STRINGSTRING
glmU glmU SDJ86269.1 SDJ86269.1 SDJ86715.1 SDJ86715.1 SDJ86758.1 SDJ86758.1 SDJ86805.1 SDJ86805.1 SDJ86844.1 SDJ86844.1 SDJ86879.1 SDJ86879.1 SDJ86915.1 SDJ86915.1 SDJ86948.1 SDJ86948.1 tal tal SDJ87362.1 SDJ87362.1 SDJ87391.1 SDJ87391.1 SDJ90323.1 SDJ90323.1 SDJ92217.1 SDJ92217.1 SDK00501.1 SDK00501.1 SDK05058.1 SDK05058.1 SDK05090.1 SDK05090.1 SDK05125.1 SDK05125.1 SDK05409.1 SDK05409.1 SDK05444.1 SDK05444.1 SDK05488.1 SDK05488.1 SDK05524.1 SDK05524.1 SDK05569.1 SDK05569.1 SDK05610.1 SDK05610.1 SDK05649.1 SDK05649.1 SDK05703.1 SDK05703.1 SDK05744.1 SDK05744.1 uxuA uxuA SDK05834.1 SDK05834.1 SDK05875.1 SDK05875.1 uxaB uxaB SDK05961.1 SDK05961.1 uxaC uxaC SDK06024.1 SDK06024.1 SDK06071.1 SDK06071.1 SDK06302.1 SDK06302.1 SDK06345.1 SDK06345.1 SDK06388.1 SDK06388.1 SDK08369.1 SDK08369.1 SDK08736.1 SDK08736.1 SDK10078.1 SDK10078.1 pgi pgi SDK22639.1 SDK22639.1 nanE nanE SDK22863.1 SDK22863.1 SDK22911.1 SDK22911.1 SDK22956.1 SDK22956.1 nagB nagB SDK71524.1 SDK71524.1 pgk pgk tpiA tpiA gpmI gpmI eno eno SDK81319.1 SDK81319.1 SDK81367.1 SDK81367.1 SDK81414.1 SDK81414.1 SDK86128.1 SDK86128.1 glmM glmM glmS-2 glmS-2 SDK93423.1 SDK93423.1 SDK93461.1 SDK93461.1 SDK93506.1 SDK93506.1 SDK93545.1 SDK93545.1 SDK99203.1 SDK99203.1 SDK99246.1 SDK99246.1 SDL00191.1 SDL00191.1 rbsK rbsK SDL00271.1 SDL00271.1 SDL00414.1 SDL00414.1 rbsK-2 rbsK-2 araB araB fucI fucI rbsK-3 rbsK-3 rbsD rbsD rbsA rbsA SDL03947.1 SDL03947.1 SDL03997.1 SDL03997.1 SDL10228.1 SDL10228.1 pfkA pfkA SDL13045.1 SDL13045.1 SDL32879.1 SDL32879.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (459 aa)
SDJ86269.1UDP-glucose pyrophosphorylase. (302 aa)
SDJ86715.1Monosaccharide ABC transporter substrate-binding protein, CUT2 family. (321 aa)
SDJ86758.1Monosaccharide ABC transporter ATP-binding protein, CUT2 family (TC 3.A.1.2.-). (498 aa)
SDJ86805.1Monosaccharide ABC transporter membrane protein, CUT2 family (TC 3.A.1.2.-); Belongs to the binding-protein-dependent transport system permease family. (321 aa)
SDJ86844.1Sugar or nucleoside kinase, ribokinase family. (313 aa)
SDJ86879.1Tagatose 1,6-diphosphate aldolase GatY/KbaY. (283 aa)
SDJ86915.1Tagatose 6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (314 aa)
SDJ86948.1Transcriptional regulator, GntR family. (240 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (214 aa)
SDJ87362.1Fructose-1,6-bisphosphatase II. (337 aa)
SDJ87391.1Fructose-1,6-bisphosphatase II. (322 aa)
SDJ90323.1Phosphoglucomutase. (564 aa)
SDJ92217.1DNA-binding transcriptional regulator, GntR family. (220 aa)
SDK00501.1Transcriptional regulator, LacI family. (329 aa)
SDK05058.12-keto-3-deoxy-phosphogluconate aldolase. (215 aa)
SDK05090.12-dehydro-3-deoxygluconokinase. (341 aa)
SDK05125.12-dehydro-3-deoxygluconokinase; Belongs to the carbohydrate kinase PfkB family. (306 aa)
SDK05409.1Glucosamine-6-phosphate deaminase. (252 aa)
SDK05444.1Transcriptional regulator, LacI family. (352 aa)
SDK05488.1Glucosamine-6-phosphate deaminase. (251 aa)
SDK05524.1Hypothetical protein. (263 aa)
SDK05569.1Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (508 aa)
SDK05610.1N-acylglucosamine 2-epimerase. (413 aa)
SDK05649.1Neutral/alkaline non-lysosomal ceramidase, N-terminal. (415 aa)
SDK05703.1Uncharacterized protein, contains SIS (Sugar ISomerase) phosphosugar binding domain. (253 aa)
SDK05744.1N-acetylglucosamine-6-phosphate deacetylase. (393 aa)
uxuAD-mannonate dehydratase; Catalyzes the dehydration of D-mannonate. (349 aa)
SDK05834.1NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (283 aa)
