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B4GALT5 B4GALT5 ORMDL1 ORMDL1 GBA3 GBA3 ACER2 ACER2 NEU3 NEU3 B4GALT3 B4GALT3 ASAH2 ASAH2 ORMDL2 ORMDL2 ST6GALNAC5 ST6GALNAC5 ENSSBOP00000030695 ENSSBOP00000030695 ST8SIA3 ST8SIA3 SGPL1 SGPL1 FA2H FA2H ENSSBOP00000029201 ENSSBOP00000029201 ASAH1 ASAH1 PPP2R1A PPP2R1A CEL CEL UGT8 UGT8 SPTLC2 SPTLC2 GBA2 GBA2 SPTLC3 SPTLC3 ACER1 ACER1 ITGB8 ITGB8 B4GALNT1 B4GALNT1 ST8SIA6 ST8SIA6 SPTLC1 SPTLC1 CERS6 CERS6 GALC GALC CYP4F22 CYP4F22 SMPD1 SMPD1 ENSSBOP00000019284 ENSSBOP00000019284 ALOX12B ALOX12B NSMAF NSMAF SGMS2 SGMS2 SAMD8 SAMD8 P2RX1 P2RX1 ABCA2 ABCA2 CERS3 CERS3 SGMS1 SGMS1 ACER3 ACER3 TLCD3B TLCD3B ENSSBOP00000014200 ENSSBOP00000014200 CERS4 CERS4 NEU1 NEU1 TMEM130 TMEM130 ST8SIA2 ST8SIA2 ENSSBOP00000013067 ENSSBOP00000013067 SMPD3 SMPD3 C20orf173 C20orf173 ST3GAL1 ST3GAL1 HTRA2 HTRA2 ST3GAL3 ST3GAL3 ORMDL3 ORMDL3 ENSSBOP00000010565 ENSSBOP00000010565 PLA2G15 PLA2G15 GBA GBA B4GALT4 B4GALT4 PPAP2B PPAP2B PLPP1 PLPP1 CLN8 CLN8 ABCA12 ABCA12 PNPLA1 PNPLA1 UGCG UGCG AGK AGK NAGA NAGA SPTSSB SPTSSB ENSSBOP00000004284 ENSSBOP00000004284 GM2A GM2A HEXB HEXB CERK CERK ENSSBOP00000000783 ENSSBOP00000000783 NEU2 NEU2 ST6GALNAC6 ST6GALNAC6 DEGS2 DEGS2 CERS1 CERS1 B3GALT2 B3GALT2 ELOVL1 ELOVL1 LCT LCT GAL3ST1 GAL3ST1 TM9SF2 TM9SF2 CLN6 CLN6 SPTSSA SPTSSA ST3GAL2 ST3GAL2 GLA GLA B4GALT6 B4GALT6 P2RX7 P2RX7 NEU4 NEU4 CERS5 CERS5 ST6GALNAC3 ST6GALNAC3 FUT7 FUT7 ST8SIA4 ST8SIA4 SMPD2 SMPD2 CERS2 CERS2 ST6GALNAC4 ST6GALNAC4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
B4GALT5Beta-1,4-galactosyltransferase 5. (368 aa)
ORMDL1ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
GBA3Glucosylceramidase beta 3 (gene/pseudogene); Belongs to the glycosyl hydrolase 1 family. (469 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
NEU3Neuraminidase 3. (461 aa)
B4GALT3Beta-1,4-galactosyltransferase 3. (393 aa)
ASAH2Neutral ceramidase. (778 aa)
ORMDL2ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
ST6GALNAC5ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; Belongs to the glycosyltransferase 29 family. (351 aa)
ENSSBOP00000030695Beta-hexosaminidase. (541 aa)
ST8SIA3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. (380 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
ENSSBOP00000029201Uncharacterized protein. (291 aa)
ASAH1N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (432 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (643 aa)
UGT8UDP glycosyltransferase 8; Belongs to the UDP-glycosyltransferase family. (541 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (497 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (923 aa)
SPTLC3Serine palmitoyltransferase long chain base subunit 3. (553 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (770 aa)
B4GALNT1Beta-1,4 N-acetylgalactosaminyltransferase. (533 aa)
ST8SIA6ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6; Belongs to the glycosyltransferase 29 family. (400 aa)
SPTLC1Aminotran_1_2 domain-containing protein. (498 aa)
CERS6Ceramide synthase 6. (375 aa)
GALCGalactosylceramidase. (685 aa)
CYP4F22Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family. (571 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
ENSSBOP00000019284Glyco_tran_10_N domain-containing protein. (360 aa)
ALOX12BArachidonate 12-lipoxygenase, 12R type. (701 aa)
