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LP43_0033 LP43_0033 fbp fbp prs prs LP43_0459 LP43_0459 LP43_0463 LP43_0463 LP43_0591 LP43_0591 LP43_0704 LP43_0704 rpiA rpiA pgl pgl zwf zwf rpiA-2 rpiA-2 LP43_1202 LP43_1202 LP43_1359 LP43_1359 LP43_1451 LP43_1451 LP43_1456 LP43_1456 edd edd LP43_1955 LP43_1955 LP43_2199 LP43_2199 pgi pgi LP43_2463 LP43_2463 tal tal LP43_2466 LP43_2466 LP43_2467 LP43_2467
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LP43_00332-Keto-D-gluconate dehydrogenase. (558 aa)
fbpFructose-1,6-bisphosphatase, type I; Belongs to the FBPase class 1 family. (336 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (328 aa)
LP43_0459Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (662 aa)
LP43_0463Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (353 aa)
LP43_0591Phosphomannomutase/Phosphoglucomutase. (933 aa)
LP43_07046-phosphogluconate dehydrogenase, decarboxylating; Partial cds. (61 aa)
rpiARibose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (220 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (236 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (489 aa)
rpiA-2Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (230 aa)
LP43_12026-phosphogluconate dehydrogenase, decarboxylating; Partial cds. (61 aa)
LP43_1359Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (230 aa)
LP43_1451Hypothetical protein. (273 aa)
LP43_14564-Hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldolase. (210 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (607 aa)
LP43_1955PQQ-dependent oxidoreductase, gdhB family. (371 aa)
LP43_2199Phosphoglucomutase. (544 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (545 aa)
LP43_2463D-arabino-3-hexulose 6-phosphate formaldehyde lyase. (213 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (327 aa)
LP43_2466D-arabino-3-hexulose 6-phosphate formaldehyde lyase. (211 aa)
LP43_24676-phospho-3-hexuloisomerase. (179 aa)
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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