(4 nodes) Mitotic checkpoint complex network (Saimiri boliviensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSBOP00000023587	WD_REPEATS_REGION domain-containing protein. (467 aa)
	BUB1B	BUB1 N-terminal domain-containing protein. (1050 aa)
	CDC20	WD_REPEATS_REGION domain-containing protein. (520 aa)
	MAD2L1	Mitotic arrest deficient 2 like 1. (205 aa)

Your Current Organism:

Saimiri boliviensis

NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BUB1B	CDC20	ENSSBOP00000009355	ENSSBOP00000033737	BUB1 N-terminal domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.989
BUB1B	ENSSBOP00000023587	ENSSBOP00000009355	ENSSBOP00000023587	BUB1 N-terminal domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.989
BUB1B	MAD2L1	ENSSBOP00000009355	ENSSBOP00000030235	BUB1 N-terminal domain-containing protein.	Mitotic arrest deficient 2 like 1.	0.999
CDC20	BUB1B	ENSSBOP00000033737	ENSSBOP00000009355	WD_REPEATS_REGION domain-containing protein.	BUB1 N-terminal domain-containing protein.	0.989
CDC20	MAD2L1	ENSSBOP00000033737	ENSSBOP00000030235	WD_REPEATS_REGION domain-containing protein.	Mitotic arrest deficient 2 like 1.	0.998
ENSSBOP00000023587	BUB1B	ENSSBOP00000023587	ENSSBOP00000009355	WD_REPEATS_REGION domain-containing protein.	BUB1 N-terminal domain-containing protein.	0.989
ENSSBOP00000023587	MAD2L1	ENSSBOP00000023587	ENSSBOP00000030235	WD_REPEATS_REGION domain-containing protein.	Mitotic arrest deficient 2 like 1.	0.982
MAD2L1	BUB1B	ENSSBOP00000030235	ENSSBOP00000009355	Mitotic arrest deficient 2 like 1.	BUB1 N-terminal domain-containing protein.	0.999
MAD2L1	CDC20	ENSSBOP00000030235	ENSSBOP00000033737	Mitotic arrest deficient 2 like 1.	WD_REPEATS_REGION domain-containing protein.	0.998
MAD2L1	ENSSBOP00000023587	ENSSBOP00000030235	ENSSBOP00000023587	Mitotic arrest deficient 2 like 1.	WD_REPEATS_REGION domain-containing protein.	0.982