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Swoo_0656 Swoo_0656 Swoo_0219 Swoo_0219 Swoo_0220 Swoo_0220 Swoo_0221 Swoo_0221 Swoo_0222 Swoo_0222 Swoo_0223 Swoo_0223 Swoo_0224 Swoo_0224 Swoo_0015 Swoo_0015 fadA fadA fadB fadB Swoo_4889 Swoo_4889 Swoo_4859 Swoo_4859 Swoo_4857 Swoo_4857 hutI hutI hutU hutU hutH hutH dtd dtd Swoo_4602 Swoo_4602 Swoo_4562 Swoo_4562 Swoo_4334 Swoo_4334 gcvT gcvT gcvH gcvH gcvP gcvP Swoo_3913 Swoo_3913 Swoo_3741 Swoo_3741 Swoo_3665 Swoo_3665 Swoo_3406 Swoo_3406 Swoo_3258 Swoo_3258 Swoo_3239 Swoo_3239 Swoo_3238 Swoo_3238 Swoo_3227 Swoo_3227 Swoo_3202 Swoo_3202 Swoo_3198 Swoo_3198 Swoo_3197 Swoo_3197 fadI fadI Swoo_3026 Swoo_3026 Swoo_2943 Swoo_2943 Swoo_2934 Swoo_2934 Swoo_2932 Swoo_2932 Swoo_2931 Swoo_2931 Swoo_2822 Swoo_2822 Swoo_2820 Swoo_2820 Swoo_2723 Swoo_2723 Swoo_2714 Swoo_2714 Swoo_2604 Swoo_2604 Swoo_2542 Swoo_2542 edd edd prpB prpB Swoo_2497 Swoo_2497 Swoo_2496 Swoo_2496 Swoo_2485 Swoo_2485 Swoo_2368 Swoo_2368 Swoo_2336 Swoo_2336 Swoo_2300 Swoo_2300 Swoo_2279 Swoo_2279 Swoo_2278 Swoo_2278 astE astE Swoo_2140 Swoo_2140 speA speA Swoo_2019 Swoo_2019 Swoo_2016 Swoo_2016 Swoo_2010 Swoo_2010 Swoo_1883 Swoo_1883 Swoo_1838 Swoo_1838 astB astB Swoo_1718 Swoo_1718 Swoo_1715 Swoo_1715 Swoo_1583 Swoo_1583 Swoo_1504 Swoo_1504 nbaC nbaC kynU kynU kynA kynA anmK anmK Swoo_1186 Swoo_1186 slyX slyX nagB nagB Swoo_0714 Swoo_0714 Swoo_0691 Swoo_0691 Swoo_0670 Swoo_0670 astD astD Swoo_0226 Swoo_0226 Swoo_0227 Swoo_0227 Swoo_0449 Swoo_0449 Swoo_0630 Swoo_0630 Swoo_0633 Swoo_0633 tdh tdh Swoo_0214 Swoo_0214 Swoo_0216 Swoo_0216 Swoo_0217 Swoo_0217 Swoo_0218 Swoo_0218
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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Swoo_0656KEGG: sse:Ssed_0810 arginine N-succinyltransferase; TIGRFAM: arginine/ornithine succinyltransferase subunit; arginine N-succinyltransferase; PFAM: arginine N-succinyltransferase beta subunit. (339 aa)
Swoo_0219TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: bbt:BBta_2867 phenylacetic acid degradation protein PaaC. (248 aa)
Swoo_0220TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit; PFAM: phenylacetic acid degradation B; KEGG: bpt:Bpet1925 phenylacetic acid degradation protein. (100 aa)
Swoo_0221TIGRFAM: phenylacetate-CoA oxygenase, PaaG subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: bpt:Bpet1924 putative phenylacetic acid degradation protein. (317 aa)
Swoo_0222KEGG: pla:Plav_2698 beta-ketoadipyl CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
Swoo_0223PFAM: thioesterase superfamily protein; KEGG: dac:Daci_0569 phenylacetic acid degradation protein PaaD. (158 aa)
Swoo_0224TIGRFAM: phenylacetate degradation, enoyl-CoA hydratase paaB; PFAM: Enoyl-CoA hydratase/isomerase; KEGG: spe:Spro_3078 phenylacetate degradation probable enoyl-CoA hydratase PaaB. (262 aa)
Swoo_0015Amidohydrolase; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; amidohydrolase; WD40 domain protein beta Propeller; KEGG: sse:Ssed_0018 amidohydrolase. (1069 aa)
fadAacetyl-CoA C-acyltransferase FadA; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (387 aa)
fadBFatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (716 aa)
Swoo_4889PFAM: protein of unknown function DUF1063; KEGG: shn:Shewana3_2972 protein of unknown function DUF1063; Belongs to the UPF0597 family. (425 aa)
Swoo_4859PFAM: thioesterase superfamily protein; KEGG: sse:Ssed_4458 thioesterase superfamily protein. (134 aa)
Swoo_4857PFAM: thioesterase superfamily protein; KEGG: sse:Ssed_4456 thioesterase superfamily. (143 aa)
hutIKEGG: sse:Ssed_4449 imidazolonepropionase; TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (408 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (556 aa)
hutHKEGG: slo:Shew_3756 histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; Belongs to the PAL/histidase family. (510 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (145 aa)
Swoo_4602PFAM: phenylalanine/histidine ammonia-lyase; KEGG: sse:Ssed_0319 histidine ammonia-lyase. (520 aa)
Swoo_4562Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (408 aa)
