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| | ABCA2 | ATP binding cassette subfamily A member 2. (2353 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) |
| | GIP | Gastric inhibitory polypeptide. (124 aa) |
| | ACSL3 | Acyl-CoA synthetase long chain family member 3. (720 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | CGA | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. (120 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (385 aa) |
| | FABP5 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | STAR | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (486 aa) |
| | CEACAM1 | Uncharacterized protein. (523 aa) |
| | LPCAT1 | Lysophosphatidylcholine acyltransferase 1. (521 aa) |
| | ABCG1 | ATP binding cassette subfamily G member 1. (679 aa) |
| | ENSSBOP00000009224 | Uncharacterized protein. (81 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1366 aa) |
| | ORMDL3 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | ENSSBOP00000011012 | CCHC-type domain-containing protein. (587 aa) |
| | MALRD1 | MAM and LDL receptor class A domain containing 1. (2103 aa) |
| | POR | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (680 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa) |
| | HSD17B13 | Hydroxysteroid 17-beta dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (303 aa) |
| | ERLIN2 | ER lipid raft associated 2. (339 aa) |
| | ENSSBOP00000013296 | Protein kinase domain-containing protein. (283 aa) |
| | ENSSBOP00000013304 | ABC transporter domain-containing protein. (162 aa) |
| | IGFBP7 | Insulin like growth factor binding protein 7. (160 aa) |
| | ENSSBOP00000014362 | Protein kinase domain-containing protein. (281 aa) |
| | ENSSBOP00000014709 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (152 aa) |
| | C3 | Complement C3. (1628 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (677 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (801 aa) |
| | CD74 | CD74 molecule. (311 aa) |
| | ENSSBOP00000016113 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (148 aa) |
| | DDX20 | DEAD-box helicase 20. (824 aa) |
| | FABP3 | Fatty acid binding protein 3; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa) |
| | ENSSBOP00000016470 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (358 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (745 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (151 aa) |
| | SAMD8 | Sterile alpha motif domain containing 8. (500 aa) |
| | ENPP7 | Ectonucleotide pyrophosphatase/phosphodiesterase 7. (450 aa) |
| | SERPINA12 | Serpin family A member 12; Belongs to the serpin family. (414 aa) |
| | IDH1 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (326 aa) |
| | MBTPS1 | Membrane bound transcription factor peptidase, site 1. (1053 aa) |
| | NR1H2 | Nuclear receptor subfamily 1 group H member 2. (498 aa) |
| | DHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa) |
| | SNAI2 | Snail family transcriptional repressor 2. (268 aa) |
| | SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa) |
| | ENSSBOP00000038765 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (282 aa) |
| | DAB2 | DAB adaptor protein 2. (767 aa) |
| | CDK4 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa) |
| | FSHB | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. (129 aa) |
| | SF1 | CCHC-type domain-containing protein. (528 aa) |
| | SNAI1 | Snail family transcriptional repressor 1. (265 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | DGAT2 | Diacylglycerol O-acyltransferase 2. (388 aa) |
| | APOA5 | Apolipoprotein A5. (366 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | APOC2 | Proapolipoprotein C-II; Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. Belongs to the apolipoprotein C2 family. (72 aa) |
| | DHCR7 | 7-dehydrocholesterol reductase. (475 aa) |
| | PRMT3 | Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (531 aa) |
| | LPGAT1 | Lysophosphatidylglycerol acyltransferase 1. (370 aa) |
| | NR0B1 | Nuclear receptor subfamily 0 group B member 1. (470 aa) |
| | ADGRF5 | Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1345 aa) |
| | THRSP | Thyroid hormone responsive. (146 aa) |
| | MFSD2A | Major facilitator superfamily domain containing 2A. (530 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | SIRT1 | Sirtuin 1. (453 aa) |
| | APOE | Apolipoprotein E. (261 aa) |
| | PLA2G6 | Phospholipase A2 group VI. (798 aa) |
| | RAB38 | RAB38, member RAS oncogene family. (211 aa) |
| | PLA2G3 | Phospholipase A2 group III. (509 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa) |
| | ABCD2 | ATP binding cassette subfamily D member 2. (740 aa) |
| | ERLIN1 | ER lipid raft associated 1. (348 aa) |
| | SREBF2 | Sterol regulatory element binding transcription factor 2. (1119 aa) |
