STRINGSTRING
FAIM2 FAIM2 SSTR3 SSTR3 NOG NOG SCRIB SCRIB B4GALT2 B4GALT2 ENSSBOP00000001789 ENSSBOP00000001789 ENSSBOP00000002040 ENSSBOP00000002040 NAGLU NAGLU GNPAT GNPAT NHLH2 NHLH2 NEUROD1 NEUROD1 CDK5 CDK5 TTLL1 TTLL1 NEUROD2 NEUROD2 RORA RORA PHOX2A PHOX2A ENSSBOP00000005799 ENSSBOP00000005799 ENSSBOP00000005807 ENSSBOP00000005807 KLHL1 KLHL1 ATRN ATRN POU4F1 POU4F1 MTPN MTPN ENSSBOP00000007753 ENSSBOP00000007753 PHOX2B PHOX2B EPHB2 EPHB2 EPHB1 EPHB1 DLC1 DLC1 PDSS2 PDSS2 CDK5R1 CDK5R1 IGF1R IGF1R AARS1 AARS1 ATP7A ATP7A ATF5 ATF5 KLHL4 KLHL4 HSPA5 HSPA5 KAT2A KAT2A DIXDC1 DIXDC1 WNT7A WNT7A ENSSBOP00000013998 ENSSBOP00000013998 FAM205A FAM205A WNT1 WNT1 GLI1 GLI1 OPHN1 OPHN1 HOXA2 HOXA2 CTNNA2 CTNNA2 SCN5A SCN5A CEP290 CEP290 ATP1B2 ATP1B2 EGR2 EGR2 DLL1 DLL1 SLC25A46 SLC25A46 MECP2 MECP2 HOXB2 HOXB2 LHX1 LHX1 ATF2 ATF2 CRKL CRKL KNDC1 KNDC1 LPAR1 LPAR1 PTF1A PTF1A KLHL5 KLHL5 EZH2 EZH2 KDM2B KDM2B BMP5 BMP5 SEMA4C SEMA4C FZD4 FZD4 ENSSBOP00000020558 ENSSBOP00000020558 NRXN1 NRXN1 PSMG1 PSMG1 AGTPBP1 AGTPBP1 CDK5R2 CDK5R2 COQ8B COQ8B GART GART CKB CKB SEZ6 SEZ6 ARL13B ARL13B ENSSBOP00000023313 ENSSBOP00000023313 CBLN1 CBLN1 LEF1 LEF1 RERE RERE PTBP2 PTBP2 WHRN WHRN CTNNB1 CTNNB1 BMP7 BMP7 LDB1 LDB1 ENSSBOP00000026088 ENSSBOP00000026088 ABL1 ABL1 CNTN1 CNTN1 RPGRIP1L RPGRIP1L LHX5 LHX5 TBR1 TBR1 KIF14 KIF14 OTX1 OTX1 SPTBN2 SPTBN2 LMX1A LMX1A UQCRQ UQCRQ ZNF365 ZNF365 BCL2 BCL2 ENSSBOP00000030810 ENSSBOP00000030810 NAV2 NAV2 SEC24B SEC24B CD3E CD3E NFIB NFIB HERC1 HERC1 PTPRS PTPRS CLP1 CLP1 SMAD1 SMAD1 PROX1 PROX1 OGDH OGDH HNRNPD HNRNPD ENSSBOP00000033458 ENSSBOP00000033458 TTBK2 TTBK2 GATA2 GATA2 PLXNA2 PLXNA2 CRK CRK ALDH1A2 ALDH1A2 GDF10 GDF10 ENSSBOP00000035139 ENSSBOP00000035139 EGF EGF NCSTN NCSTN SMO SMO HOXB1 HOXB1 SEZ6L2 SEZ6L2 AHI1 AHI1 GRID2 GRID2 GLI2 GLI2 CPLANE1 CPLANE1 LRRC1 LRRC1 TTC21B TTC21B ABAT ABAT SERPINE2 SERPINE2 MYO16 MYO16
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FAIM2Fas apoptotic inhibitory molecule 2; Belongs to the BI1 family. (316 aa)
SSTR3Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (418 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SCRIBScribble planar cell polarity protein. (1655 aa)
B4GALT2Beta-1,4-galactosyltransferase 2. (369 aa)
ENSSBOP00000001789Uncharacterized protein. (192 aa)
ENSSBOP00000002040Uncharacterized protein. (404 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (630 aa)
GNPATDihydroxyacetone phosphate acyltransferase. (680 aa)
NHLH2Nescient helix-loop-helix 2. (188 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
TTLL1Tubulin tyrosine ligase like 1. (423 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
RORARAR related orphan receptor A. (549 aa)
PHOX2APaired like homeobox 2A. (234 aa)
ENSSBOP00000005799Uncharacterized protein. (285 aa)
ENSSBOP00000005807HH_signal domain-containing protein. (115 aa)
KLHL1Kelch like family member 1. (687 aa)
ATRNAttractin. (1260 aa)
POU4F1POU domain protein. (239 aa)
MTPNMyotrophin. (118 aa)
ENSSBOP00000007753G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (319 aa)
PHOX2BHomeobox domain-containing protein. (184 aa)
EPHB2EPH receptor B2. (1088 aa)
EPHB1EPH receptor B1. (984 aa)
DLC1DLC1 Rho GTPase activating protein. (1526 aa)
PDSS2Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family. (342 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
IGF1RTyrosine-protein kinase receptor. (1366 aa)
AARS1Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (968 aa)
ATP7AATPase copper transporting alpha. (1500 aa)
ATF5Activating transcription factor 5. (288 aa)
KLHL4Kelch like family member 4. (719 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
DIXDC1DIX domain containing 1. (683 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
ENSSBOP00000013998Uncharacterized protein. (241 aa)
FAM205AFamily with sequence similarity 205 member A. (1334 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
GLI1GLI family zinc finger 1. (1106 aa)
OPHN1Oligophrenin 1. (802 aa)
HOXA2Homeobox A2. (372 aa)
CTNNA2Catenin alpha 2. (953 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa)
CEP290Centrosomal protein 290. (2478 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
