STRINGSTRING
Swit_3159 Swit_3159 Swit_4623 Swit_4623 Swit_4616 Swit_4616 parE parE gyrA gyrA Swit_4557 Swit_4557 Swit_4516 Swit_4516 Swit_4495 Swit_4495 Swit_4362 Swit_4362 Swit_4359 Swit_4359 Swit_4356 Swit_4356 Swit_4347 Swit_4347 Swit_4344 Swit_4344 Swit_4331 Swit_4331 Swit_4322 Swit_4322 Swit_4320 Swit_4320 Swit_4316 Swit_4316 Swit_4293 Swit_4293 Swit_4283 Swit_4283 Swit_4276 Swit_4276 Swit_4265 Swit_4265 Swit_4254 Swit_4254 Swit_4239 Swit_4239 Swit_4234 Swit_4234 Swit_4218 Swit_4218 Swit_4210 Swit_4210 Swit_4205 Swit_4205 Swit_4203 Swit_4203 Swit_4199 Swit_4199 Swit_4191 Swit_4191 Swit_4177 Swit_4177 Swit_4170 Swit_4170 Swit_4168 Swit_4168 Swit_4166 Swit_4166 Swit_4147 Swit_4147 Swit_4142 Swit_4142 Swit_4116 Swit_4116 Swit_4102 Swit_4102 radA radA Swit_4082 Swit_4082 Swit_4078 Swit_4078 Swit_4055 Swit_4055 ku ku Swit_3972 Swit_3972 Swit_3956 Swit_3956 Swit_3924 Swit_3924 Swit_3894 Swit_3894 Swit_3887 Swit_3887 Swit_3866 Swit_3866 Swit_3859 Swit_3859 Swit_3836 Swit_3836 topA topA Swit_3757 Swit_3757 Swit_3752 Swit_3752 Swit_3715 Swit_3715 Swit_3704 Swit_3704 Swit_3703 Swit_3703 Swit_3663 Swit_3663 Swit_3660 Swit_3660 Swit_3640 Swit_3640 Swit_3622 Swit_3622 Swit_3604 Swit_3604 dinB dinB Swit_3591 Swit_3591 Swit_3588 Swit_3588 Swit_3577 Swit_3577 Swit_3569 Swit_3569 ihfA ihfA Swit_3530 Swit_3530 Swit_3518 Swit_3518 Swit_3444 Swit_3444 Swit_3441 Swit_3441 Swit_3426 Swit_3426 Swit_3423 Swit_3423 Swit_3411 Swit_3411 Swit_3405 Swit_3405 Swit_3370 Swit_3370 Swit_3366 Swit_3366 Swit_3356 Swit_3356 Swit_3344 Swit_3344 Swit_3315 Swit_3315 Swit_3299 Swit_3299 Swit_3273 Swit_3273 Swit_3262 Swit_3262 Swit_3257 Swit_3257 Swit_3239 Swit_3239 Swit_3233 Swit_3233 Swit_3222 Swit_3222 lexA lexA Swit_3188 Swit_3188 Swit_3156 Swit_3156 uvrA uvrA Swit_3099 Swit_3099 Swit_3085 Swit_3085 Swit_3081 Swit_3081 Swit_3054 Swit_3054 Swit_3029 Swit_3029 Swit_3023 Swit_3023 Swit_2977 Swit_2977 Swit_2974 Swit_2974 Swit_2967 Swit_2967 Swit_2958 Swit_2958 Swit_2954 Swit_2954 Swit_2936 Swit_2936 Swit_2921 Swit_2921 Swit_2919 Swit_2919 Swit_2907 Swit_2907 Swit_2901 Swit_2901 Swit_2849 Swit_2849 Swit_2814 Swit_2814 Swit_2812 Swit_2812 gyrB gyrB recF recF Swit_2795 Swit_2795 Swit_2764 Swit_2764 mutS mutS Swit_2706 Swit_2706 Swit_2703 Swit_2703 Swit_2681 Swit_2681 Swit_2633 Swit_2633 Swit_2619 Swit_2619 Swit_2613 Swit_2613 Swit_2557 Swit_2557 Swit_2523 Swit_2523 Swit_2515 Swit_2515 Swit_2512 Swit_2512 Swit_2466 Swit_2466 Swit_2460 Swit_2460 Swit_2452 Swit_2452 Swit_2409 Swit_2409 fur fur Swit_2320 Swit_2320 Swit_2319 Swit_2319 Swit_2305 Swit_2305 Swit_2297 Swit_2297 Swit_2293 Swit_2293 Swit_2273 Swit_2273 Swit_2246 Swit_2246 Swit_2235 Swit_2235 Swit_2225 Swit_2225 Swit_2198 Swit_2198 Swit_2160 Swit_2160 Swit_2147 Swit_2147 Swit_2142 Swit_2142 ruvA ruvA Swit_2109 Swit_2109 Swit_2073 Swit_2073 Swit_2048 Swit_2048 Swit_2047 Swit_2047 Swit_2042 Swit_2042 Swit_2039 Swit_2039 Swit_2002 Swit_2002 Swit_1997 Swit_1997 Swit_1975 Swit_1975 Swit_1963 Swit_1963 Swit_1962 Swit_1962 Swit_1957 Swit_1957 Swit_1954 Swit_1954 Swit_1945 Swit_1945 Swit_1944 Swit_1944 Swit_1911 Swit_1911 Swit_1891 Swit_1891 Swit_1888 Swit_1888 Swit_1845 Swit_1845 Swit_1825 Swit_1825 Swit_1808 Swit_1808 Swit_1784 Swit_1784 Swit_1777 Swit_1777 Swit_1768 Swit_1768 Swit_1732 Swit_1732 Swit_1725 Swit_1725 Swit_1692 Swit_1692 Swit_1678 Swit_1678 Swit_1674 Swit_1674 Swit_1647 Swit_1647 Swit_1637 Swit_1637 Swit_1610 Swit_1610 Swit_1593 Swit_1593 Swit_1585 Swit_1585 Swit_1565 Swit_1565 Swit_1560 Swit_1560 Swit_1553 Swit_1553 Swit_1551 Swit_1551 Swit_1540 Swit_1540 Swit_1535 Swit_1535 mfd mfd Swit_1500 Swit_1500 Swit_1476 Swit_1476 Swit_1464 Swit_1464 Swit_1462 Swit_1462 Swit_1446 Swit_1446 Swit_1432 Swit_1432 Swit_1386 Swit_1386 Swit_1375 Swit_1375 Swit_1285 Swit_1285 Swit_1281 Swit_1281 Swit_1223 Swit_1223 Swit_1212 Swit_1212 Swit_1196 Swit_1196 Swit_1185 Swit_1185 Swit_1180 Swit_1180 Swit_1167 Swit_1167 Swit_1159 Swit_1159 Swit_1150 Swit_1150 Swit_1142 Swit_1142 nrdR nrdR Swit_1127 Swit_1127 Swit_1114 Swit_1114 Swit_1109 Swit_1109 Swit_1079 Swit_1079 Swit_1068 Swit_1068 Swit_1053 Swit_1053 Swit_1017 Swit_1017 Swit_0986 Swit_0986 Swit_0980 Swit_0980 Swit_0974 Swit_0974 Swit_0970 Swit_0970 Swit_0960 Swit_0960 Swit_0955 Swit_0955 Swit_0953 Swit_0953 Swit_0951 Swit_0951 Swit_0946 Swit_0946 Swit_0934 Swit_0934 Swit_0933 Swit_0933 Swit_0926 Swit_0926 Swit_0923 Swit_0923 Swit_0891 Swit_0891 Swit_0833 Swit_0833 Swit_0816 Swit_0816 Swit_4854 Swit_4854 Swit_0810 Swit_0810 Swit_0804 Swit_0804 Swit_0797 Swit_0797 Swit_0766 Swit_0766 Swit_0760 Swit_0760 Swit_0733 Swit_0733 Swit_0722 Swit_0722 Swit_0719 Swit_0719 Swit_0716 Swit_0716 Swit_0694 Swit_0694 Swit_0670 Swit_0670 Swit_0662 Swit_0662 Swit_0654 Swit_0654 Swit_0653 Swit_0653 Swit_0554 Swit_0554 recA recA Swit_0502 Swit_0502 Swit_0474 Swit_0474 polA polA greA greA dnaG dnaG rpoD rpoD Swit_0402 Swit_0402 greB greB