STRINGSTRING
TBX1 TBX1 NRP2 NRP2 TGFBR2 TGFBR2 LRP2 LRP2 NRP1 NRP1 TGFB2 TGFB2 SMAD4 SMAD4 ISL1 ISL1 ROBO2 ROBO2 ROBO1 ROBO1 FGF8 FGF8 BMPR2 BMPR2 SEMA3C SEMA3C TBX20 TBX20 NKX2-5 NKX2-5 ENSSBOP00000011071 ENSSBOP00000011071 PARVA PARVA TBX2 TBX2 BMPR1A BMPR1A ZFPM2 ZFPM2 ENG ENG FGFR2 FGFR2 BMP4 BMP4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBX1Uncharacterized protein. (314 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (925 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
LRP2LDL receptor related protein 2. (4618 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ISL1ISL LIM homeobox 1. (349 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
ROBO1Roundabout guidance receptor 1. (1651 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (233 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
TBX20T-box transcription factor 20. (446 aa)
NKX2-5NK2 homeobox 5. (316 aa)
ENSSBOP00000011071MH2 domain-containing protein. (232 aa)
PARVAParvin alpha. (412 aa)
TBX2T-box transcription factor 2. (633 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
ENGEndoglin. (655 aa)
FGFR2Fibroblast growth factor receptor. (839 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.