(24 nodes) Positive regulation of oligodendrocyte differentiation network (Saimiri boliviensis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	NKX6-1	NK6 homeobox 1. (366 aa)
	ENSSBOP00000031285	Uncharacterized protein. (154 aa)
	PTPRZ1	Protein tyrosine phosphatase receptor type Z1. (2326 aa)
	ZNF365	Zinc finger protein 365. (407 aa)
	ENSSBOP00000021549	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (421 aa)
	ENSSBOP00000020558	Uncharacterized protein. (130 aa)
	HDAC2	Hist_deacetyl domain-containing protein. (314 aa)
	ENSSBOP00000035139	Uncharacterized protein. (126 aa)
	DAG1	Dystroglycan 1. (895 aa)
	ACY3	Aminoacylase 3. (319 aa)
	IL34	Interleukin 34. (242 aa)
	ENSSBOP00000005807	HH_signal domain-containing protein. (115 aa)
	TP73	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (635 aa)
	TNFRSF1B	TNF receptor superfamily member 1B. (462 aa)
	TENM4	Teneurin transmembrane protein 4. (2864 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
	ASPA	Aspartoacylase. (281 aa)
	OLIG2	Oligodendrocyte transcription factor 2. (202 aa)
	NKX2-2	NK2 homeobox 2. (402 aa)
	ENSSBOP00000039148	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (392 aa)
	RHEB	Uncharacterized protein. (492 aa)
	ENSSBOP00000037087	Hist_deacetyl domain-containing protein. (226 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
	PTN	Uncharacterized protein. (168 aa)

Your Current Organism:

Saimiri boliviensis

NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSBOP00000005807	NKX2-2	ENSSBOP00000005807	ENSSBOP00000031756	HH_signal domain-containing protein.	NK2 homeobox 2.	0.438
ENSSBOP00000005807	OLIG2	ENSSBOP00000005807	ENSSBOP00000033770	HH_signal domain-containing protein.	Oligodendrocyte transcription factor 2.	0.645
ENSSBOP00000020558	ENSSBOP00000031285	ENSSBOP00000020558	ENSSBOP00000031285	Uncharacterized protein.	Uncharacterized protein.	0.480
ENSSBOP00000020558	PTN	ENSSBOP00000020558	ENSSBOP00000035430	Uncharacterized protein.	Uncharacterized protein.	0.480
ENSSBOP00000020558	PTPRZ1	ENSSBOP00000020558	ENSSBOP00000029901	Uncharacterized protein.	Protein tyrosine phosphatase receptor type Z1.	0.564
ENSSBOP00000021549	ENSSBOP00000037087	ENSSBOP00000021549	ENSSBOP00000037087	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Hist_deacetyl domain-containing protein.	0.842
ENSSBOP00000021549	HDAC2	ENSSBOP00000021549	ENSSBOP00000019047	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Hist_deacetyl domain-containing protein.	0.842
ENSSBOP00000031285	ENSSBOP00000020558	ENSSBOP00000031285	ENSSBOP00000020558	Uncharacterized protein.	Uncharacterized protein.	0.480
ENSSBOP00000031285	ENSSBOP00000035139	ENSSBOP00000031285	ENSSBOP00000035139	Uncharacterized protein.	Uncharacterized protein.	0.480
ENSSBOP00000031285	PTPRZ1	ENSSBOP00000031285	ENSSBOP00000029901	Uncharacterized protein.	Protein tyrosine phosphatase receptor type Z1.	0.814
ENSSBOP00000035139	ENSSBOP00000031285	ENSSBOP00000035139	ENSSBOP00000031285	Uncharacterized protein.	Uncharacterized protein.	0.480
ENSSBOP00000035139	PTN	ENSSBOP00000035139	ENSSBOP00000035430	Uncharacterized protein.	Uncharacterized protein.	0.480
ENSSBOP00000035139	PTPRZ1	ENSSBOP00000035139	ENSSBOP00000029901	Uncharacterized protein.	Protein tyrosine phosphatase receptor type Z1.	0.564
ENSSBOP00000037087	ENSSBOP00000021549	ENSSBOP00000037087	ENSSBOP00000021549	Hist_deacetyl domain-containing protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.842
ENSSBOP00000037087	ENSSBOP00000039148	ENSSBOP00000037087	ENSSBOP00000039148	Hist_deacetyl domain-containing protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.840
ENSSBOP00000037087	HDAC1	ENSSBOP00000037087	ENSSBOP00000018138	Hist_deacetyl domain-containing protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.840
ENSSBOP00000039148	ENSSBOP00000037087	ENSSBOP00000039148	ENSSBOP00000037087	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Hist_deacetyl domain-containing protein.	0.840
ENSSBOP00000039148	HDAC2	ENSSBOP00000039148	ENSSBOP00000019047	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Hist_deacetyl domain-containing protein.	0.841
HDAC1	ENSSBOP00000037087	ENSSBOP00000018138	ENSSBOP00000037087	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Hist_deacetyl domain-containing protein.	0.840
HDAC1	HDAC2	ENSSBOP00000018138	ENSSBOP00000019047	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Hist_deacetyl domain-containing protein.	0.983