STRINGSTRING
SGCD SGCD MESP1 MESP1 NKX2-6 NKX2-6 FGF9 FGF9 BMP2 BMP2 NOG NOG TNNI3 TNNI3 LMNA LMNA HOPX HOPX BMP4 BMP4 TGFB1 TGFB1 VWA5A VWA5A PTCD2 PTCD2 MEF2C MEF2C TGFBR1 TGFBR1 TSC1 TSC1 ADRA1A ADRA1A FGFR2 FGFR2 COL11A1 COL11A1 ENG ENG GJC1 GJC1 ENSSBOP00000005807 ENSSBOP00000005807 WNT8A WNT8A S1PR1 S1PR1 OBSL1 OBSL1 POU4F1 POU4F1 SORBS2 SORBS2 ALPK2 ALPK2 ASB2 ASB2 MYH6 MYH6 WT1 WT1 MEF2A MEF2A WNT3A WNT3A WNT5A WNT5A NDRG4 NDRG4 JARID2 JARID2 PRMT1 PRMT1 ADPRHL1 ADPRHL1 SLC8A1 SLC8A1 AKAP13 AKAP13 CHD7 CHD7 ZFPM2 ZFPM2 ENSSBOP00000009522 ENSSBOP00000009522 BMPR1A BMPR1A ANKRD1 ANKRD1 MAML1 MAML1 MYL7 MYL7 TTN TTN EGLN1 EGLN1 TBX2 TBX2 EYA1 EYA1 HEY2 HEY2 TCAP TCAP CXADR CXADR ZFPM1 ZFPM1 FHOD3 FHOD3 MYL10 MYL10 HAND1 HAND1 BVES BVES NKX2-5 NKX2-5 IFRD1 IFRD1 NRG1 NRG1 SCN5A SCN5A TENM4 TENM4 TBX20 TBX20 FOXH1 FOXH1 SEMA3C SEMA3C ZIC3 ZIC3 NOTCH1 NOTCH1 RYR2 RYR2 PDGFRB PDGFRB TNNI1 TNNI1 ACVR1 ACVR1 PLEC PLEC TBX5 TBX5 BMP10 BMP10 MYH11 MYH11 WNT2 WNT2 ZMPSTE24 ZMPSTE24 VWA5B2 VWA5B2 BMP5 BMP5 SAV1 SAV1 HNRNPU HNRNPU EYA2 EYA2 CSRP3 CSRP3 C10orf113 C10orf113 MYL2 MYL2 DIPK2A DIPK2A MSC MSC CBY1 CBY1 TNNT2 TNNT2 MYLK2 MYLK2 NEBL NEBL SGCZ SGCZ SGCB SGCB HEG1 HEG1 MYO18B MYO18B GATA4 GATA4 DSG2 DSG2 SMAD7 SMAD7 FHL2 FHL2 ALPK3 ALPK3 ADAMTS9 ADAMTS9 BMP7 BMP7 PTEN PTEN TBX3 TBX3 ENSSBOP00000026153 ENSSBOP00000026153 SIRT6 SIRT6 ISL1 ISL1 IFT20 IFT20 SMAD4 SMAD4 SGCG SGCG MYH7 MYH7 ARID2 ARID2 TAZ TAZ PGM5 PGM5 MYL3 MYL3 MYBPC3 MYBPC3 TBX18 TBX18 IRX3 IRX3 ACTN2 ACTN2 VWA5B1 VWA5B1 RARB RARB TGFB2 TGFB2 KDM6B KDM6B IFRD2 IFRD2 ATG5 ATG5 NPPB NPPB LRP2 LRP2 PDLIM5 PDLIM5 NRAP NRAP CAV3 CAV3 SMAD1 SMAD1 NEB NEB PROX1 PROX1 PPP1R13L PPP1R13L XIRP2 XIRP2 ALDH1A2 ALDH1A2 MED1 MED1 HEY1 HEY1 MAP2K4 MAP2K4 SRF SRF GATA5 GATA5 EDNRA EDNRA TNNC1 TNNC1 SLC9A1 SLC9A1 TGFBR3 TGFBR3 RARA RARA MTOR MTOR PKP2 PKP2 MYOCD MYOCD DLL4 DLL4 MAPK11 MAPK11 SHOX2 SHOX2 NPPA NPPA NPRL3 NPRL3 DSP DSP CACNA1G CACNA1G GJB6 GJB6 PLN PLN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SGCDSarcoglycan delta. (290 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (273 aa)
NKX2-6NK2 homeobox 6. (301 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
TNNI3Troponin I3, cardiac type. (210 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (705 aa)
HOPXHOP homeobox. (90 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (397 aa)
VWA5AVon Willebrand factor A domain containing 5A. (785 aa)
PTCD2Pentatricopeptide repeat domain 2. (383 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
TSC1TSC complex subunit 1. (1163 aa)
ADRA1AAdrenoceptor alpha 1A. (466 aa)
FGFR2Fibroblast growth factor receptor. (839 aa)
COL11A1Collagen type XI alpha 1 chain. (1817 aa)
ENGEndoglin. (655 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (396 aa)
ENSSBOP00000005807HH_signal domain-containing protein. (115 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (336 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (379 aa)
OBSL1Obscurin like 1. (1731 aa)
POU4F1POU domain protein. (239 aa)
SORBS2Sorbin and SH3 domain containing 2. (1202 aa)
ALPK2Alpha kinase 2. (2166 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (635 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1720 aa)
WT1WT1 transcription factor. (455 aa)
MEF2AMyocyte enhancer factor 2A. (503 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (295 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
NDRG4NDRG family member 4. (421 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1247 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (395 aa)
ADPRHL1ADP-ribosylhydrolase like 1. (354 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
AKAP13A-kinase anchoring protein 13. (2783 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2996 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
ENSSBOP00000009522Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (390 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
MAML1Mastermind like transcriptional coactivator 1. (910 aa)
MYL7Myosin light chain 7. (192 aa)
TTNUncharacterized protein. (27115 aa)
EGLN1Fe2OG dioxygenase domain-containing protein. (128 aa)
TBX2T-box transcription factor 2. (633 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
TCAPTitin-cap. (167 aa)
CXADRCXADR Ig-like cell adhesion molecule. (363 aa)
ZFPM1Uncharacterized protein. (146 aa)
