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| | UBXN11 | UBX domain protein 11. (504 aa) |
| | ARMC9 | Armadillo repeat containing 9. (776 aa) |
| | RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa) |
| | CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (392 aa) |
| | USP25 | Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family. (1110 aa) |
| | TOM1L1 | Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family. (476 aa) |
| | UBXN7 | UBX domain-containing protein 7. (456 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa) |
| | PML | Promyelocytic leukemia. (806 aa) |
| | DNAJB2 | DnaJ heat shock protein family (Hsp40) member B2. (324 aa) |
| | TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1474 aa) |
| | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (692 aa) |
| | CASP8AP2 | Caspase 8 associated protein 2. (1946 aa) |
| | CUEDC1 | CUE domain containing 1. (334 aa) |
| | TRIM32 | Tripartite motif containing 32. (653 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa) |
| | N4BP1 | NEDD4 binding protein 1. (810 aa) |
| | TDG | Thymine DNA glycosylase. (410 aa) |
| | OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1. (282 aa) |
| | SPRTN | SprT-like N-terminal domain. (487 aa) |
| | USP5 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (864 aa) |
| | ENSSBOP00000006391 | Uncharacterized protein. (1054 aa) |
| | HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4521 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa) |
| | UEVLD | UEV and lactate/malate dehyrogenase domains. (518 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | MARK4 | Non-specific serine/threonine protein kinase. (736 aa) |
| | JARID2 | Jumonji and AT-rich interaction domain containing 2. (1247 aa) |
| | RNFT1 | Ring finger protein, transmembrane 1. (398 aa) |
| | UBE2L6 | Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) |
| | ENSSBOP00000010240 | Uncharacterized protein. (349 aa) |
| | NEDD4 | NEDD4 E3 ubiquitin protein ligase. (1319 aa) |
| | VPS28 | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (221 aa) |
| | ENSSBOP00000011397 | Uncharacterized protein. (111 aa) |
| | ENSSBOP00000011417 | Uncharacterized protein. (138 aa) |
| | SHARPIN | SHANK associated RH domain interactor. (386 aa) |
| | UCHL3 | Ubiquitin carboxyl-terminal hydrolase. (230 aa) |
| | N4BP2 | NEDD4 binding protein 2. (1770 aa) |
| | RAD23A | RAD23 homolog A, nucleotide excision repair protein. (365 aa) |
| | ENSSBOP00000013088 | Uncharacterized protein. (164 aa) |
| | HDAC6 | Histone deacetylase 6. (1244 aa) |
| | UBXN2A | UBX domain protein 2A. (260 aa) |
| | ENSSBOP00000014262 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (86 aa) |
| | TOM1 | Target of myb1 membrane trafficking protein; Belongs to the TOM1 family. (459 aa) |
| | RAD23B | Uncharacterized protein. (409 aa) |
| | SQSTM1 | Sequestosome 1. (439 aa) |
| | GGA2 | Golgi associated, gamma adaptin ear containing, ARF binding protein 2. (604 aa) |
| | SIMC1 | SUMO interacting motifs containing 1. (843 aa) |
| | UBR5 | Ubiquitin protein ligase E3 component n-recognin 5. (2799 aa) |
| | UBAP1 | Ubiquitin associated protein 1. (494 aa) |
| | AMFR | Autocrine motility factor receptor. (643 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | BUB3 | BUB3 mitotic checkpoint protein. (328 aa) |
| | N4BP2L1 | NEDD4 binding protein 2 like 1. (201 aa) |
| | UBXN2B | UBX domain protein 2B. (331 aa) |
| | ILRUN | Inflammation and lipid regulator with UBA-like and NBR1-like domains. (224 aa) |
| | ADRM1 | Adhesion regulating molecule 1. (407 aa) |
| | CBX7 | Chromobox 7. (251 aa) |
| | ZFAND2B | Zinc finger AN1-type containing 2B. (257 aa) |
| | STAM | Signal transducing adaptor molecule. (541 aa) |
