Your Input: | |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: pol:Bpro_2678 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1089 aa) |
| | carA | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: rfr:Rfer_2004 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (387 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (296 aa) |
| | Veis_1207 | Cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: psb:Psyr_2745 pyridoxal-5'-phosphate-dependent enzyme, beta subunit:ornithine cyclodeaminase/mu-crystallin. (322 aa) |
| | trpC | PFAM: Indole-3-glycerol phosphate synthase; KEGG: pol:Bpro_4451 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (267 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (346 aa) |
| | trpE | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] (517 aa) |
| | argB | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (296 aa) |
| | Veis_1286 | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (470 aa) |
| | Veis_1349 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: bja:blr2741 3-isopropylmalate dehydrogenase. (356 aa) |
| | argH | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: rfr:Rfer_1710 argininosuccinate lyase. (488 aa) |
| | selD | Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP. (361 aa) |
| | Veis_1745 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: pol:Bpro_2317 acetolactate synthase, large subunit, biosynthetic type. (593 aa) |
| | Veis_1746 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pol:Bpro_2318 acetolactate synthase, small subunit. (163 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (347 aa) |
| | thrB | KEGG: rfr:Rfer_1323 homoserine kinase; TIGRFAM: homoserine kinase; PFAM: aminoglycoside phosphotransferase; Belongs to the pseudomonas-type ThrB family. (316 aa) |
| | Veis_3121 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: pol:Bpro_1792 chorismate mutase. (365 aa) |
| | argD | TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class-III; KEGG: pol:Bpro_3572 acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (400 aa) |
| | arcB | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (306 aa) |
| | Veis_1910 | KEGG: bbr:BB4085 putative 3-isopropylmalate dehydratase large subunit; TIGRFAM: homoaconitate hydratase family protein; PFAM: aconitate hydratase domain protein. (428 aa) |
| | Veis_1911 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: bbr:BB4086 putative 3-isopropylmalate dehydratase small subunit; Belongs to the LeuD family. (172 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (299 aa) |
| | Veis_1933 | PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: rme:Rmet_3896 thiamine pyrophosphate enzyme-like TPP-binding. (513 aa) |
| | Veis_1958 | KEGG: mfa:Mfla_0459 ferredoxin-dependent glutamate synthase. (113 aa) |
| | argH-2 | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: bam:Bamb_6457 argininosuccinate lyase. (480 aa) |
| | Veis_2136 | KEGG: pol:Bpro_4215 phenylalanine-4-hydroxylase, monomeric form; TIGRFAM: phenylalanine-4-hydroxylase; PFAM: aromatic amino acid hydroxylase. (275 aa) |
| | Veis_2151 | L-threonine ammonia-lyase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: bch:Bcen2424_6169 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (319 aa) |
| | Veis_2233 | KEGG: reu:Reut_A1775 argininosuccinate lyase. (208 aa) |
| | Veis_2293 | PFAM: glycosyl transferase, family 3; KEGG: pol:Bpro_3280 glycosyl transferase, family 3. (307 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (282 aa) |
| | Veis_2368 | PFAM: dihydrodipicolinate synthetase; KEGG: reh:H16_B1831 dihydrodipicolinate synthase (DapA); Belongs to the DapA family. (301 aa) |
| | trpF | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: pol:Bpro_3615 phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (256 aa) |
| | trpB | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (421 aa) |
| | trpA | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (279 aa) |
| | Veis_2395 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rfr:Rfer_2933 glutamate synthase (ferredoxin). (1586 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (313 aa) |
| | Veis_2516 | KEGG: rsp:RSP_3155 thiamine pyrophosphate-requiring enzyme. (56 aa) |
| | Veis_2663 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: rfr:Rfer_1912 homoserine dehydrogenase. (444 aa) |
| | Veis_2664 | KEGG: rfr:Rfer_1913 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (516 aa) |
| | Veis_2698 | KEGG: pol:Bpro_3066 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. (364 aa) |
| | Veis_4847 | TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase; KEGG: rfr:Rfer_0669 asparagine synthase, glutamine-hydrolyzing. (584 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (414 aa) |