Swoo_4334KEGG: sse:Ssed_0616 hypothetical protein. (403 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (364 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (969 aa)
Swoo_3913PFAM: phenylalanine/histidine ammonia-lyase; KEGG: spl:Spea_3575 phenylalanine/histidine ammonia-lyase. (552 aa)
Swoo_3741PFAM: amidohydrolase; Amidohydrolase 3; KEGG: slo:Shew_2992 amidohydrolase. (444 aa)
Swoo_3665PFAM: 2-keto-3-deoxy-galactonokinase; KEGG: ccr:CC_0785 hypothetical protein. (315 aa)
Swoo_3406PFAM: Amidohydrolase 3; KEGG: sse:Ssed_3258 amidohydrolase 3. (550 aa)
Swoo_3258PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: pat:Patl_2790 mandelate racemase/muconate lactonizing enzyme-like. (355 aa)
Swoo_3239KEGG: sse:Ssed_1442 hypothetical protein. (435 aa)
Swoo_3238PFAM: amidohydrolase; Amidohydrolase 3; KEGG: sse:Ssed_1443 amidohydrolase. (1021 aa)
Swoo_3227PFAM: pyruvate carboxyltransferase; KEGG: sse:Ssed_1454 pyruvate carboxyltransferase. (296 aa)
Swoo_3202KEGG: sse:Ssed_1473 acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
Swoo_3198PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sse:Ssed_1477 enoyl-CoA hydratase/isomerase. (381 aa)
Swoo_3197KEGG: sse:Ssed_1478 3-hydroxyisobutyrate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; Belongs to the HIBADH-related family. (305 aa)
fadIacetyl-CoA C-acyltransferase FadI; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (436 aa)
Swoo_3026Fatty acid oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (713 aa)
Swoo_2943PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sse:Ssed_1665 NADH:flavin oxidoreductase/NADH oxidase. (672 aa)
Swoo_2934PFAM: catalytic domain of components of various dehydrogenase complexes; KEGG: smu:SMU.1421 branched-chain alpha-keto acid dehydrogenase subunit E2. (228 aa)
Swoo_2932PFAM: Transketolase central region; Transketolase domain protein; KEGG: cps:CPS_3051 TPP-dependent acetoin dehydrogenase complex, E1 component, beta subunit. (337 aa)
Swoo_2931Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component; KEGG: cps:CPS_3052 TPP-dependent acetoin dehydrogenase complex, E1 component, alpha subunit. (329 aa)
Swoo_2822Dihydrodipicolinate synthetase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (304 aa)
Swoo_2820PFAM: FAD dependent oxidoreductase; KEGG: spl:Spea_1706 FAD dependent oxidoreductase. (432 aa)
Swoo_2723PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: sse:Ssed_1865 fumarylacetoacetate (FAA) hydrolase. (203 aa)
Swoo_2714PFAM: FAD linked oxidase domain protein; KEGG: sse:Ssed_1872 D-lactate dehydrogenase (cytochrome). (1023 aa)
Swoo_2604PFAM: acyl-CoA dehydrogenase domain protein; Protein of unknown function DUF1974; KEGG: sse:Ssed_1999 acyl-CoA dehydrogenase domain protein. (815 aa)
Swoo_2542PFAM: acyl-CoA dehydrogenase domain protein; Protein of unknown function DUF1974; KEGG: sse:Ssed_2067 acyl-CoA dehydrogenase domain protein. (758 aa)
edd6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (608 aa)
prpBMethylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (292 aa)
Swoo_2497TIGRFAM: 2-methylisocitrate dehydratase, Fe/S-dependent; PFAM: aconitate hydratase domain protein; KEGG: sse:Ssed_2113 2-methylisocitrate dehydratase AcnD, Fe/S-dependent. (869 aa)
Swoo_2496TIGRFAM: AcnD-accessory protein PrpF; PFAM: protein of unknown function DUF453; KEGG: sse:Ssed_2114 putative AcnD-accessory protein PrpF. (405 aa)
Swoo_2485TIGRFAM: alanine dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Shikimate/quinate 5-dehydrogenase; alanine dehydrogenase/PNT domain protein; KEGG: spl:Spea_2235 alanine dehydrogenase; Belongs to the AlaDH/PNT family. (371 aa)
Swoo_2368PFAM: amidohydrolase; Amidohydrolase 3; KEGG: sfr:Sfri_2093 amidohydrolase. (441 aa)
Swoo_2336KEGG: pha:PSHAb0338 homogentisate 1,2-dioxygenase (Homogentisicase) (homogentisate oxygenase) (Homogentisic acid oxidase) [HGD]; TIGRFAM: homogentisate 1,2-dioxygenase; PFAM: homogentisate 12-dioxygenase. (430 aa)
Swoo_2300PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sse:Ssed_2310 NADH:flavin oxidoreductase/NADH oxidase. (671 aa)
