STRINGSTRING
Veis_4509 Veis_4509 Veis_3999 Veis_3999 Veis_3540 Veis_3540 Veis_3404 Veis_3404 ilvD ilvD Veis_2663 Veis_2663 Veis_2516 Veis_2516 ilvE ilvE Veis_0037 Veis_0037 ilvA ilvA Veis_0339 Veis_0339 Veis_0534 Veis_0534 Veis_0740 Veis_0740 Veis_0789 Veis_0789 Veis_0790 Veis_0790 Veis_0940 Veis_0940 Veis_1745 Veis_1745 Veis_1746 Veis_1746 ilvC ilvC Veis_1933 Veis_1933 Veis_2151 Veis_2151 Veis_4911 Veis_4911 Veis_4872 Veis_4872 Veis_4523 Veis_4523 Veis_4212 Veis_4212
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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Your Input:
Veis_4509PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hma:rrnB0209 acetolactate synthase large subunit. (560 aa)
Veis_3999PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: rha:RHA1_ro03582 sulfoacetaldehyde acetyltransferase; Belongs to the TPP enzyme family. (605 aa)
Veis_3540Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: mlo:mll7192 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (569 aa)
Veis_3404Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: pol:Bpro_2297 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (576 aa)
ilvDKEGG: pol:Bpro_2052 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (568 aa)
Veis_2663PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: rfr:Rfer_1912 homoserine dehydrogenase. (444 aa)
Veis_2516KEGG: rsp:RSP_3155 thiamine pyrophosphate-requiring enzyme. (56 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (313 aa)
Veis_0037Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: pol:Bpro_3810 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (629 aa)
ilvAL-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (565 aa)
Veis_0339PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: bur:Bcep18194_C6721 acetolactate synthase, large subunit. (576 aa)
Veis_0534PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: bam:Bamb_3882 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (321 aa)
Veis_0740L-arabinonate dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: bam:Bamb_4925 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (577 aa)
Veis_0789Acetolactate synthase, large subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: rfr:Rfer_0882 thiamine pyrophosphate enzyme-like TPP-binding; Belongs to the TPP enzyme family. (564 aa)
Veis_0790Acetolactate synthase, large subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: reh:H16_B0313 acetolactate synthase large subunit (TPP dependent). (564 aa)
Veis_0940D-xylonate dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: ccr:CC0819 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (592 aa)
Veis_1745TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: pol:Bpro_2317 acetolactate synthase, large subunit, biosynthetic type. (593 aa)
Veis_1746TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pol:Bpro_2318 acetolactate synthase, small subunit. (163 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (347 aa)
Veis_1933PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: rme:Rmet_3896 thiamine pyrophosphate enzyme-like TPP-binding. (513 aa)
Veis_2151L-threonine ammonia-lyase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: bch:Bcen2424_6169 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (319 aa)
Veis_4911Threonine ammonia-lyase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: pau:PA14_53260 hypothetical protein. (323 aa)
Veis_4872KEGG: pol:Bpro_3612 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. (379 aa)
Veis_4523Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: pol:Bpro_5111 dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (562 aa)
Veis_4212PFAM: thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: rxy:Rxyl_2271 thiamine pyrophosphate enzyme-like TPP binding region. (477 aa)
Your Current Organism:
Verminephrobacter eiseniae
NCBI taxonomy Id: 391735
Other names: V. eiseniae EF01-2, Verminephrobacter eiseniae EF01-2, Verminephrobacter eiseniae str. EF01-2, Verminephrobacter eiseniae strain EF01-2
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