| | Veis_4686 | Dihydrodipicolinate synthetase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (298 aa) |
| | leuD-2 | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa) |
| | leuC-2 | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (468 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (382 aa) |
| | Veis_4523 | Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: pol:Bpro_5111 dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (562 aa) |
| | Veis_4509 | PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hma:rrnB0209 acetolactate synthase large subunit. (560 aa) |
| | metE | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (789 aa) |
| | Veis_4442 | Delta-1-pyrroline-5-carboxylate dehydrogenase / L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1310 aa) |
| | Veis_4426 | Methylthioadenosine nucleosidase; PFAM: purine and other phosphorylases, family 1; KEGG: ccr:CC2266 5'-methylthioadenosine nucleosidase / S-adenosylhomocysteine nucleosidase. (323 aa) |
| | Veis_4390 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: pol:Bpro_1422 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. (413 aa) |
| | Veis_4358 | Aconitase; PFAM: aconitate hydratase domain protein; aconitate hydratase 2; KEGG: rso:RSp0332 probable aconitate hydratase 2 transmembrane protein; Belongs to the aconitase/IPM isomerase family. (863 aa) |
| | alr | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (371 aa) |
| | Veis_4335 | PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; KEGG: bxe:Bxe_B0922 putative nitrite/sulfite reductase. (593 aa) |
| | Veis_4333 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. (293 aa) |
| | Veis_4258 | TIGRFAM: serine O-acetyltransferase; KEGG: pol:Bpro_3291 serine O-acetyltransferase. (260 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (438 aa) |
| | Veis_4214 | Gentisate 1,2-dioxygenase; PFAM: Cupin 2, conserved barrel domain protein; KEGG: rso:RSc1825 putative dioxygenase oxidoreductase protein. (387 aa) |
| | Veis_4212 | PFAM: thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: rxy:Rxyl_2271 thiamine pyrophosphate enzyme-like TPP binding region. (477 aa) |
| | Veis_4113 | PFAM: dihydrodipicolinate synthetase; KEGG: eca:ECA1002 putative dihydrodipicolinate synthase; Belongs to the DapA family. (311 aa) |
| | Veis_3999 | PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: rha:RHA1_ro03582 sulfoacetaldehyde acetyltransferase; Belongs to the TPP enzyme family. (605 aa) |
| | argJ | Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (425 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (380 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (438 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (512 aa) |
| | Veis_3580 | PFAM: protein of unknown function DUF993; KEGG: sme:SMc04402 hypothetical protein. (394 aa) |
| | Veis_3541 | PFAM: dihydrodipicolinate synthetase; KEGG: rha:RHA1_ro05285 probable dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. (303 aa) |
| | Veis_2707 | 2-dehydro-3-deoxy-L-arabinonate dehydratase; PFAM: dihydrodipicolinate synthetase; KEGG: pol:Bpro_2837 dihydrodipicolinate synthetase; Belongs to the DapA family. (316 aa) |
| | argC-2 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (326 aa) |
| | Veis_2739 | PFAM: dihydrodipicolinate synthetase; KEGG: lxx:Lxx10270 dihydrodipicolinate synthase; Belongs to the DapA family. (312 aa) |
| | Veis_2871 | PFAM: aminoglycoside phosphotransferase; KEGG: sal:Sala_1765 aminoglycoside phosphotransferase. (358 aa) |
| | Veis_3031 | Ferredoxin-dependent glutamate synthase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; dihydroorotate dehydrogenase; ferredoxin-dependent glutamate synthase; KEGG: reh:H16_B2194 glutamate synthase [NADPH], glutamate synthase amidotransferase domain; Belongs to the glutamate synthase family. (446 aa) |
| | Veis_3032 | PFAM: glutamate synthase, alpha subunit domain protein; KEGG: reh:H16_B2193 glutamine amidotransferases class-II. (228 aa) |
| | Veis_3034 | PFAM: glutamine synthetase, catalytic region; KEGG: reh:H16_B2191 glutamine synthetase. (463 aa) |
| | serC | Aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (381 aa) |
| | Veis_3540 | Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: mlo:mll7192 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (569 aa) |
| | Veis_3461 | PFAM: argininosuccinate synthase; KEGG: rso:RSc2553 probable argininosuccinate synthase protein; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (453 aa) |
| | Veis_3404 | Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: pol:Bpro_2297 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (576 aa) |
| | Veis_3266 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: rfr:Rfer_1520 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (362 aa) |