Swit_0394 Swit_0394 Swit_0365 Swit_0365 Swit_0360 Swit_0360 Swit_0354 Swit_0354 Swit_0326 Swit_0326 Swit_0309 Swit_0309 Swit_0301 Swit_0301 Swit_0278 Swit_0278 Swit_0268 Swit_0268 Swit_0254 Swit_0254 Swit_0250 Swit_0250 ntrC ntrC xerC-2 xerC-2 priA priA nth nth Swit_0176 Swit_0176 Swit_0175 Swit_0175 Swit_0173 Swit_0173 Swit_0154 Swit_0154 Swit_0153 Swit_0153 Swit_0151 Swit_0151 parC parC Swit_0106 Swit_0106 Swit_0076 Swit_0076 rpoH rpoH Swit_0056 Swit_0056 Swit_0045 Swit_0045 xerC xerC dnaA dnaA mutM mutM Swit_4882 Swit_4882 Swit_4862 Swit_4862 Swit_4851 Swit_4851 Swit_4803 Swit_4803 Swit_4798 Swit_4798 Swit_4755 Swit_4755 Swit_4742 Swit_4742 Swit_4736 Swit_4736 Swit_4720 Swit_4720 smc smc Swit_4657 Swit_4657 Swit_4649 Swit_4649 Swit_4644 Swit_4644 Swit_4635 Swit_4635 Swit_4626 Swit_4626
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Swit_3159Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (282 aa)
Swit_4623Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (213 aa)
Swit_4616Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (216 aa)
parEDNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (660 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (936 aa)
Swit_4557Transcriptional regulator, AraC family; PFAM: Cupin 2, conserved barrel domain protein; SMART: helix-turn-helix- domain containing protein, AraC type. (274 aa)
Swit_4516Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein. (225 aa)
Swit_4495Two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region. (245 aa)
Swit_4362Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (228 aa)
Swit_4359PFAM: regulatory protein, LuxR. (301 aa)
Swit_4356Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (210 aa)
Swit_4347Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (307 aa)
Swit_4344Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II. (476 aa)
Swit_4331Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (220 aa)
Swit_4322Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein. (252 aa)
Swit_4320Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (307 aa)
Swit_4316Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR. (152 aa)
Swit_4293Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein. (220 aa)
Swit_4283Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein. (222 aa)
Swit_4276Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (309 aa)
Swit_4265Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (312 aa)
Swit_4254Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (343 aa)
Swit_4239PFAM: regulatory protein, LuxR. (312 aa)
Swit_4234Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (292 aa)
Swit_4218Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (202 aa)
Swit_4210Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (294 aa)
Swit_4205Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (382 aa)
Swit_4203Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (288 aa)
Swit_4199PFAM: regulatory protein, LuxR. (855 aa)
Swit_4191Transcriptional regulator, AraC family; SMART: helix-turn-helix- domain containing protein, AraC type. (336 aa)
Swit_4177PFAM: helix-turn-helix- domain containing protein, AraC type. (329 aa)
Swit_4170Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (220 aa)
Swit_4168Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (244 aa)
Swit_4166Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (318 aa)
Swit_4147Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (331 aa)
Swit_4142Transcriptional regulator, LacI family; PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator. (333 aa)
Swit_4116Putative transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein, Crp. (205 aa)
Swit_4102RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. (292 aa)
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (455 aa)
Swit_4082PFAM: regulatory protein, LuxR. (888 aa)
Swit_4078Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR. (175 aa)
Swit_4055Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (504 aa)
kuKu family containing protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (285 aa)
Swit_3972RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (175 aa)
Swit_3956Uncharacterized protein; Belongs to the MraZ family. (175 aa)
Swit_3924RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (231 aa)
Swit_3894Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (219 aa)
Swit_3887Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation. (327 aa)
Swit_3866Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR. (150 aa)
Swit_3859Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (346 aa)
Swit_3836RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (163 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (852 aa)
Swit_3757Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (321 aa)
Swit_3752PFAM: phage integrase family protein; Belongs to the 'phage' integrase family. (422 aa)