FHOD3Formin homology 2 domain containing 3. (1568 aa)
MYL10Myosin light chain 10. (230 aa)
HAND1Heart and neural crest derivatives expressed 1. (225 aa)
BVESBlood vessel epicardial substance. (357 aa)
NKX2-5NK2 homeobox 5. (316 aa)
IFRD1Interferon related developmental regulator 1. (451 aa)
NRG1Neuregulin 1. (713 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa)
TENM4Teneurin transmembrane protein 4. (2864 aa)
TBX20T-box transcription factor 20. (446 aa)
FOXH1Forkhead box H1. (395 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
ZIC3Zic family member 3. (467 aa)
NOTCH1Notch receptor 1. (2538 aa)
RYR2Ryanodine receptor 2. (4909 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1108 aa)
TNNI1Troponin I1, slow skeletal type. (187 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
PLECPlectin. (4573 aa)
TBX5T-box transcription factor 5. (518 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1996 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (321 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (479 aa)
VWA5B2Von Willebrand factor A domain containing 5B2. (1113 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (602 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (507 aa)
CSRP3Cysteine and glycine rich protein 3. (237 aa)
C10orf113Chromosome 10 open reading frame 113. (134 aa)
MYL2Myosin light chain 2. (165 aa)
DIPK2ADivergent protein kinase domain 2A. (430 aa)
MSCMusculin. (206 aa)
CBY1Chibby family member 1, beta catenin antagonist. (169 aa)
TNNT2Troponin T2, cardiac type. (298 aa)
MYLK2Myosin light chain kinase 2. (596 aa)
NEBLNebulette. (888 aa)
SGCZSarcoglycan zeta. (312 aa)
SGCBSarcoglycan beta. (316 aa)
HEG1Heart development protein with EGF like domains 1. (1144 aa)
MYO18BMyosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2567 aa)
GATA4GATA binding protein 4. (443 aa)
DSG2Desmoglein 2. (1118 aa)
SMAD7Mothers against decapentaplegic homolog. (492 aa)
FHL2Four and a half LIM domains 2. (370 aa)
ALPK3Alpha kinase 3. (1869 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1935 aa)
BMP7Bone morphogenetic protein 7. (430 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
TBX3T-box transcription factor 3. (743 aa)
ENSSBOP00000026153Uncharacterized protein. (70 aa)
SIRT6Sirtuin 6. (355 aa)
ISL1ISL LIM homeobox 1. (349 aa)
IFT20Intraflagellar transport 20. (158 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SGCGSarcoglycan gamma. (309 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1716 aa)
ARID2AT-rich interaction domain 2. (1827 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (293 aa)
PGM5Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (567 aa)
MYL3Myosin light chain 3. (197 aa)
MYBPC3Myosin binding protein C, cardiac. (1274 aa)
TBX18T-box transcription factor 18. (607 aa)
IRX3Iroquois homeobox 3. (440 aa)
ACTN2Actinin alpha 2. (791 aa)
VWA5B1Von Willebrand factor A domain containing 5B1. (1233 aa)
RARBRetinoic acid receptor beta. (448 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
KDM6BLysine demethylase 6B. (1681 aa)
IFRD2Interferon related developmental regulator 2. (510 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
NPPBNatriuretic peptide B. (135 aa)
LRP2LDL receptor related protein 2. (4618 aa)
PDLIM5PDZ and LIM domain 5. (625 aa)
NRAPNebulin related anchoring protein. (1735 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
NEBNebulin. (7391 aa)
PROX1Prospero homeobox 1. (737 aa)
PPP1R13LANK_REP_REGION domain-containing protein. (358 aa)
XIRP2Xin actin binding repeat containing 2. (3546 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1543 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (406 aa)
SRFSerum response factor. (435 aa)
GATA5GATA binding protein 5. (299 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
TGFBR3Transforming growth factor beta receptor 3. (914 aa)
RARARetinoic acid receptor alpha. (465 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
PKP2Plakophilin 2. (840 aa)
MYOCDMyocardin. (986 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (696 aa)
MAPK11Mitogen-activated protein kinase. (372 aa)
SHOX2Short stature homeobox 2. (305 aa)
NPPANatriuretic peptide A. (153 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (582 aa)
DSPDesmoplakin. (2874 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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