| | ilvD | KEGG: pol:Bpro_2052 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (568 aa) |
| | Veis_3186 | KEGG: rso:RSp0996 probable tartrate dehydrogenase oxidoreductase protein; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. (362 aa) |
| | Veis_3173 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (162 aa) |
| | Veis_3156 | KEGG: rfr:Rfer_2977 putative transmembrane protein. (271 aa) |
| | Veis_3154 | KEGG: pol:Bpro_1807 glutamine synthetase, type I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp. (471 aa) |
| | Veis_3122 | PFAM: Prephenate dehydrogenase; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: rfr:Rfer_1568 prephenate dehydrogenase. (300 aa) |
| | Veis_4940 | KEGG: rfr:Rfer_1353 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (422 aa) |
| | Veis_4911 | Threonine ammonia-lyase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: pau:PA14_53260 hypothetical protein. (323 aa) |
| | Veis_4883 | KEGG: rfr:Rfer_1329 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase, subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase, type 3. (264 aa) |
| | Veis_4872 | KEGG: pol:Bpro_3612 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. (379 aa) |
| | Veis_0014 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (911 aa) |
| | Veis_0037 | Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: pol:Bpro_3810 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (629 aa) |
| | Veis_0110 | PFAM: glutamine synthetase, catalytic region; KEGG: pol:Bpro_4698 glutamine synthetase, catalytic region. (458 aa) |
| | metXS | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (375 aa) |
| | Veis_0268 | TIGRFAM: acetylornithine deacetylase (ArgE); PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: bte:BTH_I2086 acetylornithine deacetylase. (398 aa) |
| | Veis_0274 | PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_1997 aminotransferase, class I and II. (409 aa) |
| | dapD | KEGG: rfr:Rfer_2046 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; PFAM: transferase hexapeptide repeat containing protein; Belongs to the transferase hexapeptide repeat family. (277 aa) |
| | dapE | Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (401 aa) |
| | ilvA | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (565 aa) |
| | Veis_0339 | PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: bur:Bcep18194_C6721 acetolactate synthase, large subunit. (576 aa) |
| | Veis_0534 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: bam:Bamb_3882 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (321 aa) |
| | Veis_0654 | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: rfr:Rfer_0654 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (283 aa) |
| | Veis_0659 | PFAM: aminotransferase class-III; KEGG: mlo:mlr6714 ornithine-oxo-acid transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (428 aa) |
| | Veis_0720 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: bch:Bcen2424_6609 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. (424 aa) |
| | Veis_0740 | L-arabinonate dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: bam:Bamb_4925 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (577 aa) |
| | Veis_0744 | TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: rme:Rmet_1610 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. (453 aa) |
| | Veis_0789 | Acetolactate synthase, large subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: rfr:Rfer_0882 thiamine pyrophosphate enzyme-like TPP-binding; Belongs to the TPP enzyme family. (564 aa) |
| | Veis_0790 | Acetolactate synthase, large subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: reh:H16_B0313 acetolactate synthase large subunit (TPP dependent). (564 aa) |
| | Veis_0825 | PFAM: glutamine synthetase, catalytic region; KEGG: rfr:Rfer_0350 glutamate--ammonia ligase. (456 aa) |
| | argA | N-acetylglutamate synthase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: rfr:Rfer_2105 amino-acid N-acetyltransferase (ArgA); Belongs to the acetyltransferase family. ArgA subfamily. (448 aa) |
| | Veis_0940 | D-xylonate dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: ccr:CC0819 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (592 aa) |
| | proA | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (437 aa) |
| | Veis_1026 | KEGG: pol:Bpro_3726 cysteine synthase B; TIGRFAM: cysteine synthases; cysteine synthase B; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. (300 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (357 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (216 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (502 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (309 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (282 aa) |
