(14 nodes) Retromer complex network (Saimiri boliviensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSBOP00000015324	Metallophos_2 domain-containing protein. (79 aa)
	SNX1	Sorting nexin 1. (538 aa)
	TBC1D5	TBC1 domain family member 5. (816 aa)
	VPS29	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (225 aa)
	SNX5	Sorting nexin; Involved in several stages of intracellular trafficking. (404 aa)
	ENSSBOP00000012709	PX domain-containing protein. (339 aa)
	VPS35	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (797 aa)
	SNX2	Sorting nexin 2. (523 aa)
	SNX3	Sorting nexin 3. (162 aa)
	VPS26B	VPS26, retromer complex component B. (336 aa)
	VPS26A	VPS26, retromer complex component A. (327 aa)
	ENSSBOP00000030187	Uncharacterized protein. (240 aa)
	DENND4C	DENN domain containing 4C. (1958 aa)
	SNX12	Sorting nexin 12. (168 aa)

Your Current Organism:

Saimiri boliviensis

NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSBOP00000012709	ENSSBOP00000015324	ENSSBOP00000012709	ENSSBOP00000015324	PX domain-containing protein.	Metallophos_2 domain-containing protein.	0.623
ENSSBOP00000012709	SNX1	ENSSBOP00000012709	ENSSBOP00000000143	PX domain-containing protein.	Sorting nexin 1.	0.800
ENSSBOP00000012709	SNX2	ENSSBOP00000012709	ENSSBOP00000014094	PX domain-containing protein.	Sorting nexin 2.	0.834
ENSSBOP00000012709	VPS26A	ENSSBOP00000012709	ENSSBOP00000027290	PX domain-containing protein.	VPS26, retromer complex component A.	0.427
ENSSBOP00000012709	VPS26B	ENSSBOP00000012709	ENSSBOP00000026004	PX domain-containing protein.	VPS26, retromer complex component B.	0.416
ENSSBOP00000012709	VPS29	ENSSBOP00000012709	ENSSBOP00000008488	PX domain-containing protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.623
ENSSBOP00000012709	VPS35	ENSSBOP00000012709	ENSSBOP00000013949	PX domain-containing protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.643
ENSSBOP00000015324	ENSSBOP00000012709	ENSSBOP00000015324	ENSSBOP00000012709	Metallophos_2 domain-containing protein.	PX domain-containing protein.	0.623
ENSSBOP00000015324	ENSSBOP00000030187	ENSSBOP00000015324	ENSSBOP00000030187	Metallophos_2 domain-containing protein.	Uncharacterized protein.	0.623
ENSSBOP00000015324	SNX1	ENSSBOP00000015324	ENSSBOP00000000143	Metallophos_2 domain-containing protein.	Sorting nexin 1.	0.943
ENSSBOP00000015324	SNX12	ENSSBOP00000015324	ENSSBOP00000035378	Metallophos_2 domain-containing protein.	Sorting nexin 12.	0.728
ENSSBOP00000015324	SNX2	ENSSBOP00000015324	ENSSBOP00000014094	Metallophos_2 domain-containing protein.	Sorting nexin 2.	0.947
ENSSBOP00000015324	SNX3	ENSSBOP00000015324	ENSSBOP00000024259	Metallophos_2 domain-containing protein.	Sorting nexin 3.	0.843
ENSSBOP00000015324	SNX5	ENSSBOP00000015324	ENSSBOP00000011164	Metallophos_2 domain-containing protein.	Sorting nexin; Involved in several stages of intracellular trafficking.	0.748
ENSSBOP00000015324	TBC1D5	ENSSBOP00000015324	ENSSBOP00000004660	Metallophos_2 domain-containing protein.	TBC1 domain family member 5.	0.928
ENSSBOP00000015324	VPS26A	ENSSBOP00000015324	ENSSBOP00000027290	Metallophos_2 domain-containing protein.	VPS26, retromer complex component A.	0.971
ENSSBOP00000015324	VPS26B	ENSSBOP00000015324	ENSSBOP00000026004	Metallophos_2 domain-containing protein.	VPS26, retromer complex component B.	0.960
ENSSBOP00000015324	VPS35	ENSSBOP00000015324	ENSSBOP00000013949	Metallophos_2 domain-containing protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.992
ENSSBOP00000030187	ENSSBOP00000015324	ENSSBOP00000030187	ENSSBOP00000015324	Uncharacterized protein.	Metallophos_2 domain-containing protein.	0.623
ENSSBOP00000030187	SNX1	ENSSBOP00000030187	ENSSBOP00000000143	Uncharacterized protein.	Sorting nexin 1.	0.800