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mauA mauA LP43_2521 LP43_2521 glyA glyA LP43_0836 LP43_0836 LP43_0835 LP43_0835 xoxF-3 xoxF-3 xoxJ xoxJ xoxF xoxF LP43_0508 LP43_0508 LP43_0506 LP43_0506 LP43_0505 LP43_0505 LP43_0463 LP43_0463 mxaD mxaD mxaF mxaF mxaJ mxaJ mxaG mxaG mxaI mxaI mxaA mxaA mxaC mxaC mxaK mxaK mxaL mxaL gpmI gpmI LP43_0317 LP43_0317 LP43_0287 LP43_0287 LP43_0286 LP43_0286 ffsA ffsA LP43_0284 LP43_0284 fbp fbp LP43_0058 LP43_0058 LP43_0057 LP43_0057 LP43_0055 LP43_0055 LP43_0054 LP43_0054 LP43_0052 LP43_0052 mch mch LP43_0839 LP43_0839 LP43_0841 LP43_0841 LP43_0842 LP43_0842 LP43_0843 LP43_0843 ppc ppc mauB mauB LP43_1180 LP43_1180 xoxF-4 xoxF-4 LP43_1262 LP43_1262 LP43_0838 LP43_0838 acsA acsA mgsC mgsC mgsB mgsB mgsA mgsA LP43_1451 LP43_1451 eno eno mxaC-2 mxaC-2 mxaL-2 mxaL-2 mxaK-2 mxaK-2 mxaC-3 mxaC-3 mxaA-2 mxaA-2 LP43_1915 LP43_1915 LP43_1948 LP43_1948 serC serC LP43_2389 LP43_2389 LP43_2430 LP43_2430 LP43_2463 LP43_2463 LP43_2466 LP43_2466 LP43_2467 LP43_2467
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mauAMethylamine dehydrogenase light chain precursor; Belongs to the aromatic amine dehydrogenase light chain family. (188 aa)
LP43_2521Phosphoserine phosphatase. (280 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa)
LP43_0836Putative formate dehydrogenase-specific chaperone. (189 aa)
LP43_0835Iron-sulfur cluster-binding protein. (517 aa)
xoxF-3Methanol dehydrogenase large subunit protein. (592 aa)
xoxJXoxJ protein. (293 aa)
xoxFMethanol dehydrogenase large subunit protein. (592 aa)
LP43_0508Methylene tetrahydromethanopterin dehydrogenase. (288 aa)
LP43_0506Methylene tetrahydromethanopterin dehydrogenase. (301 aa)
LP43_0505Hypothetical protein. (366 aa)
LP43_0463Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (353 aa)
mxaDMxaD protein. (175 aa)
mxaFMethanol dehydrogenase, large subunit. (627 aa)
mxaJMxaJ protein. (246 aa)
mxaGCytochrome c-L precursor (Cytochrome c551I) (Cytochrome c552). (193 aa)
mxaIMethanol dehydrogenase, small subunit. (88 aa)
mxaAMxaA protein. (311 aa)
mxaCMxaC protein. (326 aa)
mxaKMxaK protein. (189 aa)
mxaLMxaL protein. (323 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (511 aa)
LP43_0317Hypothetical protein. (231 aa)
LP43_0287Formylmethanofuran hydrolase subunit B. (424 aa)
LP43_0286Formylmethanofuran hydrolase subunit A. (555 aa)
ffsAFormylmethanofuran--tetrahydromethanopterin N-formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family. (301 aa)
LP43_0284Formylmethanofuran hydrolase subunit C. (271 aa)
fbpFructose-1,6-bisphosphatase, type I; Belongs to the FBPase class 1 family. (336 aa)
LP43_0058Siderophore biosynthesis L-2,4-diaminobutyrate decarboxylase. (392 aa)
LP43_0057Delta 1-pyrroline-5-carboxylate synthetase. (192 aa)
LP43_0055Hypothetical protein. (348 aa)
LP43_0054Hypothetical protein. (324 aa)
LP43_0052Formaldehyde activating enzyme. (172 aa)
mchN(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family. (327 aa)
LP43_0839Formate dehydrogenase-O, iron-sulfur subunit/putative formate dehydrogenase iron-sulfur subunit. (194 aa)
LP43_0841Formate dehydrogenase O gamma subunit. (319 aa)
LP43_0842Tungsten-containing formate dehydrogenase beta subunit. (565 aa)
LP43_0843Tungsten-containing formate dehydrogenase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (932 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (947 aa)
mauBMethylamine dehydrogenase heavy chain precursor. (392 aa)
LP43_1180Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (790 aa)
xoxF-4Methanol dehydrogenase large subunit protein. (592 aa)
LP43_1262Formaldehyde activating enzyme. (182 aa)
LP43_0838Formate dehydrogenase-O, major subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (965 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa)
mgsCN-methyl glutamate synthase subunit C; Belongs to the glutamate synthase family. (443 aa)
mgsBN-methyl glutamate synthase subunit B. (245 aa)
mgsAN-methyl glutamate synthase subunit A. (298 aa)
LP43_1451Hypothetical protein. (273 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (426 aa)
mxaC-2MxaC protein. (341 aa)
mxaL-2MxaL protein. (311 aa)
mxaK-2MxaK protein. (179 aa)
mxaC-3MxaC protein. (338 aa)
mxaA-2MxaA protein. (278 aa)
LP43_1915MxaD protein. (188 aa)
LP43_1948Formylmethanofuran hydrolase subunit A. (553 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (342 aa)
LP43_2389D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (409 aa)
LP43_2430MxaD protein. (187 aa)
LP43_2463D-arabino-3-hexulose 6-phosphate formaldehyde lyase. (213 aa)
LP43_2466D-arabino-3-hexulose 6-phosphate formaldehyde lyase. (211 aa)
LP43_24676-phospho-3-hexuloisomerase. (179 aa)
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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