STRINGSTRING
AGI65825.1 AGI65825.1 leuC2 leuC2 leuD2 leuD2 leuB leuB ilvD3 ilvD3 AGI66285.1 AGI66285.1 leuA leuA ilvC ilvC AGI67885.1 AGI67885.1 ilvD1 ilvD1 ilvI ilvI AGI68353.1 AGI68353.1 leuD3 leuD3 leuC1 leuC1 leuD1 leuD1 leuC3 leuC3 ilvE ilvE
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
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Your Input:
AGI65825.1Putative dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (599 aa)
leuC23-isopropylmalate dehydratase LeuC; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (468 aa)
leuD23-isopropylmalate dehydratase small subunit LeuD; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa)
leuBIsopropylmalate dehydrogenase LeuB; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (367 aa)
ilvD3Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (577 aa)
AGI66285.1Thiamine pyrophosphate binding enzyme; Acetolactate synthase large subunit-like; Belongs to the TPP enzyme family. (551 aa)
leuA2-isopropylmalate synthase LeuA; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (519 aa)
ilvCKetol-acid reductoisomerase IlvC; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (340 aa)
AGI67885.1alpha-IPM synthetase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (545 aa)
ilvD1Dihydroxy-acid dehydratase IlvD; Alternative name(s): DAD; Belongs to the IlvD/Edd family. (622 aa)
ilvIAcetolactate synthase isozyme 3 large subunit IlvI. (585 aa)
AGI68353.1Putative acetolactate synthase isozyme 3 small subunit. (187 aa)
leuD33-isopropylmalate dehydratase small subunit LeuD. (177 aa)
leuC13-isopropylmalate dehydratase large subunit LeuC. (425 aa)
leuD13-isopropylmalate dehydratase LeuD; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (196 aa)
leuC33-isopropylmalate dehydratase LeuC; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (465 aa)
ilvEBranched-chain-amino-acid aminotransferase IlvE; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (289 aa)
Your Current Organism:
Octadecabacter antarcticus
NCBI taxonomy Id: 391626
Other names: O. antarcticus 307, Octadecabacter antarcticus 307, Octadecabacter antarcticus CIP 106731, Octadecabacter antarcticus str. 307, Octadecabacter antarcticus strain 307, unidentified alpha proteobacterium (clone 307), unidentified alpha proteobacterium clone 307
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