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mxaF mxaF tpiA tpiA glk glk LP43_0591 LP43_0591 pgi pgi LP43_2199 LP43_2199 LP43_2041 LP43_2041 LP43_2026 LP43_2026 LP43_2025 LP43_2025 LP43_2024 LP43_2024 LP43_1841 LP43_1841 bamB bamB LP43_1717 LP43_1717 eno eno acsA acsA LP43_1337 LP43_1337 LP43_1233 LP43_1233 LP43_0463 LP43_0463 LP43_1180 LP43_1180 LP43_1153 LP43_1153 LP43_0462 LP43_0462 fbp fbp LP43_1037 LP43_1037 LP43_0460 LP43_0460 mxaI mxaI gpmI gpmI pgk pgk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mxaFMethanol dehydrogenase, large subunit. (627 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (241 aa)
glkGlucokinase; Belongs to the bacterial glucokinase family. (326 aa)
LP43_0591Phosphomannomutase/Phosphoglucomutase. (933 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (545 aa)
LP43_2199Phosphoglucomutase. (544 aa)
LP43_2041Aldose 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family. (301 aa)
LP43_2026Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex. (585 aa)
LP43_2025Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (438 aa)
LP43_2024Dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (884 aa)
LP43_1841Dihydrolipoamide dehydrogenase. (473 aa)
bamBOuter membrane protein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (389 aa)
LP43_1717Hypothetical protein. (175 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (426 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa)
LP43_1337Aldehyde dehydrogenase. (506 aa)
LP43_1233Zinc-containing alcohol dehydrogenase/quinone oxidoreductase (NADPH:quinone reductase). (328 aa)
LP43_0463Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (353 aa)
LP43_1180Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (790 aa)
LP43_1153Glucose dehydrogenase, PQQ-dependent. (581 aa)
LP43_0462Pyruvate kinase; Belongs to the pyruvate kinase family. (488 aa)
fbpFructose-1,6-bisphosphatase, type I; Belongs to the FBPase class 1 family. (336 aa)
LP43_1037Membrane-bound lytic murein transglycosylase B precursor. (325 aa)
LP43_0460NAD-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)
mxaIMethanol dehydrogenase, small subunit. (88 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (511 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (395 aa)
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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