Swoo_2279PFAM: Transketolase central region; Transketolase domain protein; KEGG: sse:Ssed_2328 transketolase, central region. (325 aa)
Swoo_2278PFAM: dehydrogenase E1 component; KEGG: sse:Ssed_2329 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring). (392 aa)
astESuccinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily. (345 aa)
Swoo_2140PFAM: NAD-glutamate dehydrogenase; KEGG: sse:Ssed_2476 NAD-glutamate dehydrogenase. (1614 aa)
speAArginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (637 aa)
Swoo_2019PFAM: 4-hydroxyphenylacetate 3-hydroxylase; KEGG: fra:Francci3_2770 4-hydroxyphenylacetate 3-hydroxylase. (504 aa)
Swoo_2016Coenzyme F390 synthetase-like protein; KEGG: mmz:MmarC7_1160 phenylacetate--CoA ligase. (452 aa)
Swoo_2010Coenzyme F390 synthetase-like protein; KEGG: gsu:GSU1729 phenylacetate-CoA ligase. (455 aa)
Swoo_1883PFAM: histidine triad (HIT) protein; KEGG: sse:Ssed_2755 histidine triad (HIT) protein. (118 aa)
Swoo_18382-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (396 aa)
astBSuccinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2). (445 aa)
Swoo_1718PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: sse:Ssed_2927 fumarylacetoacetate (FAA) hydrolase. (328 aa)
Swoo_1715Phenylalanine-4-hydroxylase; KEGG: sse:Ssed_2930 phenylalanine 4-monooxygenase; TIGRFAM: phenylalanine-4-hydroxylase; PFAM: aromatic amino acid hydroxylase. (265 aa)
Swoo_1583PFAM: LmbE family protein; KEGG: sru:SRU_0604 hypothetical protein. (225 aa)
Swoo_1504PFAM: acyl-CoA dehydrogenase domain protein; Protein of unknown function DUF1974; KEGG: spl:Spea_1234 protein of unknown function DUF1974. (745 aa)
nbaC3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (189 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (430 aa)
kynATryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (286 aa)
anmKProtein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (369 aa)
Swoo_1186PFAM: amidohydrolase; KEGG: hne:HNE_0404 amidohydrolase family protein. (512 aa)
slyXPFAM: SlyX family protein; KEGG: sse:Ssed_0916 SlyX family protein; Belongs to the SlyX family. (70 aa)
nagBGlucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. (264 aa)
Swoo_0714Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1059 aa)
Swoo_0691PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: gfo:GFO_1742 succinylglutamate desuccinylase/aspartoacylase family protein. (302 aa)
Swoo_0670PFAM: alpha/beta hydrolase fold; KEGG: sse:Ssed_3865 alpha/beta hydrolase fold. (323 aa)
astDSuccinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. (486 aa)
Swoo_0226TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: MaoC domain protein dehydratase; Aldehyde Dehydrogenase; KEGG: dge:Dgeo_1913 phenylacetic acid degradation protein PaaN. (683 aa)
Swoo_0227phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (433 aa)
Swoo_0449KEGG: slo:Shew_0298 Zn-dependent hydrolase of the beta-lactamase fold. (376 aa)
Swoo_0630PFAM: LmbE family protein; KEGG: sse:Ssed_4036 uncharacterized protein LmbE-like protein. (240 aa)
Swoo_06332-hydroxyglutarate dehydrogenase; PFAM: FAD dependent oxidoreductase; KEGG: slo:Shew_0530 FAD dependent oxidoreductase. (378 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (341 aa)
Swoo_0214PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: mlo:mll4199 enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (696 aa)
Swoo_0216Transcriptional regulator, PaaX family; PFAM: PaaX domain protein; PaaX domain protein domain; KEGG: pen:PSEEN2789 transcriptional repressor for phenylacetic acid degradation. (311 aa)
Swoo_0217PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; Ferric reductase NAD binding; KEGG: mmw:Mmwyl1_3091 phenylacetate-CoA oxygenase/reductase, PaaK subunit. (357 aa)
Swoo_0218TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; KEGG: reh:H16_B1360 phenylacetic acid degradation protein D. (175 aa)
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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