SDK05875.1Transcriptional regulator, LacI family. (334 aa)
uxaBTagaturonate reductase; Belongs to the mannitol dehydrogenase family. UxaB subfamily. (483 aa)
SDK05961.1D-altronate dehydratase. (495 aa)
uxaCD-glucuronate isomerase. (493 aa)
SDK06024.1Transcriptional regulator, GntR family. (235 aa)
SDK06071.1Glycerol dehydrogenase. (359 aa)
SDK06302.1Galactonate dehydratase. (382 aa)
SDK06345.12-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase. (214 aa)
SDK06388.12-dehydro-3-deoxygalactonokinase. (329 aa)
SDK08369.1Glyceraldehyde-3-phosphate dehydrogenase (NAD+); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
SDK08736.1Fructose-bisphosphate aldolase. (309 aa)
SDK10078.1N-acetylglucosamine-6-phosphate deacetylase. (386 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (451 aa)
SDK22639.1N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. Belongs to the DapA family. (287 aa)
nanEN-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (223 aa)
SDK22863.1ROK family protein (putative glucokinase). (300 aa)
SDK22911.1Transcriptional regulator, RpiR family. (274 aa)
SDK22956.1GntR family transcriptional regulator. (245 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (241 aa)
SDK71524.1Glyceraldehyde-3-phosphate dehydrogenase (NAD+); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (248 aa)
gpmIPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (511 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
SDK81319.1ADP-ribosylglycohydrolase. (330 aa)
SDK81367.1Sugar or nucleoside kinase, ribokinase family. (307 aa)
SDK81414.1Nicotinamide mononucleotide transporter. (231 aa)
SDK86128.1Transcriptional regulator, GntR family. (227 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (448 aa)
glmS-2Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (608 aa)
SDK93423.1Protein of unknown function. (384 aa)
SDK93461.1Monosaccharide ABC transporter ATP-binding protein, CUT2 family (TC 3.A.1.2.-). (556 aa)
SDK93506.1Simple sugar transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. (347 aa)
SDK93545.1Simple sugar transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. (363 aa)
SDK99203.1Uncharacterized conserved protein YgbK, DUF1537 family. (477 aa)
SDK99246.1Fructose-bisphosphate aldolase, class II. (279 aa)
SDL00191.1Transcriptional regulator, LacI family. (318 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (299 aa)
SDL00271.1Non-specific riboncleoside hydrolase. (304 aa)
SDL00414.1LacI family transcriptional regulator. (339 aa)
rbsK-2Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (302 aa)
araBL-ribulokinase. (555 aa)
fucIL-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose. (597 aa)
rbsK-3Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (306 aa)
rbsDD-ribose pyranase; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (132 aa)
rbsARibose transport system ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (496 aa)
SDL03947.1Ribose ABC transporter membrane protein; Belongs to the binding-protein-dependent transport system permease family. (313 aa)
SDL03997.1Ribose-binding protein. (301 aa)
SDL10228.1Pyruvate kinase; Belongs to the pyruvate kinase family. (585 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)
SDL13045.1GntR family transcriptional regulator. (242 aa)
SDL32879.1Fructose-bisphosphate aldolase, class I. (266 aa)
Your Current Organism:
Natronincola ferrireducens
NCBI taxonomy Id: 393762
Other names: DSM 18346, N. ferrireducens, Natronincola ferrireducens Zhilina et al. 2009, VKM B-2402, strain Z-0511
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