| | ORMDL1 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | ADM | Adrenomedullin. (187 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | SEC14L4 | SEC14 like lipid binding 4. (406 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | REST | RE1 silencing transcription factor. (1110 aa) |
| | ASXL3 | ASXL transcriptional regulator 3. (2232 aa) |
| | ORMDL2 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | SPHK2 | Sphingosine kinase 2. (656 aa) |
| | ENSSBOP00000030062 | Uncharacterized protein. (54 aa) |
| | GFI1 | Growth factor independent 1 transcriptional repressor. (422 aa) |
| | BMP6 | Bone morphogenetic protein 6. (508 aa) |
| | ARMC5 | Armadillo repeat containing 5. (1030 aa) |
| | SORBS1 | Sorbin and SH3 domain containing 1. (1544 aa) |
| | ZBTB20 | Zinc finger and BTB domain containing 20. (741 aa) |
| | ASAH1 | N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (432 aa) |
| | SLC27A1 | Solute carrier family 27 member 1. (646 aa) |
| | LPIN1 | Lipin 1. (975 aa) |
| | HTR2A | 5-hydroxytryptamine receptor 2A. (471 aa) |
| | XBP1 | BZIP domain-containing protein. (375 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (481 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | FAM3A | Family with sequence similarity 3 member A. (230 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa) |
| | DKKL1 | Dickkopf like acrosomal protein 1. (251 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | CREBL2 | cAMP responsive element binding protein like 2. (120 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1230 aa) |
| | PDK4 | Protein-serine/threonine kinase. (411 aa) |
| | PRKCD | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (720 aa) |
| | GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (877 aa) |
| | SCP2 | Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (463 aa) |
| | DGKQ | Diacylglycerol kinase. (1006 aa) |
| | AVPR1A | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (418 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (706 aa) |
| | NR3C1 | Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...] (777 aa) |
| | LDLR | Low density lipoprotein receptor. (569 aa) |
| | ABCG4 | ATP binding cassette subfamily G member 4. (646 aa) |
| | SCAP | SREBF chaperone. (1278 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (451 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1673 aa) |
| | CLCN2 | Chloride channel protein. (974 aa) |
| | ABCA3 | ATP binding cassette subfamily A member 3. (1703 aa) |
| | H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (802 aa) |
| | SEC14L2 | Uncharacterized protein. (403 aa) |
| | NR5A1 | Nuclear receptor subfamily 5 group A member 1. (461 aa) |
| | MLXIPL | MLX interacting protein like. (853 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (341 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1335 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (301 aa) |
| | PLIN5 | Perilipin; Belongs to the perilipin family. (378 aa) |
| | CES4A | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (463 aa) |
| | BMP5 | Bone morphogenetic protein 5. (454 aa) |
| | CTDNEP1 | CTD nuclear envelope phosphatase 1. (244 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (468 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (249 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (553 aa) |
| | LPCAT3 | Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa) |
| | CNEP1R1 | CTD nuclear envelope phosphatase 1 regulatory subunit 1. (142 aa) |
| | CCDC3 | Coiled-coil domain containing 3. (145 aa) |
| | SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (551 aa) |
| | SEC14L5 | SEC14 like lipid binding 5. (696 aa) |
| | BMP2 | Bone morphogenetic protein 2. (396 aa) |
| | SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa) |
| | SPHK1 | Sphingosine kinase 1. (488 aa) |
| | ABHD6 | Abhydrolase domain containing 6. (337 aa) |
| | APOB | Apolipoprotein B. (4562 aa) |
| | STARD4 | StAR related lipid transfer domain containing 4. (206 aa) |
| | MID1IP1 | MID1 interacting protein 1. (183 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (615 aa) |
| | GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | PIBF1 | Progesterone immunomodulatory binding factor 1. (735 aa) |
| | CCN1 | Cellular communication network factor 1. (381 aa) |
| | CES1 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (394 aa) |
| | AVIL | Advillin. (819 aa) |
| | FITM2 | Fat storage inducing transmembrane protein 2. (262 aa) |
| | LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (731 aa) |
| | SEC14L3 | SEC14 like lipid binding 3. (400 aa) |
| | ENSSBOP00000006325 | Uncharacterized protein. (115 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (486 aa) |
| | SIRT3 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (420 aa) |