Swit_3715Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein. (232 aa)
Swit_3704Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (202 aa)
Swit_3703Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (315 aa)
Swit_3663DNA translocase FtsK; PFAM: cell divisionFtsK/SpoIIIE. (797 aa)
Swit_3660PFAM: regulatory protein, TetR; Resolvase helix-turn-helix domain protein. (203 aa)
Swit_3640Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (327 aa)
Swit_3622Transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR. (381 aa)
Swit_3604Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (207 aa)
dinBDNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (380 aa)
Swit_3591RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (176 aa)
Swit_3588Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (299 aa)
Swit_3577Two component transcriptional regulator, winged helix family; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein. (232 aa)
Swit_3569Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (217 aa)
ihfAIntegration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (100 aa)
Swit_3530Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (291 aa)
Swit_3518Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (321 aa)
Swit_3444Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein. (220 aa)
Swit_3441Two component, sigma54 specific, transcriptional regulator, Fis family; TIGRFAM: PEP-CTERM system response regulator, putative; PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase. (451 aa)
Swit_3426RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (229 aa)
Swit_3423Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; Belongs to the LysR transcriptional regulatory family. (319 aa)
Swit_3411Transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR. (290 aa)
Swit_3405Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (207 aa)
Swit_3370Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (208 aa)
Swit_3366PFAM: regulatory protein, TetR. (221 aa)
Swit_3356PFAM: regulatory protein, LuxR. (373 aa)
Swit_3344Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (202 aa)
Swit_3315Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (281 aa)
Swit_3299PFAM: regulatory protein, TetR. (216 aa)
Swit_3273Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (293 aa)
Swit_3262Transcriptional regulator, Fis family; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; 4-vinyl reductase, 4VR; Activator of aromatic catabolism; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase. (581 aa)
Swit_3257Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (207 aa)
Swit_3239Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (234 aa)
Swit_3233Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (308 aa)
Swit_3222Response regulator receiver protein; PFAM: LytTr DNA-binding region. (253 aa)
lexASOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (224 aa)
Swit_3188PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2. (208 aa)
Swit_3156Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR. (141 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (988 aa)
Swit_3099Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (222 aa)
Swit_3085Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (320 aa)
Swit_3081Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH. (240 aa)
Swit_3054Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (126 aa)
Swit_3029Putative transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein, Crp. (228 aa)
Swit_3023Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein. (236 aa)
Swit_2977PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2. (208 aa)
Swit_2974Two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region. (266 aa)
Swit_2967Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (198 aa)
Swit_2958TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074. (179 aa)
Swit_2954Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein. (226 aa)
Swit_2936Sigma54 specific transcriptional regulator, Fis family; TIGRFAM: Transcriptional activator, PspF; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase. (349 aa)
Swit_2921Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (283 aa)
Swit_2919TIGRFAM: putative transcriptional regulator, Rrf2 family; FeS assembly SUF system regulator, Rtf2 type; PFAM: protein of unknown function UPF0074. (134 aa)
Swit_2907RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (507 aa)
Swit_2901PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein. (288 aa)
Swit_2849Chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; Belongs to the ParB family. (298 aa)
Swit_2814Transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR. (146 aa)
Swit_2812Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (305 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (826 aa)
recFDNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (356 aa)
Swit_2795DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (370 aa)
Swit_2764Transcriptional regulator, GntR family; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; regulatory protein GntR, HTH; aminotransferase, class I and II. (453 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (904 aa)
Swit_2706Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; SMART: regulatory protein, Crp. (228 aa)
Swit_2703Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (184 aa)
Swit_2681TIGRFAM: Double-strand break repair helicase AddA; PFAM: UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. (1142 aa)
Swit_2633Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (305 aa)
Swit_2619Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (297 aa)
Swit_2613RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)
Swit_2557PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein. (198 aa)
Swit_2523PFAM: regulatory protein, LuxR; Tetratricopeptide TPR_4; Sigma-70, region 4 type 2. (879 aa)
Swit_2515PFAM: regulatory protein, TetR. (288 aa)
Swit_2512Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (278 aa)
Swit_2466Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (311 aa)
Swit_2460PFAM: phage integrase family protein; Belongs to the 'phage' integrase family. (593 aa)
Swit_2452TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n. (195 aa)
Swit_2409Histone family protein DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (92 aa)
furFerric uptake regulator, Fur family; PFAM: ferric-uptake regulator; Belongs to the Fur family. (140 aa)
Swit_2320Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (91 aa)
Swit_2319Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (345 aa)
Swit_2305Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (316 aa)
Swit_2297Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (305 aa)
Swit_2293Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein. (228 aa)
Swit_2273Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (236 aa)
Swit_2246PFAM: regulatory protein, LuxR; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein. (899 aa)
Swit_2235Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein. (236 aa)
Swit_2225Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (337 aa)
Swit_2198TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n. (151 aa)
Swit_2160Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (298 aa)
Swit_2147Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein. (235 aa)
Swit_2142PFAM: protein of unknown function DUF28. (247 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (199 aa)
Swit_2109Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (206 aa)
Swit_2073PFAM: regulatory protein, LuxR. (381 aa)
Swit_2048Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (249 aa)
Swit_2047Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (350 aa)
Swit_2042Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (355 aa)
Swit_2039Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (326 aa)
Swit_2002Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (340 aa)
Swit_1997PFAM: regulatory protein, LuxR. (278 aa)
Swit_1975Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (367 aa)
Swit_1963Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (306 aa)
Swit_1962Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (315 aa)
Swit_1957Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (307 aa)
Swit_1954Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein. (253 aa)
Swit_1945Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein, Crp. (242 aa)
Swit_1944Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (429 aa)
Swit_1911Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (369 aa)
Swit_1891Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein. (265 aa)
Swit_1888Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein. (257 aa)
Swit_1845Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (237 aa)
Swit_1825Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (198 aa)
Swit_1808RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (221 aa)
Swit_1784Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (308 aa)
Swit_1777Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (351 aa)
Swit_1768PFAM: regulatory protein, TetR. (226 aa)
Swit_1732Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (206 aa)
Swit_1725Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (326 aa)
Swit_1692Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (305 aa)
Swit_1678Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (216 aa)
Swit_1674Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; Helix-turn-helix, type 11 domain protein. (246 aa)
Swit_1647Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein. (289 aa)
Swit_1637Transcriptional regulator, LacI family; PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator. (337 aa)