NSMAFNeutral sphingomyelinase activation associated factor. (911 aa)
SGMS2Sphingomyelin synthase 2. (365 aa)
SAMD8Sterile alpha motif domain containing 8. (500 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
ABCA2ATP binding cassette subfamily A member 2. (2353 aa)
CERS3Ceramide synthase 3. (382 aa)
SGMS1Sphingomyelin synthase 1. (413 aa)
ACER3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (225 aa)
TLCD3BTLC domain containing 3B. (274 aa)
ENSSBOP00000014200SER_THR_PHOSPHATASE domain-containing protein. (282 aa)
CERS4Ceramide synthase 4. (400 aa)
NEU1Neuraminidase 1. (414 aa)
TMEM130Transmembrane protein 130. (358 aa)
ST8SIA2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (375 aa)
ENSSBOP00000013067Serine/threonine-protein phosphatase. (332 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
C20orf173Chromosome 20 open reading frame 173; Belongs to the glycosyltransferase 29 family. (194 aa)
ST3GAL1ST3 beta-galactoside alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (340 aa)
HTRA2HtrA serine peptidase 2. (533 aa)
ST3GAL3ST3 beta-galactoside alpha-2,3-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. (448 aa)
ORMDL3ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
ENSSBOP00000010565Uncharacterized protein. (106 aa)
PLA2G15Phospholipase A2 group XV. (412 aa)
GBAGlucosylceramidase. (536 aa)
B4GALT4Beta-1,4-galactosyltransferase 4. (344 aa)
PPAP2BacidPPc domain-containing protein. (311 aa)
PLPP1Phospholipid phosphatase 1. (284 aa)
CLN8CLN8 transmembrane ER and ERGIC protein. (286 aa)
ABCA12ATP binding cassette subfamily A member 12. (2595 aa)
PNPLA1Patatin like phospholipase domain containing 1. (520 aa)
UGCGUDP-glucose ceramide glucosyltransferase. (297 aa)
AGKAcylglycerol kinase. (421 aa)
NAGAAlpha-galactosidase. (411 aa)
SPTSSBSerine palmitoyltransferase small subunit B. (76 aa)
ENSSBOP00000004284Uncharacterized protein. (92 aa)
GM2AGM2 ganglioside activator. (190 aa)
HEXBBeta-hexosaminidase. (553 aa)
CERKCeramide kinase. (467 aa)
ENSSBOP00000000783Uncharacterized protein. (129 aa)
NEU2Neuraminidase 2. (379 aa)
ST6GALNAC6Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (299 aa)
DEGS2Delta 4-desaturase, sphingolipid 2. (323 aa)
CERS1TLC domain-containing protein. (239 aa)
B3GALT2Hexosyltransferase. (422 aa)
ELOVL1Elongation of very long chain fatty acids protein. (286 aa)
LCTLactase. (1926 aa)
GAL3ST1Galactose-3-O-sulfotransferase 1. (482 aa)
TM9SF2Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (663 aa)
CLN6CLN6 transmembrane ER protein. (386 aa)
SPTSSASerine palmitoyltransferase small subunit A. (71 aa)
ST3GAL2ST3 beta-galactoside alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (350 aa)
GLAAlpha-galactosidase. (429 aa)
B4GALT6Beta-1,4-galactosyltransferase 6. (382 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
NEU4Neuraminidase 4. (491 aa)
CERS5Ceramide synthase 5. (426 aa)
ST6GALNAC3ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. (305 aa)
FUT7Fucosyltransferase 7. (342 aa)
ST8SIA4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (359 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (422 aa)
CERS2Ceramide synthase 2. (431 aa)
ST6GALNAC4ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (302 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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