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| | ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (350 aa) |
| | CERS1 | TLC domain-containing protein. (239 aa) |
| | DEGS2 | Delta 4-desaturase, sphingolipid 2. (323 aa) |
| | ST6GALNAC6 | Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (299 aa) |
| | ELOVL6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | PEMT | Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. (236 aa) |
| | ENSSBOP00000000783 | Uncharacterized protein. (129 aa) |
| | HACD4 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (232 aa) |
| | SPHK1 | Sphingosine kinase 1. (488 aa) |
| | B4GALT5 | Beta-1,4-galactosyltransferase 5. (368 aa) |
| | SGPP2 | Sphingosine-1-phosphate phosphatase 2. (353 aa) |
| | FUT9 | Fucosyltransferase 9. (359 aa) |
| | HACD2 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (254 aa) |
| | ENSSBOP00000004284 | Uncharacterized protein. (92 aa) |
| | SPTSSB | Serine palmitoyltransferase small subunit B. (76 aa) |
| | AGK | Acylglycerol kinase. (421 aa) |
| | UGCG | UDP-glucose ceramide glucosyltransferase. (297 aa) |
| | FUT4 | Fucosyltransferase 4. (343 aa) |
| | OSBP | Oxysterol-binding protein; Belongs to the OSBP family. (724 aa) |
| | PNPLA1 | Patatin like phospholipase domain containing 1. (520 aa) |
| | CLN8 | CLN8 transmembrane ER and ERGIC protein. (286 aa) |
| | PLPP1 | Phospholipid phosphatase 1. (284 aa) |
| | PPAP2B | acidPPc domain-containing protein. (311 aa) |
| | B4GALT4 | Beta-1,4-galactosyltransferase 4. (344 aa) |
| | CERKL | Ceramide kinase like. (542 aa) |
| | ALDH3B1 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa) |
| | ENSSBOP00000010565 | Uncharacterized protein. (106 aa) |
| | ORMDL3 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | KDSR | 3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa) |
| | ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. (448 aa) |
| | ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (340 aa) |
| | C20orf173 | Chromosome 20 open reading frame 173; Belongs to the glycosyltransferase 29 family. (194 aa) |
| | ALDH3B2 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (497 aa) |
| | ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (375 aa) |
| | TMEM130 | Transmembrane protein 130. (358 aa) |
| | CERS4 | Ceramide synthase 4. (400 aa) |
| | PPM1L | Protein phosphatase, Mg2+/Mn2+ dependent 1L. (360 aa) |
| | TLCD3B | TLC domain containing 3B. (274 aa) |
| | ACER3 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (225 aa) |
| | SGMS1 | Sphingomyelin synthase 1. (413 aa) |
| | ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5; Belongs to the glycosyltransferase 29 family. (412 aa) |
| | CERS3 | Ceramide synthase 3. (382 aa) |
| | A3GALT2 | Alpha 1,3-galactosyltransferase 2. (339 aa) |
| | ABCA2 | ATP binding cassette subfamily A member 2. (2353 aa) |
| | P2RX1 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa) |
| | LARGE1 | LARGE xylosyl- and glucuronyltransferase 1. (756 aa) |
| | SAMD8 | Sterile alpha motif domain containing 8. (500 aa) |
| | SGMS2 | Sphingomyelin synthase 2. (365 aa) |
| | ENSSBOP00000018609 | Uncharacterized protein. (94 aa) |
| | ALOX12B | Arachidonate 12-lipoxygenase, 12R type. (701 aa) |
| | SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa) |
| | CYP4F22 | Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family. (571 aa) |
| | CERS6 | Ceramide synthase 6. (375 aa) |
| | SPTLC1 | Aminotran_1_2 domain-containing protein. (498 aa) |
| | ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6; Belongs to the glycosyltransferase 29 family. (400 aa) |
| | PRKD3 | Protein kinase D3. (758 aa) |
| | B4GALNT1 | Beta-1,4 N-acetylgalactosaminyltransferase. (533 aa) |
| | ACER1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa) |
| | ELOVL3 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa) |
| | SPTLC3 | Serine palmitoyltransferase long chain base subunit 3. (553 aa) |
| | SPTLC2 | Serine palmitoyltransferase long chain base subunit 2. (497 aa) |
| | UGT8 | UDP glycosyltransferase 8; Belongs to the UDP-glycosyltransferase family. (541 aa) |
| | ASAH1 | N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (432 aa) |
| | DEGS1 | Delta 4-desaturase, sphingolipid 1. (323 aa) |
| | FA2H | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa) |
| | ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. (380 aa) |
| | ST6GALNAC5 | ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; Belongs to the glycosyltransferase 29 family. (351 aa) |
| | SPHK2 | Sphingosine kinase 2. (656 aa) |
| | ASAH2 | Neutral ceramidase. (778 aa) |
| | ELOVL7 | Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa) |
| | B4GALT3 | Beta-1,4-galactosyltransferase 3. (393 aa) |
| | ACER2 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa) |
| | ORMDL1 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | ST6GALNAC4 | ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (302 aa) |
| | CERS2 | Ceramide synthase 2. (431 aa) |
| | SMPD2 | Sphingomyelin phosphodiesterase 2. (422 aa) |
| | ELOVL2 | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (297 aa) |
| | ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (359 aa) |
| | SGPP1 | Sphingosine-1-phosphate phosphatase 1. (372 aa) |
| | ST6GALNAC3 | ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. (305 aa) |
| | CERS5 | Ceramide synthase 5. (426 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | B4GALT6 | Beta-1,4-galactosyltransferase 6. (382 aa) |
| | ABCA8 | ATP binding cassette subfamily A member 8. (1621 aa) |
| | PRKD2 | Protein kinase D2. (788 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (824 aa) |
| | SPTSSA | Serine palmitoyltransferase small subunit A. (71 aa) |
| | TM9SF2 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (663 aa) |
| | GAL3ST1 | Galactose-3-O-sulfotransferase 1. (482 aa) |
| | ELOVL1 | Elongation of very long chain fatty acids protein. (286 aa) |
| | B3GALT2 | Hexosyltransferase. (422 aa) |