Swit_1610Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (424 aa)
Swit_1593SMART: helix-turn-helix- domain containing protein, AraC type. (335 aa)
Swit_1585Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (350 aa)
Swit_1565Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein. (215 aa)
Swit_1560Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR. (163 aa)
Swit_1553Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (212 aa)
Swit_1551Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (225 aa)
Swit_1540Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (319 aa)
Swit_1535Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (301 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1195 aa)
Swit_1500RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (170 aa)
Swit_1476Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (300 aa)
Swit_1464Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein. (222 aa)
Swit_1462Transcriptional regulator; Belongs to the Fur family. (158 aa)
Swit_1446PFAM: regulatory protein, LuxR. (284 aa)
Swit_1432PFAM: regulatory protein, LuxR. (837 aa)
Swit_1386Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein. (263 aa)
Swit_1375Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (305 aa)
Swit_1285Sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase. (425 aa)
Swit_1281TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2. (242 aa)
Swit_1223TIGRFAM: addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin. (101 aa)
Swit_1212PFAM: UvrD/REP helicase. (892 aa)
Swit_1196Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (261 aa)
Swit_1185Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase. (480 aa)
Swit_1180Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (326 aa)
Swit_1167Transcriptional regulator, AraC family; SMART: helix-turn-helix- domain containing protein, AraC type. (334 aa)
Swit_1159Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2. (209 aa)
Swit_1150Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein. (257 aa)
Swit_1142Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (210 aa)
nrdRATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (154 aa)
Swit_1127DNA-O6-methylguanine--protein-cysteine S-methyltransferase / Transcriptional regulator Ada; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; Ada, metal-binding domain protein; Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding. (351 aa)
Swit_1114L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1032 aa)
Swit_1109Putative RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. (414 aa)
Swit_1079RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (216 aa)
Swit_1068Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (313 aa)
Swit_1053Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (255 aa)
Swit_1017Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (216 aa)
Swit_0986Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (329 aa)
Swit_0980Transcriptional regulator, AraC family; SMART: helix-turn-helix- domain containing protein, AraC type. (316 aa)
Swit_0974Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (299 aa)
Swit_0970Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (343 aa)
Swit_0960Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (295 aa)
Swit_0955Putative transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein, Crp. (226 aa)
Swit_0953Putative transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein, Crp. (254 aa)
Swit_0951Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (294 aa)
Swit_0946Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (206 aa)
Swit_0934Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (365 aa)
Swit_0933Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (293 aa)
Swit_0926PFAM: regulatory protein, LuxR; Tetratricopeptide TPR_4; Sigma-70, region 4 type 2. (878 aa)
Swit_0923RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (172 aa)
Swit_0891Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein. (231 aa)
Swit_0833PFAM: regulatory protein, LuxR. (904 aa)
Swit_0816Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (319 aa)
Swit_4854Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein. (231 aa)
Swit_0810Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (306 aa)
Swit_0804Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver. (229 aa)
Swit_0797PFAM: cyclic nucleotide-binding. (217 aa)
Swit_0766PFAM: regulatory protein, LuxR. (364 aa)
Swit_0760Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (192 aa)
Swit_0733Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (330 aa)
Swit_0722PFAM: helix-turn-helix- domain containing protein, AraC type. (358 aa)
Swit_0719Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation. (261 aa)
Swit_0716Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type. (296 aa)
