(9 nodes) Intestinal cholesterol absorption network (Saimiri boliviensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CEL	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (643 aa)
	NPC1	NPC intracellular cholesterol transporter 1. (1278 aa)
	SOAT2	O-acyltransferase. (526 aa)
	ABCG5	ATP binding cassette subfamily G member 5. (651 aa)
	LDLR	Low density lipoprotein receptor. (569 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (472 aa)
	ABCG8	ATP binding cassette subfamily G member 8. (672 aa)
	LIMA1	LIM domain and actin binding 1. (761 aa)
	NPC1L1	NPC1 like intracellular cholesterol transporter 1. (1237 aa)

Your Current Organism:

Saimiri boliviensis

NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCG5	ABCG8	ENSSBOP00000027425	ENSSBOP00000003173	ATP binding cassette subfamily G member 5.	ATP binding cassette subfamily G member 8.	0.999
ABCG5	NPC1	ENSSBOP00000027425	ENSSBOP00000032598	ATP binding cassette subfamily G member 5.	NPC intracellular cholesterol transporter 1.	0.415
ABCG5	NPC1L1	ENSSBOP00000027425	ENSSBOP00000031302	ATP binding cassette subfamily G member 5.	NPC1 like intracellular cholesterol transporter 1.	0.757
ABCG5	SOAT2	ENSSBOP00000027425	ENSSBOP00000037594	ATP binding cassette subfamily G member 5.	O-acyltransferase.	0.424
ABCG8	ABCG5	ENSSBOP00000003173	ENSSBOP00000027425	ATP binding cassette subfamily G member 8.	ATP binding cassette subfamily G member 5.	0.999
ABCG8	NPC1L1	ENSSBOP00000003173	ENSSBOP00000031302	ATP binding cassette subfamily G member 8.	NPC1 like intracellular cholesterol transporter 1.	0.729
NPC1	ABCG5	ENSSBOP00000032598	ENSSBOP00000027425	NPC intracellular cholesterol transporter 1.	ATP binding cassette subfamily G member 5.	0.415
NPC1L1	ABCG5	ENSSBOP00000031302	ENSSBOP00000027425	NPC1 like intracellular cholesterol transporter 1.	ATP binding cassette subfamily G member 5.	0.757
NPC1L1	ABCG8	ENSSBOP00000031302	ENSSBOP00000003173	NPC1 like intracellular cholesterol transporter 1.	ATP binding cassette subfamily G member 8.	0.729
NPC1L1	SOAT2	ENSSBOP00000031302	ENSSBOP00000037594	NPC1 like intracellular cholesterol transporter 1.	O-acyltransferase.	0.427
SOAT2	ABCG5	ENSSBOP00000037594	ENSSBOP00000027425	O-acyltransferase.	ATP binding cassette subfamily G member 5.	0.424
SOAT2	NPC1L1	ENSSBOP00000037594	ENSSBOP00000031302	O-acyltransferase.	NPC1 like intracellular cholesterol transporter 1.	0.427