STRINGSTRING
Veis_1965 Veis_1965 Veis_4927 Veis_4927 Veis_4911 Veis_4911 Veis_4774 Veis_4774 lysA lysA Veis_4721 Veis_4721 Veis_4679 Veis_4679 Veis_4530 Veis_4530 Veis_4529 Veis_4529 Veis_4509 Veis_4509 Veis_4437 Veis_4437 Veis_4383 Veis_4383 hisC hisC alr alr Veis_4287 Veis_4287 glyA glyA Veis_4212 Veis_4212 Veis_4134 Veis_4134 Veis_4123 Veis_4123 Veis_3999 Veis_3999 Veis_3979 Veis_3979 Veis_3780 Veis_3780 Veis_3477 Veis_3477 Veis_3409 Veis_3409 Veis_3398 Veis_3398 Veis_3297 Veis_3297 dxs dxs acpP acpP Veis_3196 Veis_3196 Veis_3136 Veis_3136 serC serC Veis_3084 Veis_3084 hemL hemL Veis_2990 Veis_2990 Veis_2945 Veis_2945 Veis_2902 Veis_2902 Veis_2819 Veis_2819 Veis_2662 Veis_2662 Veis_2516 Veis_2516 Veis_2435 Veis_2435 iscS iscS Veis_2370 Veis_2370 Veis_2152 Veis_2152 Veis_2151 Veis_2151 Veis_2145 Veis_2145 Veis_2000 Veis_2000 Veis_1933 Veis_1933 argD argD Veis_1762 Veis_1762 Veis_1745 Veis_1745 Veis_1705 Veis_1705 Veis_1687 Veis_1687 Veis_1588 Veis_1588 Veis_1286 Veis_1286 Veis_1249 Veis_1249 Veis_1234 Veis_1234 Veis_0863 Veis_0863 Veis_0824 Veis_0824 Veis_0790 Veis_0790 Veis_0789 Veis_0789 Veis_0659 Veis_0659 Veis_0534 Veis_0534 Veis_0465 Veis_0465 Veis_0362 Veis_0362 Veis_0339 Veis_0339 ilvA ilvA Veis_0274 Veis_0274 Veis_0265 Veis_0265 Veis_0066 Veis_0066 Veis_0044 Veis_0044 Veis_0014 Veis_0014
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Veis_1965Indolepyruvate ferredoxin oxidoreductase; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: pol:Bpro_4734 thiamine pyrophosphate enzyme-like TPP-binding. (737 aa)
Veis_4927PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_2403 aminotransferase, class I and II. (393 aa)
Veis_4911Threonine ammonia-lyase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: pau:PA14_53260 hypothetical protein. (323 aa)
Veis_4774PFAM: periplasmic binding protein; KEGG: pol:Bpro_2782 periplasmic binding protein. (311 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (414 aa)
Veis_4721Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: sil:SPOA0379 transcriptional regulator, GntR family. (492 aa)
Veis_4679Aminotransferase; KEGG: dar:Daro_1233 histidinol-phosphate aminotransferase. (60 aa)
Veis_4530Hypothetical protein. (125 aa)
Veis_4529PFAM: Pyridoxal-dependent decarboxylase; KEGG: sus:Acid_7941 pyridoxal-dependent decarboxylase. (350 aa)
Veis_4509PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hma:rrnB0209 acetolactate synthase large subunit. (560 aa)
Veis_4437PFAM: aminotransferase class-III; KEGG: pol:Bpro_4286 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
Veis_4383KEGG: ana:alr2678 probable acyl-CoA synthase. (96 aa)
hisCAminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II; KEGG: rfr:Rfer_2947 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (396 aa)
alrAlanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (371 aa)
Veis_4287PFAM: regulatory protein GntR, HTH; KEGG: reh:H16_B1891 transcriptional regulator, MocR family. (512 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (438 aa)
Veis_4212PFAM: thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: rxy:Rxyl_2271 thiamine pyrophosphate enzyme-like TPP binding region. (477 aa)
Veis_4134KEGG: bbr:BB1542 cystathionase beta-lyase; TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. (400 aa)
Veis_4123PFAM: aminotransferase class-III; KEGG: bja:blr3552 putative glutamate-1-semialdehyde 2,1-aminomutase. (234 aa)
Veis_3999PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: rha:RHA1_ro03582 sulfoacetaldehyde acetyltransferase; Belongs to the TPP enzyme family. (605 aa)
Veis_3979KEGG: pol:Bpro_2624 2-oxoglutarate dehydrogenase, E1 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; Transketolase, central region. (959 aa)
Veis_3780KEGG: rfr:Rfer_3160 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. (436 aa)
Veis_3477KEGG: bxe:Bxe_C1131 cystathionine beta-lyase; TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase. (393 aa)
Veis_3409Cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: rfr:Rfer_2294 Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. (426 aa)
Veis_3398KEGG: rfr:Rfer_2805 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. (731 aa)
Veis_3297PFAM: aminotransferase, class V; KEGG: reu:Reut_B5541 aminotransferase, class V. (393 aa)
dxs1-Deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (631 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (79 aa)
Veis_3196PFAM: aminotransferase class-III; KEGG: pol:Bpro_0421 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (458 aa)
Veis_3136PFAM: aminotransferase class-III; KEGG: bam:Bamb_4163 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (456 aa)
serCAminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (381 aa)
Veis_3084PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: pol:Bpro_3048 2OG-Fe(II) oxygenase. (227 aa)
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: rfr:Rfer_1369 glutamate-1-semialdehyde-2,1-aminomutase. (437 aa)