Swit_0694Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2. (252 aa)
Swit_0670PFAM: regulatory protein, LuxR. (890 aa)
Swit_0662PFAM: phage integrase family protein; Belongs to the 'phage' integrase family. (417 aa)
Swit_0654Putative transcriptional regulator, Crp/Fnr family. (247 aa)
Swit_0653Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (325 aa)
Swit_0554Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (301 aa)
recArecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (357 aa)
Swit_0502PFAM: regulatory protein, LuxR; Sigma-70, region 4 type 2. (861 aa)
Swit_0474Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (311 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (941 aa)
greATranscription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (158 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (623 aa)
rpoDRNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (674 aa)
Swit_0402Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein. (235 aa)
greBTranscription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. (163 aa)
Swit_0394PFAM: regulatory protein, LuxR; Bacterio-opsin activator, HTH domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2. (185 aa)
Swit_0365Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (213 aa)
Swit_0360Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR. (177 aa)
Swit_0354PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (297 aa)
Swit_0326Transcriptional regulator, AraC family with amidase-like domain; PFAM: helix-turn-helix- domain containing protein, AraC type. (323 aa)
Swit_0309Transcriptional regulator, AraC family with amidase-like domain; PFAM: helix-turn-helix- domain containing protein, AraC type. (320 aa)
Swit_0301Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (250 aa)
Swit_0278Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein. (265 aa)
Swit_0268Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver. (203 aa)
Swit_0254Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (296 aa)
Swit_0250Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase. (462 aa)
ntrCNitrogen metabolism transcriptional regulator, NtrC, Fis Family; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (485 aa)
xerC-2Phage integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (308 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (734 aa)
nthEndonuclease III / DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (218 aa)
Swit_0176RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (206 aa)
Swit_0175Transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; Autoinducer-binding domain protein. (254 aa)
Swit_0173Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (318 aa)
Swit_0154PFAM: phage integrase family protein; Belongs to the 'phage' integrase family. (451 aa)
Swit_0153Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (205 aa)
Swit_0151Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (279 aa)
parCDNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (750 aa)
Swit_0106Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (294 aa)
Swit_0076Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH. (115 aa)
rpoHRNA polymerase sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (301 aa)
Swit_0056Conserved hypothetical protein 103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (112 aa)
Swit_0045Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa)
xerCPhage integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (301 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (477 aa)
mutMFormamidopyrimidine-DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (270 aa)
Swit_4882TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein. (74 aa)
Swit_4862PFAM: regulatory protein, LuxR. (250 aa)
Swit_4851Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (194 aa)
Swit_4803SMART: helix-turn-helix- domain containing protein, AraC type. (340 aa)
Swit_4798Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein. (230 aa)
Swit_4755Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II. (457 aa)
Swit_4742Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein. (271 aa)
Swit_4736RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (161 aa)
Swit_4720Putative PAS/PAC sensor protein; PFAM: regulatory protein, LuxR; PAS fold-3 domain protein. (222 aa)
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1140 aa)
Swit_4657Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (316 aa)
Swit_4649Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (315 aa)
Swit_4644PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein. (68 aa)
Swit_4635Transcriptional regulator, GntR family; TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein. (233 aa)
Swit_4626Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (219 aa)
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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