EGR2Early growth response 2. (473 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
SLC25A46Solute carrier family 25 member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (418 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (493 aa)
HOXB2Homeobox B2. (353 aa)
LHX1LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity). (438 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (507 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
KNDC1Kinase non-catalytic C-lobe domain containing 1. (1712 aa)
LPAR1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (365 aa)
PTF1APancreas associated transcription factor 1a. (261 aa)
KLHL5Kelch like family member 5. (754 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
KDM2BLysine demethylase 2B. (1336 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (820 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (539 aa)
ENSSBOP00000020558Uncharacterized protein. (130 aa)
NRXN1Neurexin 1. (1507 aa)
PSMG1Proteasome assembly chaperone 1; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2. (288 aa)
AGTPBP1ATP/GTP binding protein 1. (1242 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (301 aa)
COQ8BCoenzyme Q8B. (590 aa)
GARTTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1059 aa)
CKBUncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
SEZ6Seizure related 6 homolog. (975 aa)
ARL13BADP ribosylation factor like GTPase 13B. (428 aa)
ENSSBOP00000023313Protein kinase domain-containing protein. (248 aa)
CBLN1Cerebellin 1 precursor. (184 aa)
LEF1Lymphoid enhancer binding factor 1. (328 aa)
REREArginine-glutamic acid dipeptide repeats. (1535 aa)
PTBP2Polypyrimidine tract binding protein 2. (534 aa)
WHRNWhirlin. (892 aa)
CTNNB1Catenin beta 1. (781 aa)
BMP7Bone morphogenetic protein 7. (430 aa)
LDB1LIM domain binding 1. (409 aa)
ENSSBOP00000026088HECT domain-containing protein. (244 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
CNTN1Contactin 1. (1018 aa)
RPGRIP1LRPGRIP1 like. (1269 aa)
LHX5LIM homeobox 5. (402 aa)
TBR1T-box brain transcription factor 1. (682 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1652 aa)
OTX1Orthodenticle homeobox 1. (355 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2345 aa)
LMX1ALIM homeobox transcription factor 1 alpha. (382 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
ZNF365Zinc finger protein 365. (407 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ENSSBOP00000030810Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (358 aa)
NAV2Neuron navigator 2. (2429 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1274 aa)
CD3ECD3e molecule. (198 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (561 aa)
HERC1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (4860 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1819 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
PROX1Prospero homeobox 1. (737 aa)
OGDHOxoglutarate dehydrogenase. (1038 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D. (355 aa)
ENSSBOP00000033458Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
TTBK2Tau tubulin kinase 2. (1243 aa)
GATA2GATA binding protein 2. (480 aa)
PLXNA2Plexin A2. (1909 aa)
CRKCRK proto-oncogene, adaptor protein. (249 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (405 aa)
ENSSBOP00000035139Uncharacterized protein. (126 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1186 aa)
NCSTNNicastrin. (716 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (775 aa)
HOXB1Homeobox B1. (300 aa)
SEZ6L2Seizure related 6 homolog like 2. (923 aa)
AHI1Abelson helper integration site 1. (1157 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
GLI2GLI family zinc finger 2. (1564 aa)
CPLANE1Ciliogenesis and planar polarity effector 1. (3135 aa)
LRRC1Leucine rich repeat containing 1. (443 aa)
TTC21BTetratricopeptide repeat domain 21B. (1320 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (516 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
MYO16Myosin XVI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1814 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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