Veis_2990PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: plu:plu4674 hypothetical protein. (401 aa)
Veis_2945PFAM: aminotransferase, class V; KEGG: bld:BLi03531 YcbU. (381 aa)
Veis_2902PFAM: aminotransferase, class I and II; KEGG: bbr:BB3570 putative aspartate aminotransferase. (406 aa)
Veis_2819PFAM: aminotransferase, class V; aminotransferase, class I and II; KEGG: pol:Bpro_3262 aminotransferase, class I and II. (385 aa)
Veis_2662PFAM: aminotransferase, class I and II; KEGG: rfr:Rfer_1911 aminotransferase, class I and II. (409 aa)
Veis_2516KEGG: rsp:RSP_3155 thiamine pyrophosphate-requiring enzyme. (56 aa)
Veis_2435PFAM: beta-ketoacyl synthase; Thioesterase; acyl transferase domain protein; condensation domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Methyltransferase type 11; Methyltransferase type 12; Non-ribosomal peptide synthetase; KR; KEGG: psp:PSPPH_2899 yersiniabactin polyketide/non-ribosomal peptide synthetase. (3275 aa)
iscSCysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (406 aa)
Veis_2370PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_2175 aspartate transaminase. (401 aa)
Veis_2152Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: bxe:Bxe_C0055 transcriptional regulator, GntR. (465 aa)
Veis_2151L-threonine ammonia-lyase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: bch:Bcen2424_6169 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (319 aa)
Veis_2145PFAM: aminotransferase class-III; KEGG: bxe:Bxe_C0061 putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (465 aa)
Veis_2000Hypothetical protein; KEGG: bxe:Bxe_C0664 putative pyruvate decarboxylase. (167 aa)
Veis_1933PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: rme:Rmet_3896 thiamine pyrophosphate enzyme-like TPP-binding. (513 aa)
argDTIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class-III; KEGG: pol:Bpro_3572 acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (400 aa)
Veis_1762Putative transcriptional regulator, GntR family; PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_2746 aminotransferase, class I and II. (396 aa)
Veis_1745TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: pol:Bpro_2317 acetolactate synthase, large subunit, biosynthetic type. (593 aa)
Veis_1705PFAM: aminotransferase class-III; KEGG: pol:Bpro_2003 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (447 aa)
Veis_1687Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (239 aa)
Veis_1588Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: pfl:PFL_2191 transcriptional regulator, GntR family. (485 aa)
Veis_1286Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (470 aa)
Veis_1249PFAM: aminotransferase class-III; KEGG: ace:Acel_1287 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (456 aa)
Veis_1234Aminotransferase; KEGG: pol:Bpro_0900 adenosylmethionine-8-amino-7-oxononanoate aminotransferase. (102 aa)
Veis_0863KEGG: bpe:BP3435 hypothetical protein. (363 aa)
Veis_0824PFAM: aminotransferase class-III; KEGG: rfr:Rfer_0351 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (465 aa)
Veis_0790Acetolactate synthase, large subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: reh:H16_B0313 acetolactate synthase large subunit (TPP dependent). (564 aa)
Veis_0789Acetolactate synthase, large subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: rfr:Rfer_0882 thiamine pyrophosphate enzyme-like TPP-binding; Belongs to the TPP enzyme family. (564 aa)
Veis_0659PFAM: aminotransferase class-III; KEGG: mlo:mlr6714 ornithine-oxo-acid transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (428 aa)
Veis_0534PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: bam:Bamb_3882 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (321 aa)
Veis_0465PFAM: MOSC domain containing protein; MOSC domain protein beta barrel domain protein; KEGG: pol:Bpro_1126 MOSC-like beta barrel. (290 aa)
Veis_0362Putative transcriptional regulator, GntR family; PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_4240 aminotransferase, class I and II. (426 aa)
Veis_0339PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: bur:Bcep18194_C6721 acetolactate synthase, large subunit. (576 aa)
ilvAL-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (565 aa)
Veis_0274PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_1997 aminotransferase, class I and II. (409 aa)
Veis_0265Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: bam:Bamb_6437 cystathionine gamma-synthase. (423 aa)
Veis_0066PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: bur:Bcep18194_A4566 acetolactate synthase. (627 aa)
Veis_0044Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: mlo:mll2434 probable transcriptional regulator. (493 aa)
Veis_0014Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (911 aa)
Your Current Organism:
Verminephrobacter eiseniae
NCBI taxonomy Id: 391735
Other names: V. eiseniae EF01-2, Verminephrobacter eiseniae EF01-2, Verminephrobacter eiseniae str. EF01-2, Verminephrobacter eiseniae strain EF01-2
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.