | EDM75519.1 | SREBP protease/CBS domain; COG1994 Zn-dependent proteases. (272 aa) |
| | EDM79797.1 | Hypothetical protein. (369 aa) |
| | EDM79815.1 | Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1239 aa) |
| | EDM79850.1 | Polysaccharide deacetylase domain protein; COG0726 Predicted xylanase/chitin deacetylase. (317 aa) |
| | EDM78786.1 | COG3205 Predicted membrane protein. (74 aa) |
| | EDM78452.1 | Hypothetical protein. (137 aa) |
| | EDM75856.1 | Hypothetical protein; COG0457 FOG: TPR repeat. (522 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (322 aa) |
| | EDM76729.1 | COG0515 Serine/threonine protein kinase. (1082 aa) |
| | EDM74350.1 | Putative lipoprotein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. (618 aa) |
| | EDM75106.1 | Putative adenylate cyclase; COG1716 FOG: FHA domain. (548 aa) |
| | EDM78106.1 | Sensor histidine kinase; COG3899 Predicted ATPase. (1478 aa) |
| | ychF | Translation-associated GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (366 aa) |
| | EDM78132.1 | DNA-binding protein HU; COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family. (128 aa) |
| | EDM80114.1 | Putative adenylate cyclase; COG1716 FOG: FHA domain. (529 aa) |
| | EDM80597.1 | Hypothetical protein. (196 aa) |
| | EDM80634.1 | Hypothetical protein. (118 aa) |
| | EDM76904.1 | ATP-binding region, ATPase domain protein; COG3899 Predicted ATPase. (1485 aa) |
| | EDM77429.1 | Predicted ATPase; COG0515 Serine/threonine protein kinase. (1204 aa) |
| | EDM75070.1 | Probable endonuclease. (285 aa) |
| | EDM81394.1 | COG1816 Adenosine deaminase. (358 aa) |
| | EDM81404.1 | COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). (410 aa) |
| | EDM81411.1 | Hypothetical protein. (291 aa) |
| | EDM81478.1 | HAD superfamily (subfamily IG) hydrolase, 5'-Nucleotidase. (516 aa) |
| | EDM81236.1 | COG0518 GMP synthase - Glutamine amidotransferase domain. (220 aa) |
| | EDM81241.1 | Similar to the Icc protein; COG1409 Predicted phosphohydrolases. (229 aa) |
| | EDM81281.1 | COG4630 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A. (512 aa) |
| | EDM81282.1 | COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B. (798 aa) |
| | EDM81356.1 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (485 aa) |
| | EDM74714.1 | Hypothetical protein; COG1525 Micrococcal nuclease (thermonuclease) homologs. (330 aa) |
| | EDM75207.1 | Hypothetical protein; COG0708 Exonuclease III. (343 aa) |
| | EDM80482.1 | Helicase, DEAD/DEAH family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. (128 aa) |
| | EDM80515.1 | 2Fe-2S ferredoxin; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. (255 aa) |
| | EDM80516.1 | Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding protein; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. (784 aa) |
| | EDM80517.1 | Molybdopterin dehydrogenase, FAD-binding protein; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs. (355 aa) |
| | EDM80538.1 | COG0402 Cytosine deaminase and related metal-dependent hydrolases. (860 aa) |
| | EDM80540.1 | Hypothetical protein; COG2374 Predicted extracellular nuclease. (474 aa) |
| | EDM80541.1 | Thermonuclease family protein; COG1525 Micrococcal nuclease (thermonuclease) homologs. (182 aa) |
| | EDM76253.1 | Molybdopterin dehydrogenase, FAD-binding protein; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs. (325 aa) |
| | EDM76254.1 | COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. (875 aa) |
