49 items (Saimiri boliviensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSBOP00000018470	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (117 aa)
	LCMT1	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (334 aa)
	ICMT	Protein-S-isoprenylcysteine O-methyltransferase. (278 aa)
	MAP3K12	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa)
	WIPI2	Uncharacterized protein. (430 aa)
	SIRT2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
	SENP8	SUMO peptidase family member, NEDD8 specific. (212 aa)
	RNF7	Ring finger protein 7. (113 aa)
	UBE2F	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (185 aa)
	ENSSBOP00000009748	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (174 aa)
	RPS6KA5	Ribosomal protein S6 kinase. (805 aa)
	DCAF1	DDB1 and CUL4 associated factor 1. (1507 aa)
	UCHL3	Ubiquitin carboxyl-terminal hydrolase. (230 aa)
	ESCO2	Establishment of sister chromatid cohesion N-acetyltransferase 2. (511 aa)
	RBX1	Ring-box 1. (105 aa)
	RHBDD1	Rhomboid domain containing 1. (315 aa)
	ENSSBOP00000032697	UBIQUITIN_CONJUGAT_2 domain-containing protein. (143 aa)
	RPS6KA4	Ribosomal protein S6 kinase. (805 aa)
	AGBL4	ATP/GTP binding protein like 4. (503 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	SUMF1	Sulfatase modifying factor 1. (376 aa)
	FOLH1	Folate hydrolase 1. (750 aa)
	PKN1	Protein kinase N1. (951 aa)
	HLCS	Holocarboxylase synthetase. (728 aa)
	PRKCD	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (720 aa)
	AURKB	Aurora kinase B; Belongs to the protein kinase superfamily. (352 aa)
	ENSSBOP00000014796	Uncharacterized protein. (208 aa)
	ATG16L1	Autophagy related 16 like 1. (624 aa)
	ATG7	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (733 aa)
	FN3KRP	Fructosamine 3 kinase related protein; Belongs to the fructosamine kinase family. (287 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
	TTL	Uncharacterized protein. (423 aa)
	STT3B	STT3 oligosaccharyltransferase complex catalytic subunit B. (680 aa)
	ENSSBOP00000002708	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (160 aa)
	DSCC1	DNA replication and sister chromatid cohesion 1. (393 aa)
	COPS5	COP9 signalosome subunit 5. (334 aa)
	PADI4	Peptidyl arginine deiminase 4. (638 aa)
	BAZ1B	Bromodomain adjacent to zinc finger domain 1B. (1339 aa)
	GPLD1	Glycosylphosphatidylinositol specific phospholipase D1. (877 aa)
	SIRT6	Sirtuin 6. (355 aa)
	ENSSBOP00000025764	Ubiquitin carboxyl-terminal hydrolase. (178 aa)
	VIPAS39	VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog. (519 aa)
	ESCO1	Establishment of sister chromatid cohesion N-acetyltransferase 1. (840 aa)
	UBE2M	Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
	AGBL5	ATP/GTP binding protein like 5. (887 aa)
	AGTPBP1	ATP/GTP binding protein 1. (1242 aa)
	ENSSBOP00000020466	Uncharacterized protein. (378 aa)
	FN3K	Fructosamine 3 kinase; Belongs to the fructosamine kinase family. (264 aa)

Your Current Organism:

Saimiri boliviensis

NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG16L1	ATG5	ENSSBOP00000014916	ENSSBOP00000030956	Autophagy related 16 like 1.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG16L1	ATG7	ENSSBOP00000014916	ENSSBOP00000015203	Autophagy related 16 like 1.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.883
ATG16L1	ENSSBOP00000014796	ENSSBOP00000014916	ENSSBOP00000014796	Autophagy related 16 like 1.	Uncharacterized protein.	0.942
ATG16L1	WIPI2	ENSSBOP00000014916	ENSSBOP00000004637	Autophagy related 16 like 1.	Uncharacterized protein.	0.994
ATG5	ATG16L1	ENSSBOP00000030956	ENSSBOP00000014916	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy related 16 like 1.	0.999
ATG5	ATG7	ENSSBOP00000030956	ENSSBOP00000015203	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.993
ATG5	ENSSBOP00000014796	ENSSBOP00000030956	ENSSBOP00000014796	Autophagy protein 5; Involved in autophagic vesicle formation.	Uncharacterized protein.	0.904
ATG5	WIPI2	ENSSBOP00000030956	ENSSBOP00000004637	Autophagy protein 5; Involved in autophagic vesicle formation.	Uncharacterized protein.	0.904
ATG7	ATG16L1	ENSSBOP00000015203	ENSSBOP00000014916	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Autophagy related 16 like 1.	0.883
ATG7	ATG5	ENSSBOP00000015203	ENSSBOP00000030956	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Autophagy protein 5; Involved in autophagic vesicle formation.	0.993
ATG7	ENSSBOP00000002708	ENSSBOP00000015203	ENSSBOP00000002708	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.635
ATG7	ENSSBOP00000009748	ENSSBOP00000015203	ENSSBOP00000009748	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.635
ATG7	ENSSBOP00000014796	ENSSBOP00000015203	ENSSBOP00000014796	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Uncharacterized protein.	0.748
ATG7	ENSSBOP00000018470	ENSSBOP00000015203	ENSSBOP00000018470	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.635
ATG7	ENSSBOP00000032697	ENSSBOP00000015203	ENSSBOP00000032697	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.635
ATG7	RBX1	ENSSBOP00000015203	ENSSBOP00000013291	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ring-box 1.	0.444
ATG7	RNF7	ENSSBOP00000015203	ENSSBOP00000007318	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ring finger protein 7.	0.452
ATG7	SENP8	ENSSBOP00000015203	ENSSBOP00000005375	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	SUMO peptidase family member, NEDD8 specific.	0.458
ATG7	UBE2F	ENSSBOP00000015203	ENSSBOP00000007862	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.635
ATG7	UBE2M	ENSSBOP00000015203	ENSSBOP00000024032	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family.	0.694