| | ENSSBOP00000019963 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa) |
| | USP13 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (826 aa) |
| | VPS36 | Vacuolar protein sorting 36 homolog. (462 aa) |
| | UBAP1L | Ubiquitin associated protein 1 like. (400 aa) |
| | RNF185 | Ring finger protein 185. (192 aa) |
| | AUP1 | AUP1 lipid droplet regulating VLDL assembly factor. (410 aa) |
| | NBR1 | NBR1 autophagy cargo receptor. (966 aa) |
| | MARCHF7 | Membrane associated ring-CH-type finger 7. (703 aa) |
| | STAM2 | Uncharacterized protein. (525 aa) |
| | ENSSBOP00000021788 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (80 aa) |
| | CCDC197 | Coiled-coil domain containing 197. (271 aa) |
| | ENSSBOP00000022506 | Uncharacterized protein. (442 aa) |
| | USPL1 | Ubiquitin specific peptidase like 1. (1091 aa) |
| | DCUN1D1 | DCN1-like protein. (244 aa) |
| | UBXN8 | UBX domain protein 8. (205 aa) |
| | ENSSBOP00000024039 | SprT-like domain-containing protein. (580 aa) |
| | DCUN1D2 | DCN1-like protein. (259 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (706 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (441 aa) |
| | ENSSBOP00000025764 | Ubiquitin carboxyl-terminal hydrolase. (178 aa) |
| | FBXW9 | F-box and WD repeat domain containing 9. (478 aa) |
| | GGA3 | Golgi associated, gamma adaptin ear containing, ARF binding protein 3. (722 aa) |
| | ENSSBOP00000026884 | DCN1-like protein. (97 aa) |
| | TOLLIP | Toll interacting protein. (242 aa) |
| | ASCC2 | Activating signal cointegrator 1 complex subunit 2. (703 aa) |
| | MVB12A | Multivesicular body subunit 12A. (273 aa) |
| | CBX4 | Chromobox 4. (507 aa) |
| | DCUN1D4 | DCN1-like protein. (302 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (59 aa) |
| | USP16 | Ubiquitinyl hydrolase 1. (326 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | RNF4 | Ring finger protein 4. (190 aa) |
| | TEPSIN | TEPSIN adaptor related protein complex 4 accessory protein. (587 aa) |
| | ENSSBOP00000029848 | Uncharacterized protein. (141 aa) |
| | SOBP | Sine oculis binding protein homolog. (720 aa) |
| | TOM1L2 | Target of myb1 like 2 membrane trafficking protein; Belongs to the TOM1 family. (536 aa) |
| | HABP4 | Hyaluronan binding protein 4. (338 aa) |
| | OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2. (233 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (570 aa) |
| | SMARCAD1 | Uncharacterized protein. (1026 aa) |
| | ENSSBOP00000032023 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (609 aa) |
| | HSPB1 | Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (203 aa) |
| | PLAA | Phospholipase A2 activating protein. (768 aa) |
| | TSG101 | Tumor susceptibility 101. (392 aa) |
| | CUEDC2 | CUE domain containing 2. (290 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (440 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (615 aa) |
| | GGA1 | Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (639 aa) |
| | SERBP1 | SERPINE1 mRNA binding protein 1. (393 aa) |
| | FBXO7 | F-box protein 7. (514 aa) |
| | TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (191 aa) |
| | WDR92 | WD repeat domain 92. (357 aa) |
| | UBXN1 | UBX domain protein 1. (447 aa) |
| | RNF19B | Ring finger protein 19B. (436 aa) |
| | ENSSBOP00000038827 | Uncharacterized protein. (289 aa) |
| | FAF2 | Fas associated factor family member 2. (438 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (791 aa) |
| | FAF1 | Fas associated factor 1. (652 aa) |
| | NPLOC4 | NPL4 homolog, ubiquitin recognition factor. (539 aa) |
| | ATPAF1 | ATP synthase mitochondrial F1 complex assembly factor 1. (351 aa) |
| | RNF31 | Uncharacterized protein. (1072 aa) |
